Gene: Ctnnbip1

Basic information

Tag Content
Uniprot ID Q4KM58
Entrez ID 503000
Genbank protein ID EDL81168.1; EDL81167.1; AAH98773.1;
Genbank nucleotide ID NM_001173388.1; XM_006239436.3;
Ensembl protein ID ENSRNOP00000052425
Ensembl nucleotide ID ENSRNOG00000016313
Gene name Catenin, beta-interacting protein 1
Gene symbol Ctnnbip1
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTASEEEF LRTYAGVVNS QLSQLPQHSI 60
DQGAEDVVMA FSRSETEDRR Q 81

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCTNNBIP1614630Q5E9N2Bos taurusPredictionMore>>
1:1 orthologCLSTN1479600E2QVY5Canis lupus familiarisPredictionMore>>
1:1 orthologCTNNBIP1102173591A0A452FWJ1Capra hircusPredictionMore>>
1:1 orthologCTNNBIP156998Q9NSA3Homo sapiensPredictionMore>>
1:1 orthologCtnnbip167087Q9JJN6CPOMus musculusPublicationMore>>
1:1 orthologCTNNBIP1749394H2R3P1Pan troglodytesPredictionMore>>
1:1 orthologCTNNBIP1A0A287ADI4Sus scrofaPredictionMore>>
1:1 orthologCtnnbip1503000Q4KM58Rattus norvegicusPredictionMore>>
1:1 orthologctnnbip158117Q9I903Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0030877 beta-catenin destruction complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005634 nucleus
GO:0070016 armadillo repeat domain binding
GO:0008013 beta-catenin binding
GO:0009952 anterior/posterior pattern specification
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0043392 negative regulation of DNA binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0072201 negative regulation of mesenchymal cell proliferation
GO:0032091 negative regulation of protein binding
GO:0031333 negative regulation of protein-containing complex assembly
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter
GO:0030178 negative regulation of Wnt signaling pathway
GO:0045657 positive regulation of monocyte differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0002528 regulation of vascular permeability involved in acute inflammatory response
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR042999 CTNNBIP1
IPR009428 ICAT_dom
IPR036911 ICAT_sf

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF06384 ICAT