CleftGeneDB-Search

Gene: CTNNBIP1

Basic information

Tag	Content
Uniprot ID	Q5E9N2
Entrez ID	614630
Genbank protein ID	AAX08905.1
Genbank nucleotide ID	XM_010813275.2; NM_001037142.1; XM_005216982.2;
Ensembl protein ID	ENSBTAP00000007790; ENSBTAP00000068342;
Ensembl nucleotide ID	ENSBTAG00000005933
Gene name	Beta-catenin-interacting protein 1
Gene symbol	CTNNBIP1
Organism	Bos taurus
NCBI taxa ID	9913
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description	Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.
Sequence	MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTANEEEF LRTYAGVVNS QLSQLPQHSI 60 DQGAEDVVMA FSRSETEDRR Q 81

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

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Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Species	Evidence	Details
1:1 ortholog	Ctnnbip1	67087	Q9JJN6	CPO	Mus musculus	Publication	More>>
1:1 ortholog	CLSTN1	479600	E2QVY5		Canis lupus familiaris	Prediction	More>>
1:1 ortholog	CTNNBIP1	614630	Q5E9N2		Bos taurus	Prediction	More>>
1:1 ortholog	CTNNBIP1	102173591	A0A452FWJ1		Capra hircus	Prediction	More>>
1:1 ortholog	CTNNBIP1	56998	Q9NSA3		Homo sapiens	Prediction	More>>
1:1 ortholog	CTNNBIP1	749394	H2R3P1		Pan troglodytes	Prediction	More>>
1:1 ortholog	CTNNBIP1		A0A287ADI4		Sus scrofa	Prediction	More>>
1:1 ortholog	Ctnnbip1	503000	Q4KM58		Rattus norvegicus	Prediction	More>>
1:1 ortholog	ctnnbip1	58117	Q9I903		Danio rerio	Prediction	More>>

Showing 1 to 9 of 9 entries

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Gene ontology

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GO ID	GO Term
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0002528	regulation of vascular permeability involved in acute inflammatory response
GO:0005634	nucleus
GO:0005829	cytosol
GO:0008013	beta-catenin binding
GO:0009952	anterior/posterior pattern specification
GO:0016055	Wnt signaling pathway
GO:0030178	negative regulation of Wnt signaling pathway
GO:0030877	beta-catenin destruction complex
GO:0031333	negative regulation of protein-containing complex assembly
GO:0032091	negative regulation of protein binding
GO:0043392	negative regulation of DNA binding
GO:0043433	negative regulation of DNA-binding transcription factor activity
GO:0045657	positive regulation of monocyte differentiation
GO:0045669	positive regulation of osteoblast differentiation
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter
GO:0070016	armadillo repeat domain binding
GO:0072201	negative regulation of mesenchymal cell proliferation