Gene: gsc

Basic information

Tag Content
Uniprot ID Q7ZZR4
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000076522; ENSDARP00000152351;
Ensembl nucleotide ID ENSDARG00000059073; ENSDARG00000115937;
Gene name Homeobox protein goosecoid
Gene symbol gsc
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPAGMFSIDS ILAGRPSCKD SVLLHRNAPV VFSNLTESLY TAAGDFNGLY SHTGPPAPNL 60
QSVNGRIGYN NYYYGQLHVQ GPTGPACCGA IPTLGSQQCP CIHTGYDSAG SVLISPVPHQ 120
MMSYMNVGTL SRTELQLLNQ LHCRRKRRHR TIFTDEQLEA LENLFQETKY PDVGTREQLA 180
RKVHLREEKV EVWFKNRRAK WRRQKRSSSE ESENSQKWNK STKTTSEKIE EGKSDVDSDS 240

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologGSC514862E1BB15Bos taurusPredictionMore>>
1:1 orthologGSC102185957A0A452FMK4Capra hircusPredictionMore>>
1:1 orthologGSC145258P56915Homo sapiensPredictionMore>>
1:1 orthologGsc14836Q02591CPOE12.5, E13.75, E13.5, E14.5, E15.5Mus musculusPublicationMore>>
1:1 orthologGSC467546A2T733Pan troglodytesPredictionMore>>
1:1 orthologGSC397342F1SCC4Sus scrofaPredictionMore>>
1:1 orthologGsc317715G3V7E7Rattus norvegicusPredictionMore>>
1:1 orthologgscQ7ZZR4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain