Gene: pax9

Basic information

Tag Content
Uniprot ID Q98865
Entrez ID 30558
Genbank protein ID AAC60034.1
Genbank nucleotide ID NM_131298.1
Ensembl protein ID ENSDARP00000070415
Ensembl nucleotide ID ENSDARG00000053829
Gene name Paired box protein Pax-9
Gene symbol pax9
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MEPAFGEVNQ LGGVFVNGRP LPNAIRLRIV ELAQLGIRPC DISRQLRVSH GCVSKILARY 60
NETGSILPGA IGGSKPRVTT PNVVKHIRTY KQRDPGIFAW EIRDRLLADG VCDKFNLPSV 120
SSISRILRNK IGNLSQQNQY ESSKQASHPQ PQPTIPYNHL YSYPTPIAAA GTKVPTPPGM 180
PTLPGHMAMH RIWPSSHSVT DILGIRSITE QQISDNPSFP SAKLEEWRAI NRSNFSPANS 240
PLVNGVDKPH LEPEAKYNQT PNGLPTVNSY VTAPSIHHYH PPTQVSPYMG YSGTTSAYVT 300
GPTWQPPSGS ALSPHSCDIS SPLAFKSMSA TRDSVHSLVA SAL 343

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPAX9540196F1MFP5Bos taurusPredictionMore>>
1:1 orthologPAX9102171104A0A452EZP5Capra hircusPredictionMore>>
1:1 orthologPAX95083P55771CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologPax918511P47242CPO,CLPE14.5Mus musculusPublicationMore>>
1:1 orthologPAX9737458Q2VL62Pan troglodytesPredictionMore>>
1:1 orthologPAX9100156821A0A480DYY0Sus scrofaPredictionMore>>
1:1 orthologPax9R9PXT8Rattus norvegicusPredictionMore>>
1:1 orthologpax930558Q98865Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding
GO:0048856 anatomical structure development
GO:0009887 animal organ morphogenesis
GO:0006357 regulation of transcription by RNA polymerase II
GO:0060021 roof of mouth development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-0539 Nucleus
KW-0563 Paired box
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR043182 PAIRED_DNA-bd_dom
IPR001523 Paired_dom
IPR033204 PAX9
IPR043565 PAX_fam
IPR036388 WH-like_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS00034 PAIRED_1
PS51057 PAIRED_2

Pfam

Pfam ID Pfam Term
PF00292 PAX