Gene: Rpl38

Basic information

Tag Content
Uniprot ID Q9JJI8
Entrez ID 67671
Genbank protein ID BAB22266.1; BAB03500.1; BAB28208.1; AAH55346.1; BAB26814.1; BAB27000.1;
Genbank nucleotide ID NM_001048057.1; NM_001048058.1; XM_006534009.2; XM_017314720.1; NM_023372.2;
Ensembl protein ID ENSMUSP00000102213; ENSMUSP00000080741; ENSMUSP00000102211; ENSMUSP00000102209;
Ensembl nucleotide ID ENSMUSG00000057322
Gene name 60S ribosomal protein L38
Gene symbol Rpl38
Organism Mus musculus
NCBI taxa ID 10090
Cleft type CPO,CLP,CLO
Developmental stage
Data sources Manually collected
Reference 10889952; 21529712;
Functional description
Sequence
MPRKIEEIKD FLLTARRKDA KSVKIKKNKD NVKFKVRCSR YLYTLVITDK EKAEKLKQSL 60
PPGLAVKDLK

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRPL38A0A452G9G0Capra hircusPredictionMore>>
1:1 orthologRPL38100630893F7AB94Equus caballusPredictionMore>>
1:1 orthologRPL386169P63173Homo sapiensPredictionMore>>
1:1 orthologRpl3867671Q9JJI8CPO,CLP,CLOMus musculusPublicationMore>>
1:1 orthologRPL38745405A0A2J8KC40Pan troglodytesPredictionMore>>
1:1 ortholog100516393F2Z568Sus scrofaPredictionMore>>
1:1 orthologrpl38436759Q6DGL9Danio rerioPredictionMore>>

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID GO Term Evidence
GO:0003735 structural constituent of ribosomeIBA

GO:Biological Process

GO ID GO Term Evidence
GO:0001501 skeletal system developmentIMP
GO:0001501 skeletal system developmentTAS
GO:0001503 ossificationIMP
GO:0002181 cytoplasmic translationISO
GO:0006417 regulation of translationIMP
GO:0007605 sensory perception of soundIMP
GO:0022618 ribonucleoprotein complex assemblyIBA
GO:0034463 90S preribosome assemblyIDA
GO:0042474 middle ear morphogenesisIMP
GO:0048318 axial mesoderm developmentIMP

GO:Cellular Component

GO ID GO Term Evidence
GO:0014069 postsynaptic densityISO
GO:0022625 cytosolic large ribosomal subunitISO
GO:0022625 cytosolic large ribosomal subunitIBA
GO:0033291 eukaryotic 80S initiation complexIDA
GO:0042788 polysomal ribosomeISO
GO:0045202 synapseEXP
GO:0045202 synapseIDA

Reactome Pathway

Reactome ID Reactome Term Evidence
R-MMU-156827 L13a-mediated translational silencing of Ceruloplasmin expressionIEA
R-MMU-1799339 SRP-dependent cotranslational protein targeting to membraneIEA
R-MMU-392499 Metabolism of proteinsIEA
R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosolIEA
R-MMU-72312 rRNA processingIEA
R-MMU-72613 Eukaryotic Translation InitiationIEA
R-MMU-72689 Formation of a pool of free 40S subunitsIEA
R-MMU-72706 GTP hydrolysis and joining of the 60S ribosomal subunitIEA
R-MMU-72737 Cap-dependent Translation InitiationIEA
R-MMU-72766 TranslationIEA
R-MMU-8868773 rRNA processing in the nucleus and cytosolIEA
R-MMU-8953854 Metabolism of RNAIEA
R-MMU-927802 Nonsense-Mediated Decay (NMD)IEA
R-MMU-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)IEA
R-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)IEA

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0007 Acetylation
KW-1017 Isopeptide bond
KW-1185 Reference proteome
KW-0687 Ribonucleoprotein
KW-0689 Ribosomal protein
KW-0832 Ubl conjugation

Interpro

InterPro ID InterPro Term
IPR002675 Ribosomal_L38e
IPR038464 Ribosomal_L38e_sf

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF01781 Ribosomal_L38e

Protein-protein interaction