| Tag | Content |
|---|---|
| Uniprot ID | Q9YH60 |
| Entrez ID | 30654 |
| Genbank protein ID | AAI62371.1; CAA11420.1; |
| Genbank nucleotide ID | NM_131381.1 |
| Ensembl protein ID | ENSDARP00000027785 |
| Ensembl nucleotide ID | ENSDARG00000017803 |
| Gene name | Glycogen synthase kinase-3 beta |
| Gene symbol | gsk3ba |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSGRPRTTSF AESCKPVPQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR PQEVSYTDTK 60 VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI MRKLDHCNIV RLRYFFYSSG 120 DKKDEVYLNL VLDYVPETVY RVARHYSRAK QTLPMVYVKL YMYQLFRSLA YIHSFGICHR 180 DIKPQNLLLD PDTAVLKLCD FGSAKQLVRG EPNVSYICSR YYRAPELIFG ATDYTSSIDV 240 WSAGCVLAEL LLGQPIFPGD SGVDQLVEII KVLGTPTREQ IREMNPNYTE FKFPQIKAHP 300 WTKVFRPRTP PEAIALCSRL LEYTPTARLT PLEACAHSFF DELREPNVKL PNGREKPSLF 360 NFTTQELSSN PTLASILIPA HARNQAGAST PTNPSATSDA NSGDRSQTTT AASASASNTS 420 T 421 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GSK3B | 478575 | E2RB53 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | GSK3B1 | 102176363 | A0A097P8R4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GSK3B | 2932 | P49841 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gsk3b | 56637 | Q9WV60 | CPO | E12.5, E13.5, E14.5, P6 | Mus musculus | Publication | More>> |
| 1:1 ortholog | GSK3B | 100616510 | K7CFX8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GSK3B | I6ZJZ7 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GSK3B | 100348842 | A0A5F9CM08 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gsk3b | 84027 | A0A0G2KB98 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gsk3ba | 30654 | Q9YH60 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030424 | axon |
| GO:0030877 | beta-catenin destruction complex |
| GO:0005737 | cytoplasm |
| GO:0005829 | cytosol |
| GO:0098978 | glutamatergic synapse |
| GO:0005634 | nucleus |
| GO:0005886 | plasma membrane |
| GO:0005524 | ATP binding |
| GO:0008013 | beta-catenin binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0050321 | tau-protein kinase activity |
| GO:0001525 | angiogenesis |
| GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand |
| GO:0003146 | heart jogging |
| GO:0001947 | heart looping |
| GO:0008286 | insulin receptor signaling pathway |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway |
| GO:0070507 | regulation of microtubule cytoskeleton organization |
| GO:0010975 | regulation of neuron projection development |
| GO:0048511 | rhythmic process |
| GO:0007165 | signal transduction |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |