Gene: raraa

Basic information

Tag Content
Uniprot ID T2DKU4
Entrez ID 30680
Genbank protein ID AGV53011.1
Genbank nucleotide ID XM_005156052.3
Ensembl protein ID ENSDARP00000139532
Ensembl nucleotide ID ENSDARG00000056783
Gene name Retinoic acid receptor alpha a 201
Gene symbol raraa
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSGKGNPSPH LNGFPMAHFS YFFPHMLGGL SPPSLPTLPL SGYSTPSPAT IETQSTSSEE 60
IVPSPPSPPP PPRIYKPCFV CQDKSSGYHY GVSACEGCKG FFRRSIQKNM VYTCHREKNC 120
IINKVTRNRC QYCRLQKCLE VGMSKESVRN DRNKKKKEEK KPECTENYTL SPDTEQMIDR 180
VRKAHQETFP SLCQLGKYTT SNSSERRVAL DVDLWDKFSE LSTKCIIKTV EFAKQLPGFT 240
TLTIADQITL LKAACLDILI LRICTRYTPE QDTMTFSDGL TLNRTQMHNA GFGPLTDLVF 300
AFANQLLPLE MDDAETGLLS AICLLCGDRQ DLEQADKVDV LQEPLLEALK IYVRNRRPHK 360
PHMFPKMLMK ITDLRSISAK GAERVITLKM EIPGSMPPLI QEMLENSEGL ESSSGAQGSR 420
ASATTPGSCS PSLSPNSAQS SPPTQSP 447

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRARA534280F1MWQ3Bos taurusPredictionMore>>
1:1 orthologRARA102188350A0A452EMU9Capra hircusPredictionMore>>
1:1 orthologRARA5914P10276CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologRara19401P11416CPOE14.5Mus musculusPublicationMore>>
1:1 orthologRARA454647A0A2J8KGL7Pan troglodytesPredictionMore>>
1:1 orthologRARA396709A0A480PNE7Sus scrofaPredictionMore>>
1:1 orthologRARAG1TI43Oryctolagus cuniculusPredictionMore>>
1:1 orthologRara24705A0A0G2JW78Rattus norvegicusPredictionMore>>
1:1 ortholograraa30680T2DKU4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0004879 nuclear receptor activity
GO:0043565 sequence-specific DNA binding
GO:0008270 zinc ion binding
GO:0048384 retinoic acid receptor signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0479 Metal-binding
KW-0539 Nucleus
KW-0675 Receptor
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR035500 NHR-like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR003078 Retinoic_acid_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA

PROSITE

PROSITE ID PROSITE Term
PS51843 NR_LBD
PS00031 NUCLEAR_REC_DBD_1
PS51030 NUCLEAR_REC_DBD_2

Pfam

Pfam ID Pfam Term
PF00104 Hormone_recep
PF00105 zf-C4