Gene Page: TWIST2

Summary
GeneID  117581
Symbol  TWIST2
Synonyms  DERMO1|MGC117334|bHLHa39
Description  twist homolog 2 (Drosophila)
See related  HGNC:20670|MIM:607556|HPRD:09616|
Locus tag  -
Gene type  protein-coding
Map location  2q37.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.684 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0005515protein bindingIPI18598946 
GO:0016564transcription repressor activityISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
GO:0045892negative regulation of transcription, DNA-dependentISS-
GO:0045668negative regulation of osteoblast differentiationIDA11062344 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA11062344 
GO:0005737cytoplasmIDA11062344 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MEF2C-myocyte enhancer factor 2C-HPRD,BioGRID11809751 
SREBF1SREBP-1c | SREBP1 | bHLHd1sterol regulatory element binding transcription factor 1-HPRD,BioGRID14654692 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP 2921All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN 3324All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
WONG_ENDMETRIUM_CANCER_DN 8253All SZGR genes in this pathway
INGRAM_SHH_TARGETS_UP 12779All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN 411249All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
BURTON_ADIPOGENESIS_8 8657All SZGR genes in this pathway
CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN 3623All SZGR genes in this pathway
NADELLA_PRKAR1A_TARGETS_DN 88All SZGR genes in this pathway
SCHRAETS_MLL_TARGETS_DN 3324All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
CHANDRAN_METASTASIS_DN 306191All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_MIDDLE 9856All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway


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