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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CLK2

Summary

GeneID

1196

Symbol

CLK2

Synonyms

MGC61500|hCLK2

Description

CDC-like kinase 2

Locus tag

Gene type

protein-coding

Map location

1q21

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00814

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0005524

ATP binding

IEA

GO:0004674

protein serine/threonine kinase activity

TAS

7990150

GO:0004713

protein tyrosine kinase activity

IEA

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006468

protein amino acid phosphorylation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CLK3	FLJ22858 \| PHCLK3 \| PHCLK3/152	CDC-like kinase 3	Two-hybrid	BioGRID	16189514
UBL5	FLJ46917 \| HUB1 \| MGC131795	ubiquitin-like 5	Reconstituted Complex	BioGRID	12705895
YWHAG	14-3-3GAMMA	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	-	HPRD	15324660

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
PARENT_MTOR_SIGNALING_UP	567	375	All SZGR genes in this pathway
PATIL_LIVER_CANCER	747	453	All SZGR genes in this pathway
AMUNDSON_RESPONSE_TO_ARSENITE	217	143	All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK	1442	892	All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON	38	18	All SZGR genes in this pathway
NATSUME_RESPONSE_TO_INTERFERON_BETA_UP	71	49	All SZGR genes in this pathway
HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR	37	22	All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1	528	324	All SZGR genes in this pathway
GRADE_COLON_CANCER_UP	871	505	All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP	374	247	All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S2	115	74	All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN	225	124	All SZGR genes in this pathway
KAMMINGA_SENESCENCE	41	26	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN	254	158	All SZGR genes in this pathway
LU_EZH2_TARGETS_DN	414	237	All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP	504	321	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-199	56	62	m8	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	56	62	m8	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-27	123	129	1A	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	123	129	1A	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-29	60	66	m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.