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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: DTNB

Summary

GeneID

1838

Symbol

DTNB

Synonyms

MGC17163|MGC57126

Description

dystrobrevin, beta

Locus tag

Gene type

protein-coding

Map location

2p24

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.2064

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

JPH4

0.91

0.92

DMWD

0.89

FBXO41

0.88

0.91

REXO1

0.87

0.89

C11orf81

0.87

0.88

JPH3

0.87

0.90

SEMA6B

0.86

0.88

MGAT5B

0.86

0.88

AGAP2

0.86

0.88

C19orf26

0.86

0.87

Top 10 negatively co-expressed genes

AF347015.21

-0.56

-0.47

AL139819.3

-0.55

GNG11

-0.54

-0.53

AP002478.3

-0.53

-0.52

C1orf54

-0.51

-0.52

MT-CO2

-0.51

-0.43

AF347015.31

-0.50

-0.43

NOSTRIN

-0.50

-0.45

AF347015.18

-0.48

-0.37

AF347015.8

-0.48

-0.40

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005509

calcium ion binding

IEA

GO:0005515

protein binding

TAS

9395493

GO:0008270

zinc ion binding

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0045202

synapse

IEA

neuron, Synap, Neurotransmitter, Glial (GO term level: 2)

GO:0005737

cytoplasm

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
BEGAIN	KIAA1446	brain-enriched guanylate kinase-associated homolog (rat)	Two-hybrid	BioGRID	16189514
C1orf182	MGC26877 \| RP11-443G18.5 \| SSTK-IP	chromosome 1 open reading frame 182	Two-hybrid	BioGRID	16189514
CCDC85B	DIPA	coiled-coil domain containing 85B	Two-hybrid	BioGRID	16189514
DMD	BMD \| CMD3B \| DXS142 \| DXS164 \| DXS206 \| DXS230 \| DXS239 \| DXS268 \| DXS269 \| DXS270 \| DXS272	dystrophin	Affinity Capture-Western	BioGRID	10545507
DTNBP1	DBND \| DKFZp564K192 \| FLJ30031 \| HPS7 \| MGC20210 \| My031 \| SDY	dystrobrevin binding protein 1	-	HPRD	11316798
HMG20A	FLJ10739 \| HMGX1	high-mobility group 20A	Two-hybrid	BioGRID	16189514
KIF5A	D12S1889 \| MY050 \| NKHC \| SPG10	kinesin family member 5A	-	HPRD,BioGRID	14600269
KIF5B	KINH \| KNS \| KNS1 \| UKHC	kinesin family member 5B	Reconstituted Complex	BioGRID	14600269
NUP62	DKFZp547L134 \| FLJ20822 \| FLJ43869 \| IBSN \| MGC841 \| SNDI \| p62	nucleoporin 62kDa	Two-hybrid	BioGRID	16189514
PPFIBP2	Cclp1 \| DKFZp781K06126 \| MGC42541	PTPRF interacting protein, binding protein 2 (liprin beta 2)	Two-hybrid	BioGRID	16189514
PRTFDC1	FLJ11888 \| HHGP	phosphoribosyl transferase domain containing 1	Two-hybrid	BioGRID	16189514
SNTA1	SNT1 \| TACIP1 \| dJ1187J4.5	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	Affinity Capture-Western	BioGRID	10545507
SNTG1	G1SYN \| SYN4	syntrophin, gamma 1	-	HPRD	10747910
SNTG2	G2SYN \| MGC133174 \| SYN5	syntrophin, gamma 2	-	HPRD	10747910
TRAF2	MGC:45012 \| TRAP \| TRAP3	TNF receptor-associated factor 2	Two-hybrid	BioGRID	16189514
UTRN	DMDL \| DRP \| DRP1 \| FLJ23678	utrophin	-	HPRD	10545507

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
VECCHI_GASTRIC_CANCER_EARLY_DN	367	220	All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP	530	342	All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP	390	236	All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_D	37	14	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_16HR_UP	225	139	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_24HR_UP	148	96	All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP	181	112	All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN	564	326	All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP	476	285	All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING	510	309	All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12	317	177	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-143	284	290	m8	hsa-miR-143^brain	UGAGAUGAAGCACUGUAGCUCA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.