Gene Page: EMX2

Summary
GeneID  2018
Symbol  EMX2
Synonyms  -
Description  empty spiracles homeobox 2
See related  HGNC:3341|MIM:600035|Ensembl:ENSG00000170370|HPRD:02495|
Locus tag  -
Gene type  protein-coding
Map location  10q26.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CREBBP0.980.98
TRRAP0.980.98
INSR0.970.98
C11orf300.970.96
ARID1A0.970.97
EP4000.970.97
ZZEF10.970.97
POGZ0.960.97
SEC16A0.960.97
GATAD2B0.960.95
Top 10 negatively co-expressed genes
AF347015.31-0.70-0.84
MT-CO2-0.69-0.84
FXYD1-0.68-0.82
IFI27-0.68-0.81
C5orf53-0.68-0.73
S100B-0.68-0.79
HIGD1B-0.67-0.84
AF347015.27-0.67-0.80
SERPINB6-0.66-0.70
AF347015.33-0.66-0.77
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0005515protein bindingIPI15247416 
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030182neuron differentiationIEAneuron (GO term level: 8)-
GO:0030900forebrain developmentIEABrain (GO term level: 8)-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0009952anterior/posterior pattern formationIEA-
GO:0007275multicellular organismal developmentNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusNAS-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
LEE_NEURAL_CREST_STEM_CELL_DN 11879All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
LEIN_ASTROCYTE_MARKERS 4235All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN 2416All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
WINNEPENNINCKX_MELANOMA_METASTASIS_DN 4626All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN 7447All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-130/301498504m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-148/152112311291Ahsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
miR-19497503m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-22253259m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-33947541A,m8hsa-miR-339UCCCUGUCCUCCAGGAGCUCA
miR-3708228281Ahsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
miR-495122812341Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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