Gene Page: EN2

Summary
GeneID  2020
Symbol  EN2
Synonyms  AUTS1|AUTS10
Description  engrailed homeobox 2
See related  HGNC:3343|MIM:131310|Ensembl:ENSG00000164778|HPRD:08836|
Locus tag  -
Gene type  protein-coding
Map location  7q36
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CNOT60.960.93
ATAD2B0.950.88
PBRM10.950.93
ARID20.950.93
MED10.940.93
IGF2BP30.940.77
MBTD10.940.92
CASP20.940.92
MYST30.940.92
ZNF4450.940.92
Top 10 negatively co-expressed genes
C5orf53-0.70-0.76
PTH1R-0.69-0.76
LHPP-0.69-0.62
HLA-F-0.68-0.73
AIFM3-0.68-0.73
ALDOC-0.68-0.68
FBXO2-0.68-0.65
TNFSF12-0.67-0.69
SLC16A11-0.67-0.69
AF347015.31-0.66-0.88
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0048666neuron developmentIEAneuron (GO term level: 9)-
GO:0030902hindbrain developmentIEABrain (GO term level: 8)-
GO:0030901midbrain developmentIEABrain (GO term level: 8)-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0007275multicellular organismal developmentTAS1672471 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FOXA2HNF3B | MGC19807 | TCF3Bforkhead box A2Reconstituted ComplexBioGRID12642491 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_UP 292168All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_DN 185111All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP 240152All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
LEIN_CEREBELLUM_MARKERS 8547All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3 9772All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_WITH_H3K27ME3 19693All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 196124All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_3_DN 3921All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-103/1073843901Ahsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-124.1175417611A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/506175417601Ahsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-1284004061Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-13886921Ahsa-miR-138brainAGCUGGUGUUGUGAAUC
miR-18120242030m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-1936672m8hsa-miR-193aAACUGGCCUACAAAGUCCCAG
hsa-miR-193bAACUGGCCCUCAAAGUCCCGCUUU
miR-203.13893951Ahsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-25/32/92/363/36743491Ahsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-274004071A,m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-284184251A,m8hsa-miR-28brainAAGGAGCUCACAGUCUAUUGAG
miR-3340471A,m8hsa-miR-33GUGCAUUGUAGUUGCAUUG
hsa-miR-33bGUGCAUUGCUGUUGCAUUGCA
miR-370191219181Ahsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
miR-376c1361431A,m8hsa-miR-376cAACAUAGAGGAAAUUCCACG
miR-378*3653721A,m8hsa-miR-422bCUGGACUUGGAGUCAGAAGGCC
hsa-miR-422aCUGGACUUAGGGUCAGAAGGCC
miR-382354360m8hsa-miR-382brainGAAGUUGUUCGUGGUGGAUUCG
miR-54320252031m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
miR-93693751Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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