Gene Page: MAG

Summary
GeneID  4099
Symbol  MAG
Synonyms  GMA|S-MAG|SIGLEC-4A|SIGLEC4A
Description  myelin associated glycoprotein
See related  HGNC:6783|MIM:159460|Ensembl:ENSG00000105695|HPRD:01160|
Locus tag  -
Gene type  protein-coding
Map location  19q13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0233 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SECISBP2L0.870.87
SPTLC20.870.83
FAR10.840.83
PTPN110.830.83
ITCH0.830.83
STRN0.820.83
CPD0.810.83
CDC42BPA0.810.84
TTLL70.810.82
ZFP1060.810.81
Top 10 negatively co-expressed genes
C1orf61-0.51-0.65
SERF2-0.46-0.53
IL32-0.46-0.50
RAB34-0.45-0.54
DBI-0.45-0.55
C16orf74-0.44-0.51
C1orf54-0.44-0.49
ENHO-0.44-0.51
DPM3-0.43-0.54
AF347015.21-0.43-0.43
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005529sugar bindingIEA-
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
COL1A1OI4collagen, type I, alpha 1Reconstituted ComplexBioGRID2446864 
COL2A1ANFH | AOM | COL11A3 | MGC131516 | SEDCcollagen, type II, alpha 1-HPRD,BioGRID2446864 
COL3A1EDS4A | FLJ34534collagen, type III, alpha 1-HPRD,BioGRID2446864 
COL4A1arrestencollagen, type IV, alpha 1Reconstituted ComplexBioGRID2446864 
COL5A1-collagen, type V, alpha 1Reconstituted ComplexBioGRID2446864 
COL6A1OPLLcollagen, type VI, alpha 1Reconstituted ComplexBioGRID2446864 
COL9A1DJ149L1.1.2 | EDM6 | FLJ40263 | MEDcollagen, type IX, alpha 1-HPRD,BioGRID2446864 
COL9A2DJ39G22.4 | EDM2 | MEDcollagen, type IX, alpha 2-HPRD2446864 
COL9A3DJ885L7.4.1 | EDM3 | FLJ90759 | IDD | MEDcollagen, type IX, alpha 3-HPRD2446864 
FN1CIG | DKFZp686F10164 | DKFZp686H0342 | DKFZp686I1370 | DKFZp686O13149 | ED-B | FINC | FN | FNZ | GFND | GFND2 | LETS | MSFfibronectin 1-HPRD11423128 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID7525550 
MAP1BDKFZp686E1099 | DKFZp686F1345 | FLJ38954 | FUTSCH | MAP5microtubule-associated protein 1B-HPRD,BioGRID11733546 
MBPMGC99675myelin basic protein-HPRD12237860 
NGFRCD271 | Gp80-LNGFR | TNFRSF16 | p75(NTR) | p75NTRnerve growth factor receptor (TNFR superfamily, member 16)-HPRD12011108 
PLP1MMPL | PLP | PLP/DM20 | PMD | SPG2proteolipid protein 1-HPRD12237860 
PRNPASCR | CD230 | CJD | GSS | MGC26679 | PRIP | PrP | PrP27-30 | PrP33-35C | PrPc | prionprion protein-HPRD15146195 
RTN4RNGR | NOGORreticulon 4 receptor-HPRD12089450 |12160746 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
PID_P75_NTR_PATHWAY 6951All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 9165All SZGR genes in this pathway
REACTOME_BASIGIN_INTERACTIONS 3023All SZGR genes in this pathway
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 8161All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
ROPERO_HDAC2_TARGETS 11471All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
PENG_LEUCINE_DEPRIVATION_UP 14293All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_UP 8959All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_DN 5443All SZGR genes in this pathway
LEIN_OLIGODENDROCYTE_MARKERS 7453All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway


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