Search results: The pahtway p881 has 81 genes in the original annotation. Currently, there are 61 genes in SZGR 2.0 (with evidence in schizophrenia) that are present at this pathway.

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Gene ID Symbol Synonyms Official Full Name Location SZ group ? Functional group ?
89846FGD3ZFYVE5FYVE, RhoGEF and PH domain containing 3-CV:GWASdb
CV:PGCnp
Expression
GO_Annotation
5599MAPK8JNK | JNK-46 | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1 | SAPK1cmitogen-activated protein kinase 810q11.22CV:PGCnp
DNM:Fromer_2014
Network
CompositeSet
22986SORCS3SORCSsortilin related VPS10 domain containing receptor 310q23-q25CV:PGCnp
GO_Annotation
7189TRAF6MGC:3310 | RNF85TNF receptor associated factor 611p12CV:PGCnp
GO_Annotation
Network
5970RELANFKB3 | p65v-rel avian reticuloendotheliosis viral oncogene homolog A11q13CV:PGCnp
DNM:Ambalavanan_2016
Network
PMID:cooccur
9828ARHGEF17P164RHOGEF | TEM4 | p164-RhoGEFRho guanine nucleotide exchange factor 1711q13.4CV:PGCnpCompositeSet
Darnell FMRP targets
23365ARHGEF12LARG | PRO2792Rho guanine nucleotide exchange factor 1211q23.3CV:PGCnp
DMG:Wockner_2014
GSMA_I
CompositeSet
Darnell FMRP targets
121512FGD4CMT4H | FRABP | ZFYVE6FYVE, RhoGEF and PH domain containing 412p11.21CV:GWASdb
CV:PGCnp
GO_Annotation
G2Cdb.humanNRC
G2Cdb.humanPSP
Potential synaptic genes
11108PRDM4PFM1PR domain 412q23.3CV:GWASdb
CV:PGCnp
4792NFKBIAIKBA | MAD-3 | NFKBINFKB inhibitor alpha14q13CV:GWASdb
CV:PGCnp
Network
6655SOS2NS9SOS Ras/Rho guanine nucleotide exchange factor 214q21CV:PGCnp
DNM:Gulsuner_2013
5663PSEN1AD3 | FAD | PS-1 | PS1 | S182presenilin 114q24.3CV:PGCnp
GO_Annotation
Network
PMID:cooccur
NEUROTROPHIN SIGNALING
83464APH1BAPH-1B | PRO1328 | PSFL | TAAV688aph-1 homolog B, gamma secretase subunit15q22.2CV:PGCnp
PMID:cooccur
NEUROTROPHIN SIGNALING
84894LINGO1LERN1 | LRRN6A | UNQ201leucine rich repeat and Ig domain containing 115q24.3CV:PGCnp
DMG:Wockner_2014
INTRACELLULAR SIGNAL TRANSDUCTION
CompositeSet
Darnell FMRP targets
11214AKAP13AKAP-13 | AKAP-Lbc | ARHGEF13 | BRX | HA-3 | Ht31 | LBC | PRKA13 | PROTO-LB | PROTO-LBC | c-lbc | p47A-kinase anchoring protein 1315q25.3CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
29ABRMDBactive BCR-related17p13.3CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
GO_Annotation
PMID:cooccur
CompositeSet
Darnell FMRP targets
7531YWHAE14-3-3E | HEL2 | KCIP-1 | MDCR | MDStyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon17p13.3Association
CV:PGCnp
Network
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_TAP-PSD-95-CORE
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Potential synaptic genes
4974OMGOMGPoligodendrocyte myelin glycoprotein17q11.2PMID:cooccurCELL ADHESION AND TRANSSYNAPTIC SIGNALING
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
CompositeSet
26574AATFBFR2 | CHE-1 | CHE1 | DEDapoptosis antagonizing transcription factor17q12CNV:YES
CV:PGCnp
DMG:Jaffe_2016
4804NGFRCD271 | Gp80-LNGFR | TNFRSF16 | p75(NTR) | p75NTRnerve growth factor receptor17q21-q22CV:PGCnp
GO_Annotation
PMID:cooccur
396ARHGDIAGDIA1 | HEL-S-47e | NPHS8 | RHOGDI | RHOGDI-1Rho GDP dissociation inhibitor (GDI) alpha17q25.3PMID:cooccurEXOCYTOSIS
CompositeSet
4099MAGGMA | S-MAG | SIGLEC-4A | SIGLEC4A | SPG75myelin associated glycoprotein19q13.1Association
CV:PGCnp
Network
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
55851PSENENMDS033 | MSTP064 | PEN-2 | PEN2presenilin enhancer gamma secretase subunit19q13.12DMG:Jaffe_2016
DMG:Wockner_2014
NEUROTROPHIN SIGNALING
64857PLEKHG2ARHGEF42 | CLG | LDAMDpleckstrin homology and RhoGEF domain containing G219q13.2CV:PGCnp
DMG:Jaffe_2016
4803NGFBeta-NGF | HSAN5 | NGFBnerve growth factor1p13.1CV:GWAScat
CV:GWASdb
CV:PGCnp
GO_Annotation
PMID:cooccur
10451VAV3-vav guanine nucleotide exchange factor 31p13.3CV:GWASdb
CV:PGCnp
DMG:Jaffe_2016
PMID:cooccur
3065HDAC1GON-10 | HD1 | RPD3 | RPD3L1histone deacetylase 11p34CV:PGCnp
PMID:cooccur
Ascano FMRP targets
Chromatin Remodeling Genes
51107APH1A6530402N02Rik | APH-1 | APH-1A | CGI-78aph-1 homolog A, gamma secretase subunit1p36.13-q31.3CV:PGCnp
DMG:Wockner_2014
GSMA_I
GSMA_IIA
PMID:cooccur
NEUROTROPHIN SIGNALING
9826ARHGEF11GTRAP48 | PDZ-RHOGEFRho guanine nucleotide exchange factor 111q21CV:PGCnp
DNM:Fromer_2014
GR_Ng
GSMA_I
GSMA_IIA
PMID:cooccur
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
Potential synaptic genes
9181ARHGEF2GEF | GEF-H1 | GEFH1 | LFP40 | P40Rho/Rac guanine nucleotide exchange factor 21q21-q22CV:PGCnp
DMG:Wockner_2014
GO_Annotation
GSMA_I
GSMA_IIA
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
84033OBSCNARHGEF30 | UNC89obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF1q42.13CV:PGCnp
DNM:Fromer_2014
Network
CompositeSet
5664PSEN2AD3L | AD4 | CMD1V | PS2 | STM2presenilin 21q42.13CV:PGCnp
Network
PMID:cooccur
NEUROTROPHIN SIGNALING
57580PREX1P-REX1phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 120q13.13CV:PGCnp
DMG:Wockner_2014
CompositeSet
Darnell FMRP targets
6453ITSN1ITSN | SH3D1A | SH3P17intersectin 121q22.1-q22.2CV:PGCnp
DNM:Fromer_2014
GO_Annotation
Network
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
CompositeSet
Darnell FMRP targets
Potential synaptic genes
7074TIAM1-T-cell lymphoma invasion and metastasis 121q22.11CV:PGCnp
GO_Annotation
Network
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
Potential synaptic genes
57142RTN4ASY | NI220/250 | NOGO | NOGO-A | NOGOC | NSP | NSP-CL | Nbla00271 | Nbla10545 | Nogo-B | Nogo-C | RTN-X | RTN4-A | RTN4-B1 | RTN4-B2 | RTN4-Creticulon 42p16.3Association
CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
GO_Annotation
GR_WM
PMID:cooccur
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
6868ADAM17ADAM18 | CD156B | CSVP | NISBD | NISBD1 | TACEADAM metallopeptidase domain 172p25CV:PGCnp
DMG:Jaffe_2016
Network
PMID:cooccur
10018BCL2L11BAM | BIM | BODBCL2 like 112q13CV:PGCnp
GSMA_I
GSMA_IIA
PMID:cooccur
50649ARHGEF4ASEF | ASEF1 | GEF4 | STM6Rho guanine nucleotide exchange factor 42q22CV:PGCnp
GSMA_I
GSMA_IIA
CompositeSet
Darnell FMRP targets
25791NGEFARHGEF27 | EPHEXINneuronal guanine nucleotide exchange factor2q37CV:GWAScat
CV:GWASdb
CV:PGCnp
CV:Ripke_2013
DMG:Jaffe_2016
GO_Annotation
LK:YES
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
50650ARHGEF3GEF3 | STA3 | XPLNRho guanine nucleotide exchange factor 33p14.3CV:PGCnp
DMG:Jaffe_2016
387RHOAARH12 | ARHA | RHO12 | RHOH12ras homolog family member A3p21.3CV:PGCnp
DMG:Wockner_2014
GO_Annotation
Network
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
Potential synaptic genes
4615MYD88MYD88Dmyeloid differentiation primary response 883p22CV:PGCnp
GSMA_I
PMID:cooccur
8997KALRNARHGEF24 | CHD5 | CHDS5 | DUET | DUO | HAPIP | TRADkalirin, RhoGEF kinase3q21.2CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
GO_Annotation
PMID:cooccur
G2Cdb.human_PocklingtonH1
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
Potential synaptic genes
1894ECT2ARHGEF31epithelial cell transforming 23q26.1-q26.2CV:PGCnp
836CASP3CPP32 | CPP32B | SCA-1caspase 34q34CV:PGCnp
DMG:Wockner_2014
GO_Annotation
Network
PMID:cooccur
7204TRIOARHGEF23 | tgattrio Rho guanine nucleotide exchange factor5p15.2CV:PGCnp
DMG:Wockner_2014
Network
PMID:cooccur
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
Ascano FMRP targets
5924RASGRF2GRF2 | RAS-GRF2Ras protein specific guanine nucleotide releasing factor 25q13CV:GWAScat
CV:PGCnp
PMID:cooccur
G2Cdb.humanPSD
G2Cdb.humanPSP
8841HDAC3HD3 | RPD3 | RPD3-2histone deacetylase 35q31GSMA_I
PMID:cooccur
Chromatin Remodeling Genes
8878SQSTM1A170 | FTDALS3 | OSIL | PDB3 | ZIP3 | p60 | p62 | p62Bsequestosome 15q35CV:PGCnp
DMG:Jaffe_2016
GSMA_IIA
Network
221472FGD2ZFYVE4FYVE, RhoGEF and PH domain containing 26p21.2CV:GWASdb
CV:PGCnp
DEG:Sanders_2013
GO_Annotation
GSMA_I
GSMA_IIE
3066HDAC2HD2 | RPD3 | YAF1histone deacetylase 26q21DMG:Wockner_2014
Network
PMID:cooccur
Chromatin Remodeling Genes
26230TIAM2STEF | TIAM-2T-cell lymphoma invasion and metastasis 26q25.2CV:PGCnp
DMG:Jaffe_2016
GO_Annotation
Ascano FMRP targets
5879RAC1MIG5 | Rac-1 | TC-25 | p21-Rac1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)7p22CV:PGCnp
DMG:Wockner_2014
Network
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_TAP-PSD-95-CORE
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Potential synaptic genes
835CASP2CASP-2 | ICH1 | NEDD-2 | NEDD2 | PPP1R57caspase 27q34-q35CV:PGCnp
3551IKBKBIKK-beta | IKK2 | IKKB | IMD15 | NFKBIKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta8p11.2CV:PGCnp
DMG:Wockner_2014
Network
8767RIPK2CARD3 | CARDIAK | CCK | GIG30 | RICK | RIP2receptor interacting serine/threonine kinase 28q21CV:PGCnp
DMG:Wockner_2014
Network
PMID:cooccur
23229ARHGEF9COLLYBISTIN | EIEE8 | HPEM-2 | PEM-2 | PEM2Cdc42 guanine nucleotide exchange factor 9Xq11.1CV:PGCnp
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
Potential synaptic genes
4168MCF2ARHGEF21 | DBLMCF.2 cell line derived transforming sequenceXq27CV:PGCnp
PMID:cooccur
Potential synaptic genes
393ARHGAP4C1 | RGC1 | RhoGAP4 | SrGAP4 | p115Rho GTPase activating protein 4Xq28CV:GWASdb
CV:PGCnp
DMG:vanEijk_2014
PMID:cooccur
3654IRAK1IRAK | pelleinterleukin 1 receptor associated kinase 1Xq28CV:PGCnp
Expression
Network
PMID:cooccur
Potential synaptic genes