Gene Page: AMOTL2

Summary
GeneID  51421
Symbol  AMOTL2
Synonyms  LCCP
Description  angiomotin like 2
See related  HGNC:17812|Ensembl:ENSG00000114019|HPRD:16485|
Locus tag  -
Gene type  protein-coding
Map location  3q21-q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0042802identical protein bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005923tight junctionIEABrain (GO term level: 10)-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AMOTL2LCCPangiomotin like 2Two-hybridBioGRID16189514 
FXR2FMR1L2fragile X mental retardation, autosomal homolog 2Two-hybridBioGRID16189514 
GCC1FLJ22035 | GCC1P | GCC88 | MGC20706GRIP and coiled-coil domain containing 1Two-hybridBioGRID16189514 
GNG11GNGT11guanine nucleotide binding protein (G protein), gamma 11Two-hybridBioGRID16189514 
KRT15CK15 | K15 | K1COkeratin 15Two-hybridBioGRID16189514 
KRT20CD20 | CK20 | K20 | KRT21 | MGC35423keratin 20Two-hybridBioGRID16189514 
MAD1L1HsMAD1 | MAD1 | PIG9 | TP53I9 | TXBP181MAD1 mitotic arrest deficient-like 1 (yeast)Two-hybridBioGRID16189514 
MAGOHBFLJ10292 | MGN2 | mago | magohmago-nashi homolog B (Drosophila)Two-hybridBioGRID16189514 
MPP1AAG12 | DXS552 | DXS552E | EMP55 | MRG1 | PEMPmembrane protein, palmitoylated 1, 55kDaTwo-hybridBioGRID16189514 
NDC80HEC | HEC1 | KNTC2 | TID3 | hsNDC80NDC80 homolog, kinetochore complex component (S. cerevisiae)Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_SIGNALING_BY_HIPPO 2215All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_DN 240171All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN 4834All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION 5031All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_UP 209139All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_ONLY_UP 3318All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
AMIT_EGF_RESPONSE_120_HELA 6947All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP 223140All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP 182119All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_UP 175116All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP 3427All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_DN 160101All SZGR genes in this pathway
BURTON_ADIPOGENESIS_9 9259All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G 9562All SZGR genes in this pathway
AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G 17196All SZGR genes in this pathway
LABBE_WNT3A_TARGETS_UP 11271All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
WONG_EMBRYONIC_STEM_CELL_CORE 335193All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 7646All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
WINZEN_DEGRADED_VIA_KHSRP 10070All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF 516308All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p158215891A,m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-14510331039m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-1499429491A,m8hsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
miR-150108310901A,m8hsa-miR-150UCUCCCAACCCUUGUACCAGUG
miR-182167816841Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-200bc/42917981804m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-22412761282m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-249559611Ahsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
hsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
miR-27166416701Ahsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-30-5p154615531A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-324-3p127312791Ahsa-miR-324-3pCCACUGCCCCAGGUGCUGCUGG
miR-3816386441Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-382160816151A,m8hsa-miR-382brainGAAGUUGUUCGUGGUGGAUUCG
miR-9168016861Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
miR-96167816841Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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