Gene Page: PFKP

Summary
GeneID  5214
Symbol  PFKP
Synonyms  FLJ40226|PFK-C|PFKF
Description  phosphofructokinase, platelet
See related  HGNC:8878|MIM:171840|Ensembl:ENSG00000067057|HPRD:01384|
Locus tag  RP11-298E9.2
Gene type  protein-coding
Map location  10p15.3-p15.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0069 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIEA-
GO:00038726-phosphofructokinase activityIEA-
GO:00038726-phosphofructokinase activityTAS1834056 
GO:0005515protein bindingIPI17353931 
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
GO:0016301kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006096glycolysisIEA-
GO:0006096glycolysisNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP6444721 
GO:0005737cytoplasmIEA-
GO:00059456-phosphofructokinase complexIEA-
GO:00059456-phosphofructokinase complexNAS-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DYNLL1DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1dynein, light chain, LC8-type 1-HPRD14760703 
MCCDKFZp762O1615 | FLJ38893 | FLJ46755 | MCC1mutated in colorectal cancersAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLYCOLYSIS_GLUCONEOGENESIS 6241All SZGR genes in this pathway
KEGG_PENTOSE_PHOSPHATE_PATHWAY 2714All SZGR genes in this pathway
KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 3423All SZGR genes in this pathway
KEGG_GALACTOSE_METABOLISM 2622All SZGR genes in this pathway
BIOCARTA_PTDINS_PATHWAY 2316All SZGR genes in this pathway
REACTOME_GLYCOLYSIS 2918All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_GLUCOSE_METABOLISM 6942All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN 5036All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_UP 430232All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
ELVIDGE_HYPOXIA_UP 171112All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_UP 13085All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_UP 215137All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN 172112All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP 176111All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_BULK_DN 2315All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
ALCALA_APOPTOSIS 8860All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP 195138All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_METASTASIS_DN 12165All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN 309206All SZGR genes in this pathway
SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP 4530All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION 8868All SZGR genes in this pathway
ABBUD_LIF_SIGNALING_2_UP 1413All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN 163115All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_UP 11484All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN 4826All SZGR genes in this pathway
CROMER_METASTASIS_DN 8158All SZGR genes in this pathway
BRUNO_HEMATOPOIESIS 6648All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C8 7256All SZGR genes in this pathway
KIM_HYPOXIA 2521All SZGR genes in this pathway
HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC 5032All SZGR genes in this pathway
HARRIS_HYPOXIA 8164All SZGR genes in this pathway
LEONARD_HYPOXIA 4735All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_UP 180125All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR 14984All SZGR genes in this pathway
HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 163113All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
SAFFORD_T_LYMPHOCYTE_ANERGY 8754All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
LIN_MELANOMA_COPY_NUMBER_DN 4134All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
RUIZ_TNC_TARGETS_DN 14279All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_UP 10575All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN 374217All SZGR genes in this pathway
QI_HYPOXIA 14096All SZGR genes in this pathway
WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 2821All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_UP 11265All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP 1512All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway
WACKER_HYPOXIA_TARGETS_OF_VHL 1311All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_DN 10971All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway


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