Gene Page: PRSS3

Summary
GeneID  5646
Symbol  PRSS3
Synonyms  MTG|PRSS4|TRY3|TRY4
Description  protease, serine, 3
See related  HGNC:9486|Ensembl:ENSG00000010438|HPRD:06685|
Locus tag  RP11-176F3.3
Gene type  protein-coding
Map location  9p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIDAglutamate (GO term level: 7)6698368 |14507909 
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0005509calcium ion bindingIDA6698368 
GO:0005515protein bindingIPI6698368 |14507909 
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIDA6698368 
GO:0006508proteolysisIEA-
GO:0006508proteolysisNAS8294000 
GO:0007586digestionTAS6698368 |14507909 
GO:0031638zymogen activationIDA6698368 
GO:0043542endothelial cell migrationIMP15313892 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceIDA6698368 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APPAAA | ABETA | ABPP | AD1 | APPI | CTFgamma | CVAP | PN2amyloid beta (A4) precursor protein-HPRD11827488 
TFPIEPI | LACI | TFI | TFPI1tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)-HPRD,BioGRID7498454 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
NAKAMURA_CANCER_MICROENVIRONMENT_UP 2614All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_UP 276187All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_DN 13870All SZGR genes in this pathway
JAEGER_METASTASIS_DN 258141All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP 175108All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_DN 214133All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_3_UP 329196All SZGR genes in this pathway
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP 8767All SZGR genes in this pathway
DORSEY_GAB2_TARGETS 3117All SZGR genes in this pathway
CROMER_METASTASIS_DN 8158All SZGR genes in this pathway
YAGI_AML_FAB_MARKERS 191131All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G4 2115All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN 312203All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_UP 2513All SZGR genes in this pathway
HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN 4831All SZGR genes in this pathway
LINDSTEDT_DENDRITIC_CELL_MATURATION_D 6844All SZGR genes in this pathway
WALLACE_JAK2_TARGETS_UP 2615All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G24 2819All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP 12170All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP 344215All SZGR genes in this pathway
NABA_ECM_REGULATORS 238125All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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