Gene Page: BCHE

Summary
GeneID  590
Symbol  BCHE
Synonyms  CHE1|E1
Description  butyrylcholinesterase
See related  HGNC:983|MIM:177400|Ensembl:ENSG00000114200|HPRD:01519|
Locus tag  -
Gene type  protein-coding
Map location  3q26.1-q26.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001540beta-amyloid bindingNAS11569538 
GO:0004104cholinesterase activityNAS-
GO:0004091carboxylesterase activityIEA-
GO:0016787hydrolase activityIEA-
GO:0019899enzyme bindingNAS11569538 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0050783cocaine metabolic processTAS8622553 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionNAS14718574 
GO:0005641nuclear envelope lumenIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCHECHE1 | E1butyrylcholinesteraseTwo-hybridBioGRID10529218 
COLQEADcollagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase-HPRD,BioGRID10529218 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DIABETES_PATHWAYS 13391All SZGR genes in this pathway
REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN 1611All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN 196131All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_UP 11668All SZGR genes in this pathway
MAHADEVAN_IMATINIB_RESISTANCE_DN 2011All SZGR genes in this pathway
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP 3618All SZGR genes in this pathway
SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP 7347All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_B 4822All SZGR genes in this pathway
NELSON_RESPONSE_TO_ANDROGEN_DN 1914All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_UP 2015All SZGR genes in this pathway
YEGNASUBRAMANIAN_PROSTATE_CANCER 12860All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP 181112All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
BRUECKNER_TARGETS_OF_MIRLET7A3_UP 11169All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP 14985All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
MIKKELSEN_NPC_ICP_WITH_H3K4ME3 445257All SZGR genes in this pathway
NIELSEN_GIST_VS_SYNOVIAL_SARCOMA_DN 2017All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-142-5p15211Ahsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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