| AATF | CHE-1 | CHE1 | DED | apoptosis antagonizing transcription factor | - | HPRD,BioGRID | 12847090 |
| AHR | - | aryl hydrocarbon receptor | - | HPRD,BioGRID | 10471301 |12612060
|
| AR | AIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFM | androgen receptor | Affinity Capture-Western | BioGRID | 15661808 |
| ARNT | HIF-1beta | HIF1B | HIF1BETA | TANGO | bHLHe2 | aryl hydrocarbon receptor nuclear translocator | Reconstituted Complex | BioGRID | 10471301 |
| ATF7IP | FLJ10139 | FLJ10688 | MCAF | p621 | activating transcription factor 7 interacting protein | MCAF1 interacts with Sp1. | BIND | 15691849 |
| ATF7IP2 | FLJ12668 | MCAF2 | activating transcription factor 7 interacting protein 2 | MCAF2 interacts with Sp1. | BIND | 15691849 |
| BCL6 | BCL5 | BCL6A | LAZ3 | ZBTB27 | ZNF51 | B-cell CLL/lymphoma 6 | - | HPRD | 12004059 |
| BRCA1 | BRCAI | BRCC1 | IRIS | PSCP | RNF53 | breast cancer 1, early onset | - | HPRD | 10720440 |
| BRCA1 interacts with Sp1. | BIND | 12706836 |
| Affinity Capture-Western | BioGRID | 12706836 |
| C14orf106 | FLJ11186 | HSA242977 | KIAA1903 | MIS18BP1 | chromosome 14 open reading frame 106 | - | HPRD | 10976766 |
| CD2 | SRBC | T11 | CD2 molecule | - | HPRD | 7933095 |
| CD209 | CDSIGN | CLEC4L | DC-SIGN | DC-SIGN1 | MGC129965 | CD209 molecule | Sp1 interacts with the CD209 promoter. | BIND | 15838506 |
| CDC25C | CDC25 | cell division cycle 25 homolog C (S. pombe) | Sp1 interacts with the cdc25c promoter. | BIND | 15574328 |
| CDKN1A | CAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | SP1 interacts with the CDKN1A (p21) promoter. | BIND | 15674334 |
| Sp1 interacts with CDKN1A promoter. | BIND | 15780936 |
| CEBPB | C/EBP-beta | CRP2 | IL6DBP | LAP | MGC32080 | NF-IL6 | TCF5 | CCAAT/enhancer binding protein (C/EBP), beta | - | HPRD,BioGRID | 12847250 |
| CLCN1 | CLC1 | MGC138361 | MGC142055 | chloride channel 1, skeletal muscle | p-CLCN1 interacts with Sp1. | BIND | 14657503 |
| DMPK | DM | DM1 | DM1PK | DMK | MDPK | MT-PK | dystrophia myotonica-protein kinase | Mutant DMPK mRNA interacts with Sp1. | BIND | 14657503 |
| E2F1 | E2F-1 | RBAP1 | RBBP3 | RBP3 | E2F transcription factor 1 | - | HPRD,BioGRID | 10547281 |
| E2F2 | E2F-2 | E2F transcription factor 2 | - | HPRD | 8657141 |8657142 |9694791 |
| E2F3 | DKFZp686C18211 | E2F-3 | KIAA0075 | MGC104598 | E2F transcription factor 3 | - | HPRD | 8657141 |
| EGR1 | AT225 | G0S30 | KROX-24 | NGFI-A | TIS8 | ZIF-268 | ZNF225 | early growth response 1 | Egr1 interacts with Sp1.This interaction was modelled on a demonstrated interaction between human Egr1 and mouse Sp1. | BIND | 12569082 |
| ELF1 | - | E74-like factor 1 (ets domain transcription factor) | - | HPRD,BioGRID | 10976766 |
| GABPA | E4TF1-60 | E4TF1A | NFT2 | NRF2 | NRF2A | GA binding protein transcription factor, alpha subunit 60kDa | - | HPRD,BioGRID | 11237613 |
| GATA1 | ERYF1 | GF-1 | GF1 | NFE1 | GATA binding protein 1 (globin transcription factor 1) | Reconstituted Complex | BioGRID | 12239153 |
| GRIN1 | NMDA1 | NMDAR1 | NR1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | - | HPRD | 14970236 |
| HCFC1 | CFF | HCF-1 | HCF1 | HFC1 | MGC70925 | VCAF | host cell factor C1 (VP16-accessory protein) | - | HPRD,BioGRID | 10976766 |12670868
|
| HDAC1 | DKFZp686H12203 | GON-10 | HD1 | RPD3 | RPD3L1 | histone deacetylase 1 | Affinity Capture-Western | BioGRID | 11896613 |12091390 |12176973 |12847090
|
| - | HPRD | 11896613 |11909966
|
| HDAC2 | RPD3 | YAF1 | histone deacetylase 2 | - | HPRD,BioGRID | 12151407 |
| HIF1A | HIF-1alpha | HIF1 | HIF1-ALPHA | MOP1 | PASD8 | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Sp1 interacts with HIF-1alpha. | BIND | 15780936 |
| HMGA1 | HMG-R | HMGA1A | HMGIY | MGC12816 | MGC4242 | MGC4854 | high mobility group AT-hook 1 | - | HPRD,BioGRID | 12665574 |
| HSPA8 | HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71 | heat shock 70kDa protein 8 | - | HPRD | 10976766 |
| HTT | HD | IT15 | huntingtin | - | HPRD,BioGRID | 11839795 |
| Huntingtin interacts with Sp1. This interaction was modelled on a demonstrated interaction between Huntingtin from human and Sp1 from rat. | BIND | 11839795 |
| JUN | AP-1 | AP1 | c-Jun | jun oncogene | - | HPRD,BioGRID | 10506225 |
| KLF10 | EGRA | TIEG | TIEG1 | Kruppel-like factor 10 | - | HPRD,BioGRID | 10976766 |
| KLF4 | EZF | GKLF | Kruppel-like factor 4 (gut) | - | HPRD,BioGRID | 9651398 |12034813
|
| KLF6 | BCD1 | COPEB | CPBP | DKFZp686N0199 | GBF | PAC1 | ST12 | ZF9 | Kruppel-like factor 6 | - | HPRD,BioGRID | 12433697 |
| LDB1 | CLIM2 | NLI | LIM domain binding 1 | Reconstituted Complex | BioGRID | 12239153 |
| LMO2 | RBTN2 | RBTNL1 | RHOM2 | TTG2 | LIM domain only 2 (rhombotin-like 1) | Reconstituted Complex | BioGRID | 12239153 |
| MDM2 | HDMX | MGC71221 | hdm2 | Mdm2 p53 binding protein homolog (mouse) | SP1 interacts with the MDM2 intronic promoter. | BIND | 15550242 |
| MEF2C | - | myocyte enhancer factor 2C | - | HPRD,BioGRID | 9748305 |
| MEF2D | DKFZp686I1536 | myocyte enhancer factor 2D | - | HPRD,BioGRID | 12213324 |
| MIER1 | DKFZp781G0451 | ER1 | KIAA1610 | MGC131940 | MGC150640 | MGC150641 | MI-ER1 | RP5-944N15.1 | hMI-ER1 | mesoderm induction early response 1 homolog (Xenopus laevis) | - | HPRD | 15117948 |
| MSX1 | HOX7 | HYD1 | msh homeobox 1 | - | HPRD,BioGRID | 10215616 |
| MYC | bHLHe39 | c-Myc | v-myc myelocytomatosis viral oncogene homolog (avian) | Myc interacts with Sp1. This interaction was modeled on a demonstrated interaction between mouse Myc and human Sp-1. | BIND | 11274368 |
| Sp1 interacts with Myc. | BIND | 15780936 |
| - | HPRD,BioGRID | 11274368 |
| MYOD1 | MYF3 | MYOD | PUM | bHLHc1 | myogenic differentiation 1 | - | HPRD,BioGRID | 10082523 |
| MYOG | MYF4 | MYOGENIN | bHLHc3 | myogenin (myogenic factor 4) | - | HPRD,BioGRID | 10082523 |
| NCL | C23 | FLJ45706 | nucleolin | Affinity Capture-Western | BioGRID | 14623863 |
| NFKB1 | DKFZp686C01211 | EBP-1 | KBF1 | MGC54151 | NF-kappa-B | NFKB-p105 | NFKB-p50 | p105 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Reconstituted Complex | BioGRID | 7933095 |
| NFKB2 | LYT-10 | LYT10 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | Reconstituted Complex | BioGRID | 7933095 |
| NOS3 | ECNOS | eNOS | nitric oxide synthase 3 (endothelial cell) | - | HPRD | 7541039 |
| NR2F1 | COUP-TFI | EAR-3 | EAR3 | ERBAL3 | NR2F2 | SVP44 | TCFCOUP1 | TFCOUP1 | nuclear receptor subfamily 2, group F, member 1 | - | HPRD,BioGRID | 9388268 |
| NR5A1 | AD4BP | ELP | FTZ1 | FTZF1 | SF-1 | SF1 | nuclear receptor subfamily 5, group A, member 1 | - | HPRD,BioGRID | 10919277 |
| PGR | NR3C3 | PR | progesterone receptor | Sp1 interacts with the PgRA promoter. | BIND | 15019994 |
| Sp1 interacts with the PgRB promoter. | BIND | 15019994 |
| PML | MYL | PP8675 | RNF71 | TRIM19 | promyelocytic leukemia | - | HPRD,BioGRID | 9819401 |
| POGZ | KIAA0461 | MGC71543 | SUHW5 | ZNF280E | ZNF635 | ZNF635m | pogo transposable element with ZNF domain | - | HPRD,BioGRID | 10976766 |
| POU2F1 | OCT1 | OTF1 | POU class 2 homeobox 1 | - | HPRD,BioGRID | 8668525 |
| PPP1R13L | IASPP | NKIP1 | RAI | protein phosphatase 1, regulatory (inhibitor) subunit 13 like | - | HPRD,BioGRID | 12134007 |
| PSIP1 | DFS70 | LEDGF | MGC74712 | PAIP | PSIP2 | p52 | p75 | PC4 and SFRS1 interacting protein 1 | Reconstituted Complex | BioGRID | 9885563 |
| PSMC5 | S8 | SUG1 | TBP10 | TRIP1 | p45 | p45/SUG | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | - | HPRD,BioGRID | 10816420 |
| PURA | PUR-ALPHA | PUR1 | PURALPHA | purine-rich element binding protein A | - | HPRD,BioGRID | 10457364 |
| RARA | NR1B1 | RAR | retinoic acid receptor, alpha | Reconstituted Complex | BioGRID | 10361124 |
| RB1 | OSRC | RB | p105-Rb | pRb | pp110 | retinoblastoma 1 | - | HPRD | 7732011 |
| Affinity Capture-Western | BioGRID | 11896613 |
| RBBP4 | NURF55 | RBAP48 | retinoblastoma binding protein 4 | - | HPRD,BioGRID | 12091390 |12943729
|
| RECQL4 | RECQ4 | RecQ protein-like 4 | SP1 interacts with the RECQL4 (RECQ4) promoter. | BIND | 15674334 |
| REL | C-Rel | v-rel reticuloendotheliosis viral oncogene homolog (avian) | - | HPRD,BioGRID | 7933095 |
| RELA | MGC131774 | NFKB3 | p65 | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | - | HPRD | 7933095|12055073 |
Affinity Capture-Western Reconstituted Complex | BioGRID | 7933095 |12055073
|
| RNASEN | DROSHA | ETOHI2 | HSA242976 | RANSE3L | RN3 | RNASE3L | ribonuclease type III, nuclear | - | HPRD | 10976766 |
| RNF4 | RES4-26 | SNURF | ring finger protein 4 | Affinity Capture-Western | BioGRID | 10617653 |
| RXRA | FLJ00280 | FLJ00318 | FLJ16020 | FLJ16733 | MGC102720 | NR2B1 | retinoid X receptor, alpha | Reconstituted Complex | BioGRID | 10361124 |
| SF3A1 | PRP21 | PRPF21 | SAP114 | SF3A120 | splicing factor 3a, subunit 1, 120kDa | - | HPRD | 10976766 |
| SHC1 | FLJ26504 | SHC | SHCA | SHC (Src homology 2 domain containing) transforming protein 1 | - | HPRD | 7933095 |
| SKIV2L2 | Dob1 | KIAA0052 | MGC142069 | Mtr4 | fSAP118 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | - | HPRD | 14676314 |
| SMAD2 | JV18 | JV18-1 | MADH2 | MADR2 | MGC22139 | MGC34440 | hMAD-2 | hSMAD2 | SMAD family member 2 | - | HPRD,BioGRID | 11114293 |
| SMAD3 | DKFZp586N0721 | DKFZp686J10186 | HSPC193 | HsT17436 | JV15-2 | MADH3 | MGC60396 | SMAD family member 3 | Affinity Capture-Western | BioGRID | 11114293 |11432852
|
| SMAD4 | DPC4 | JIP | MADH4 | SMAD family member 4 | - | HPRD | 11432852 |
| SMARCA4 | BAF190 | BRG1 | FLJ39786 | SNF2 | SNF2-BETA | SNF2L4 | SNF2LB | SWI2 | hSNF2b | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Reconstituted Complex | BioGRID | 11018012 |
| SMARCC1 | BAF155 | CRACC1 | Rsc8 | SRG3 | SWI3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | Reconstituted Complex | BioGRID | 11018012 |
| SMARCC2 | BAF170 | CRACC2 | Rsc8 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | Reconstituted Complex | BioGRID | 11018012 |
| SP3 | DKFZp686O1631 | SPR-2 | Sp3 transcription factor | - | HPRD | 9329821 |
| SP4 | HF1B | MGC130008 | MGC130009 | SPR-1 | Sp4 transcription factor | - | HPRD,BioGRID | 7559627 |
| SREBF1 | SREBP-1c | SREBP1 | bHLHd1 | sterol regulatory element binding transcription factor 1 | - | HPRD,BioGRID | 10224053 |
| SREBF2 | SREBP2 | bHLHd2 | sterol regulatory element binding transcription factor 2 | - | HPRD,BioGRID | 10976766 |
| SRF | MCM1 | serum response factor (c-fos serum response element-binding transcription factor) | Reconstituted Complex | BioGRID | 10082523 |
| SUB1 | MGC102747 | P15 | PC4 | p14 | SUB1 homolog (S. cerevisiae) | Reconstituted Complex | BioGRID | 9885563 |
| TAF4 | FLJ41943 | TAF2C | TAF2C1 | TAF4A | TAFII130 | TAFII135 | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | - | HPRD,BioGRID | 9742090 |
| TAL1 | SCL | TCL5 | bHLHa17 | tal-1 | T-cell acute lymphocytic leukemia 1 | - | HPRD,BioGRID | 12239153 |
| TNFSF10 | APO2L | Apo-2L | CD253 | TL2 | TRAIL | tumor necrosis factor (ligand) superfamily, member 10 | SP1 interacts with the TNFSF10 promoter. | BIND | 15619633 |
| TP53 | FLJ92943 | LFS1 | TRP53 | p53 | tumor protein p53 | p53 interacts with Sp1. | BIND | 15574328 |
| p53 interacts with Sp1. | BIND | 9492043 |
| TP53 (p53) interacts with Sp1. | BIND | 9685344 |
| TP53 (p53) interacts with SP1. | BIND | 15674334 |
| YY1 | DELTA | INO80S | NF-E1 | UCRBP | YIN-YANG-1 | YY1 transcription factor | Affinity Capture-Western | BioGRID | 10224053 |
| YY1 interacts with Sp1. | BIND | 8327494 |
| ZBTB16 | PLZF | ZNF145 | zinc finger and BTB domain containing 16 | - | HPRD | 12004059 |
| ZBTB7A | DKFZp547O146 | FBI-1 | FBI1 | LRF | MGC99631 | ZBTB7 | ZNF857A | pokemon | zinc finger and BTB domain containing 7A | - | HPRD | 12004059 |