Gene Page: TPM2

Summary
GeneID  7169
Symbol  TPM2
Synonyms  AMCD1|DA1|DA2B|TMSB
Description  tropomyosin 2 (beta)
See related  HGNC:12011|MIM:190990|Ensembl:ENSG00000198467|HPRD:11768|
Locus tag  RP11-112J3.4
Gene type  protein-coding
Map location  9p13.2-p13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0044 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIDA17194691 
GO:0008307structural constituent of muscleTAS7606936 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0043462regulation of ATPase activityIDA17194691 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIEA-
GO:0005862muscle thin filament tropomyosinTAS7606936 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTBPS1TP5BP1actin, beta-HPRD9108196 
JUNAP-1 | AP1 | c-Junjun oncogene-HPRD1631061 
PDLIM7LMP1PDZ and LIM domain 7 (enigma)-HPRD,BioGRID10359609 
RRADRAD | RAD1 | REM3Ras-related associated with diabetes-HPRD,BioGRID8557685 
S100A2CAN19 | MGC111539 | S100LS100 calcium binding protein A2-HPRD9092943 
S100A418A2 | 42A | CAPL | FSP1 | MTS1 | P9KA | PEL98S100 calcium binding protein A4-HPRD8120097 
TPM1C15orf13 | CMD1Y | HTM-alpha | TMSAtropomyosin 1 (alpha)-HPRD,BioGRID3857586 |7568216 
TPM2AMCD1 | DA1 | DA2B | TMSBtropomyosin 2 (beta)-HPRD,BioGRID1304342 |3857586 
|7568216 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CARDIAC_MUSCLE_CONTRACTION 8051All SZGR genes in this pathway
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 8565All SZGR genes in this pathway
KEGG_DILATED_CARDIOMYOPATHY 9268All SZGR genes in this pathway
REACTOME_STRIATED_MUSCLE_CONTRACTION 2712All SZGR genes in this pathway
REACTOME_MUSCLE_CONTRACTION 4824All SZGR genes in this pathway
REACTOME_SMOOTH_MUSCLE_CONTRACTION 2514All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN 169118All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN 335193All SZGR genes in this pathway
PROVENZANI_METASTASIS_UP 194112All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_UP 11668All SZGR genes in this pathway
LUI_THYROID_CANCER_PAX8_PPARG_UP 4429All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP 169127All SZGR genes in this pathway
MAHADEVAN_GIST_MORPHOLOGICAL_SWITCH 1511All SZGR genes in this pathway
HUMMERICH_SKIN_CANCER_PROGRESSION_DN 10064All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_2 4231All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
TOMLINS_PROSTATE_CANCER_DN 4033All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_F 5432All SZGR genes in this pathway
WU_CELL_MIGRATION 184114All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
LEE_LIVER_CANCER_ACOX1_DN 6539All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_UP 4936All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP 8767All SZGR genes in this pathway
HASLINGER_B_CLL_WITH_13Q14_DELETION 2418All SZGR genes in this pathway
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN 162102All SZGR genes in this pathway
YAGI_AML_SURVIVAL 12987All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_24HR_DN 148102All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
NATSUME_RESPONSE_TO_INTERFERON_BETA_DN 5233All SZGR genes in this pathway
ZHU_CMV_24_HR_DN 9164All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
KUNINGER_IGF1_VS_PDGFB_TARGETS_UP 8251All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP 7747All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
CHANG_CORE_SERUM_RESPONSE_UP 212128All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP 298174All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K27ME3 269159All SZGR genes in this pathway
CROONQUIST_STROMAL_STIMULATION_UP 6042All SZGR genes in this pathway
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN 9965All SZGR genes in this pathway
VALK_AML_CLUSTER_10 3322All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN 13483All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_UP 10575All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
SASSON_RESPONSE_TO_GONADOTROPHINS_DN 8766All SZGR genes in this pathway
SASSON_RESPONSE_TO_FORSKOLIN_DN 8868All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_2HR_DN 4933All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN 10367All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_DN 213127All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
PASINI_SUZ12_TARGETS_DN 315215All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
DELACROIX_RAR_TARGETS_DN 2416All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway
CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP 3516All SZGR genes in this pathway


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