Gene Page: CCKAR

Summary
GeneID  886
Symbol  CCKAR
Synonyms  CCK-A|CCK1-R|CCKRA
Description  cholecystokinin A receptor
See related  HGNC:1570|MIM:118444|Ensembl:ENSG00000163394|HPRD:00322|
Locus tag  -
Gene type  protein-coding
Map location  4p15.1-p15.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PRC10.960.75
ZWINT0.960.78
AURKA0.950.69
NUSAP10.950.59
KIF4A0.950.62
BUB10.950.59
CCNB20.950.53
BIRC50.940.55
RAD510.940.63
KIF2C0.940.57
Top 10 negatively co-expressed genes
AF347015.27-0.44-0.61
AF347015.8-0.44-0.63
AF347015.15-0.44-0.63
MT-CYB-0.44-0.61
AF347015.31-0.44-0.59
AF347015.33-0.44-0.60
MT-CO2-0.43-0.59
AF347015.2-0.43-0.62
AF347015.26-0.42-0.62
AF347015.9-0.40-0.55
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004951cholecystokinin receptor activityTAS8343165 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007409axonogenesisIEAneuron, axon, neurite (GO term level: 12)-
GO:0001764neuron migrationIEAneuron (GO term level: 8)-
GO:0030900forebrain developmentIEABrain (GO term level: 8)-
GO:0007200G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)TAS8343165 
GO:0007204elevation of cytosolic calcium ion concentrationTAS8503909 
GO:0007165signal transductionIEA-
GO:0007631feeding behaviorTAS8503909 
GO:0007586digestionTAS8503909 
GO:0007584response to nutrientTAS8503909 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneTAS8343165 
GO:0005887integral to plasma membraneTAS8343165 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCKMGC117187cholecystokinin-HPRD9006937 |9603948 
|10400673 |10595537 
|11300760 
in vitro
in vivo
Protein-peptide		BioGRID9006937 |9603948 
|10400673 |11300760 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CALCIUM_SIGNALING_PATHWAY 178134All SZGR genes in this pathway
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
ODONNELL_METASTASIS_DN 2413All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 419273All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_UP 3920All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_A 182108All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


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