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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CCNT2

Summary

GeneID

905

Symbol

CCNT2

Synonyms

FLJ90560|MGC134840

Description

cyclin T2

Locus tag

Gene type

protein-coding

Map location

2q21.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.023

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.02395

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IDA

16109376

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000079

regulation of cyclin-dependent protein kinase activity

TAS

9499409

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

GO:0006366

transcription from RNA polymerase II promoter

TAS

9499409

GO:0007049

cell cycle

IEA

GO:0051301

cell division

IEA

GO:0044419

interspecies interaction between organisms

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IDA

16109376

GO:0005654

nucleoplasm

EXP

12676794

GO:0005730

nucleolus

IDA

18029348

GO:0005737

cytoplasm

IDA

18029348

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CDK9	C-2k \| CDC2L4 \| CTK1 \| PITALRE \| TAK	cyclin-dependent kinase 9	CyclinT2b interacts with Cdk9.	BIND	9499409
			CyclinT2a interacts with Cdk9.	BIND	9499409
			-	HPRD,BioGRID	9499409\|10465067
			-	HPRD	10465067
HEXIM1	CLP1 \| EDG1 \| FLJ13562 \| HIS1 \| MAQ1	hexamethylene bis-acetamide inducible 1	-	HPRD,BioGRID	12832472
RB1	OSRC \| RB \| p105-Rb \| pRb \| pp110	retinoblastoma 1	-	HPRD,BioGRID	12037672

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION	27	17	All SZGR genes in this pathway
REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER	38	26	All SZGR genes in this pathway
REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	352	181	All SZGR genes in this pathway
REACTOME_RNA_POL_II_TRANSCRIPTION	105	54	All SZGR genes in this pathway
REACTOME_TRANSCRIPTION	210	127	All SZGR genes in this pathway
REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_	45	19	All SZGR genes in this pathway
REACTOME_ELONGATION_ARREST_AND_RECOVERY	32	14	All SZGR genes in this pathway
REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS	61	32	All SZGR genes in this pathway
REACTOME_HIV_INFECTION	207	122	All SZGR genes in this pathway
REACTOME_HIV_LIFE_CYCLE	125	69	All SZGR genes in this pathway
REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE	104	61	All SZGR genes in this pathway
REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	63	42	All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN	634	384	All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP	530	342	All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP	239	157	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_UP	28	16	All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	514	319	All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK	1652	1023	All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK	1442	892	All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP	769	437	All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	811	508	All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G3	15	10	All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP	244	151	All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS	217	138	All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP	439	257	All SZGR genes in this pathway
CHEN_HOXA5_TARGETS_9HR_UP	223	132	All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN	457	302	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN	254	158	All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	1080	713	All SZGR genes in this pathway
KOHOUTEK_CCNT2_TARGETS	58	35	All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY	1839	928	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	2000	2006	1A	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-142-3p	974	981	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-142-5p	561	567	m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-144	2000	2006	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-15/16/195/424/497	125	131	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-17-5p/20/93.mr/106/519.d	609	615	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-186	2321	2328	1A,m8	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-188	428	435	1A,m8	hsa-miR-188	CAUCCCUUGCAUGGUGGAGGGU
miR-19	1292	1299	1A,m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	1292	1299	1A,m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-192/215	11	18	1A,m8	hsa-miR-192	CUGACCUAUGAAUUGACAGCC
miR-192/215	11	18	1A,m8	hsa-miR-215	AUGACCUAUGAAUUGACAGAC
miR-193	1635	1641	1A	hsa-miR-193a	AACUGGCCUACAAAGUCCCAG
miR-193	1635	1641	1A	hsa-miR-193b	AACUGGCCCUCAAAGUCCCGCUUU
miR-204/211	427	433	m8	hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
miR-204/211	427	433	m8	hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
miR-223	445	451	1A	hsa-miR-223	UGUCAGUUUGUCAAAUACCCC
miR-23	822	828	1A	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
				hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
				hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
				hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
				hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
				hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-29	2200	2207	1A,m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-299-3p	181	187	1A	hsa-miR-299-3p	UAUGUGGGAUGGUAAACCGCUU
miR-30-5p	807	813	1A	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
				hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-323	2099	2105	1A	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-335	816	822	1A	hsa-miR-335^brain	UCAAGAGCAAUAACGAAAAAUGU
miR-378	1224	1230	1A	hsa-miR-378	CUCCUGACUCCAGGUCCUGUGU
miR-381	396	402	m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-493-5p	477	483	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-495	1527	1533	1A	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-543	1681	1687	1A	hsa-miR-543	AAACAUUCGCGGUGCACUUCU
miR-7	1106	1112	m8	hsa-miR-7^SZ	UGGAAGACUAGUGAUUUUGUUG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.