Gene Page: FOXP2

Summary
GeneID  93986
Symbol  FOXP2
Synonyms  CAGH44|DKFZp686H1726|SPCH1|TNRC10
Description  forkhead box P2
See related  HGNC:13875|MIM:605317|Ensembl:ENSG00000128573|HPRD:05611|
Locus tag  -
Gene type  protein-coding
Map location  7q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0042803protein homodimerization activityIDA16407075 
GO:0046872metal ion bindingIEA-
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0021758putamen developmentIMPBrain (GO term level: 12)11872605 
GO:0021757caudate nucleus developmentIMPneuron, Brain (GO term level: 12)11872605 
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CTBP1BARS | MGC104684C-terminal binding protein 1Affinity Capture-Western
Two-hybrid		BioGRID14701752 
FOXP112CC4 | FLJ23741 | HSPC215 | MGC12942 | MGC88572 | MGC99551 | QRF1 | hFKH1Bforkhead box P1-HPRD,BioGRID14701752 
FOXP2CAGH44 | DKFZp686H1726 | SPCH1 | TNRC10forkhead box P2Affinity Capture-WesternBioGRID14701752 
FOXP4FLJ40908 | FLJ44184 | hFKHLAforkhead box P4-HPRD,BioGRID14701752 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 408247All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP 485293All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LPS_UP 431237All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP 283177All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER 2219All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-12254601Ahsa-miR-122aUGGAGUGUGACAAUGGUGUUUGU
miR-12887931Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-19032391A,m8hsa-miR-190UGAUAUGUUUGAUAUAUUAGGU
miR-278793m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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