Gene Page: SEC22B

Summary
GeneID  9554
Symbol  SEC22B
Synonyms  ERS-24|SEC22L1
Description  SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
See related  HGNC:10700|MIM:604029|HPRD:04939|
Locus tag  -
Gene type  protein-coding
Map location  1q21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DYRK1A0.970.97
ADNP20.960.97
FOXJ30.950.96
AP003115.10.950.97
POLR3A0.950.96
PDE120.950.95
FAM115A0.950.97
USP220.950.97
AP1G10.950.96
NUP1530.940.97
Top 10 negatively co-expressed genes
FXYD1-0.80-0.86
MT-CO2-0.79-0.86
AF347015.31-0.79-0.85
HIGD1B-0.76-0.86
AF347015.33-0.76-0.81
S100B-0.76-0.82
IFI27-0.75-0.82
AC021016.1-0.75-0.82
AF347015.8-0.74-0.84
MT-CYB-0.74-0.81
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15272311 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006888ER to Golgi vesicle-mediated transportTAS9094723 
GO:0016192vesicle-mediated transportIEA-
GO:0015031protein transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0033116ER-Golgi intermediate compartment membraneIEA-
GO:0042470melanosomeIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
STX18DKFZp686O15149 | Ufe1syntaxin 18Affinity Capture-MS
Affinity Capture-Western		BioGRID15029241 
STX5SED5 | STX5Asyntaxin 5-HPRD11035026 
Affinity Capture-WesternBioGRID15029241 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 3825All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_UP 7848All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP 13784All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 206136All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
CHEOK_RESPONSE_TO_HD_MTX_DN 2418All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
HADDAD_B_LYMPHOCYTE_PROGENITOR 293193All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP 6440All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/206455461m8hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-196216271Ahsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-235305361Ahsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-37854601Ahsa-miR-378CUCCUGACUCCAGGUCCUGUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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