Gene Page: EIF1B

Summary
GeneID  10289
Symbol  EIF1B
Synonyms  GC20
Description  eukaryotic translation initiation factor 1B
See related  HGNC:30792|Ensembl:ENSG00000114784|HPRD:17032|
Locus tag  -
Gene type  protein-coding
Map location  3p22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.059 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003743translation initiation factor activityIEA-
GO:0005515protein bindingIPI17353931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006446regulation of translational initiationTAS7904817 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACAT1ACAT | MAT | T2 | THILacetyl-Coenzyme A acetyltransferase 1Affinity Capture-MSBioGRID17353931 
ACTR3ARP3ARP3 actin-related protein 3 homolog (yeast)Affinity Capture-MSBioGRID17353931 
EIF2S1EIF-2 | EIF-2A | EIF-2alpha | EIF2 | EIF2Aeukaryotic translation initiation factor 2, subunit 1 alpha, 35kDaAffinity Capture-MSBioGRID17353931 
EIF2S3EIF2 | EIF2G | EIF2gamma | eIF-2gAeukaryotic translation initiation factor 2, subunit 3 gamma, 52kDaAffinity Capture-MSBioGRID17353931 
EIF3AEIF3 | EIF3S10 | KIAA0139 | P167 | TIF32 | eIF3-p170 | eIF3-theta | p180 | p185eukaryotic translation initiation factor 3, subunit AAffinity Capture-MSBioGRID17353931 
EIF3DEIF3S7 | MGC126526 | MGC17258 | eIF3-p66 | eIF3-zetaeukaryotic translation initiation factor 3, subunit DAffinity Capture-MSBioGRID17353931 
EIF3EEIF3-P48 | EIF3S6 | INT6 | eIF3-p46eukaryotic translation initiation factor 3, subunit EAffinity Capture-MSBioGRID17353931 
EIF3EIPEIF3S11 | EIF3S6IP | HSPC021 | HSPC025 | MSTP005eukaryotic translation initiation factor 3, subunit E interacting proteinAffinity Capture-MSBioGRID17353931 
EIF3FEIF3S5 | eIF3-p47eukaryotic translation initiation factor 3, subunit FAffinity Capture-MSBioGRID17353931 
EIF3GEIF3-P42 | EIF3S4 | eIF3-delta | eIF3-p44eukaryotic translation initiation factor 3, subunit GAffinity Capture-MSBioGRID17353931 
EIF3HEIF3S3 | MGC102958 | eIF3-gamma | eIF3-p40eukaryotic translation initiation factor 3, subunit HAffinity Capture-MSBioGRID17353931 
EIF3IEIF3S2 | PRO2242 | TRIP-1 | TRIP1 | eIF3-beta | eIF3-p36eukaryotic translation initiation factor 3, subunit IAffinity Capture-MSBioGRID17353931 
EIF3KARG134 | EIF3-p28 | EIF3S12 | HSPC029 | M9 | MSTP001 | PLAC-24 | PLAC24 | PRO1474 | PTD001eukaryotic translation initiation factor 3, subunit KAffinity Capture-MSBioGRID17353931 
EIF3MB5 | FLJ29030 | GA17 | PCID1 | hfl-B5eukaryotic translation initiation factor 3, subunit MAffinity Capture-MSBioGRID17353931 
ERHDROER | FLJ27340enhancer of rudimentary homolog (Drosophila)Affinity Capture-MSBioGRID17353931 
HPRT1HGPRT | HPRThypoxanthine phosphoribosyltransferase 1Affinity Capture-MSBioGRID17353931 
MRCL3MLCB | MRLC3myosin regulatory light chain MRCL3Affinity Capture-MSBioGRID17353931 
PCMT1-protein-L-isoaspartate (D-aspartate) O-methyltransferaseAffinity Capture-MSBioGRID17353931 
RAB7AFLJ20819 | PRO2706 | RAB7RAB7A, member RAS oncogene familyAffinity Capture-MSBioGRID17353931 
RPA3REPA3replication protein A3, 14kDaAffinity Capture-MSBioGRID17353931 
RPS11-ribosomal protein S11Affinity Capture-MSBioGRID17353931 
RPS29-ribosomal protein S29Affinity Capture-MSBioGRID17353931 
RPS3AFTE1 | MFTL | MGC23240ribosomal protein S3AAffinity Capture-MSBioGRID17353931 
RPS9-ribosomal protein S9Affinity Capture-MSBioGRID17353931 
SHMT2GLYA | SHMTserine hydroxymethyltransferase 2 (mitochondrial)Affinity Capture-MSBioGRID17353931 
TAGLN2HA1756 | KIAA0120transgelin 2Affinity Capture-MSBioGRID17353931 
TCEB1SIIItranscription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)Affinity Capture-MSBioGRID17353931 
TSR1FLJ10534 | KIAA1401 | MGC131829TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)Affinity Capture-MSBioGRID17353931 
YARSCMTDIC | TYRRS | YRS | YTStyrosyl-tRNA synthetaseAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
BIDUS_METASTASIS_DN 16193All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_DN 11078All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN 12179All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_DN 169112All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
HU_GENOTOXIC_DAMAGE_24HR 3522All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_MUSCLE_DN 5128All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_UP 245159All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10 6938All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP 242159All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-299-5p3043101Ahsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
miR-494223229m8hsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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