Gene Page: SYNCRIP

Summary
GeneID  10492
Symbol  SYNCRIP
Synonyms  GRY-RBP|HNRPQ1|NSAP1|RP1-3J17.2|dJ3J17.2|hnRNP-Q|pp68
Description  synaptotagmin binding, cytoplasmic RNA interacting protein
See related  HGNC:16918|Ensembl:ENSG00000135316|HPRD:06734|
Locus tag  -
Gene type  protein-coding
Map location  6q14-q15
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003723RNA bindingTAS9847309 
GO:0005515protein bindingIPI12674497 |17353931 
GO:0008143poly(A) bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006397mRNA processingIEA-
GO:0008380RNA splicingTAS9847309 
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005792microsomeIEA-
GO:0005634nucleusTAS9847309 
GO:0005681spliceosomeIEA-
GO:0005737cytoplasmIEA-
GO:0005783endoplasmic reticulumIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
A1CFACF | ACF64 | ACF65 | APOBEC1CF | ASP | MGC163391 | RP11-564C4.2APOBEC1 complementation factor-HPRD,BioGRID11134005 |11352648 
APOBEC1APOBEC-1 | BEDP | CDAR1 | HEPRapolipoprotein B mRNA editing enzyme, catalytic polypeptide 1Reconstituted Complex
Two-hybrid		BioGRID11352648 
CNBPCNBP1 | DM2 | FLJ11631 | PROMM | RNF163 | ZCCHC22 | ZNF9CCHC-type zinc finger, nucleic acid binding proteinAffinity Capture-MSBioGRID17353931 
EPRSDKFZp313B047 | EARS | GLUPRORS | PARS | PIG32 | QARS | QPRSglutamyl-prolyl-tRNA synthetaseNSAP-1 interacts with GluProRS.BIND15479637 
GAPDHG3PD | GAPD | MGC88685glyceraldehyde-3-phosphate dehydrogenaseNSAP-1 interacts with GAPDH.BIND15479637 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Reconstituted ComplexBioGRID9341187 
HNRNPABABBP1 | FLJ40338 | HNRPABheterogeneous nuclear ribonucleoprotein A/B-HPRD11352648 
INSRCD220 | HHF5insulin receptor-HPRD,BioGRID11994298 
MGC34774-ribosomal protein L13A pseudogeneNSAP-1 interacts with L13a.BIND15479637 
PLCG1PLC-II | PLC1 | PLC148 | PLCgamma1phospholipase C, gamma 1Reconstituted ComplexBioGRID9341187 
PRKRADYT16 | HSD14 | PACT | RAXprotein kinase, interferon-inducible double stranded RNA dependent activatorAffinity Capture-MSBioGRID17353931 
PRMT1ANM1 | HCP1 | HRMT1L2 | IR1B4protein arginine methyltransferase 1Biochemical ActivityBioGRID12183049 
PTPN11BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2protein tyrosine phosphatase, non-receptor type 11Two-hybridBioGRID9847309 
PUF60FIR | FLJ31379 | RoBPI | SIAHBP1poly-U binding splicing factor 60KDaAffinity Capture-MSBioGRID17353931 
SMN1BCD541 | SMA | SMA1 | SMA2 | SMA3 | SMA4 | SMA@ | SMN | SMNT | T-BCD541survival of motor neuron 1, telomeric-HPRD11773003 
STK24MST-3 | MST3 | MST3B | STE20 | STK3serine/threonine kinase 24 (STE20 homolog, yeast)Affinity Capture-MSBioGRID17353931 
SYT1DKFZp781D2042 | P65 | SVP65 | SYTsynaptotagmin I-HPRD,BioGRID10734137 
SYT11DKFZp781D015 | KIAA0080 | MGC10881 | MGC17226 | SYT12synaptotagmin XI-HPRD10734137 
SYT2SytIIsynaptotagmin II-HPRD,BioGRID10734137 
SYT3DKFZp761O132 | SytIIIsynaptotagmin IIIReconstituted ComplexBioGRID10734137 
SYT4HsT1192 | KIAA1342synaptotagmin IV-HPRD,BioGRID10734137 
SYT5-synaptotagmin V-HPRD10734137 
SYT7IPCA-7 | MGC150517 | PCANAP7 | SYT-VIIsynaptotagmin VII-HPRD,BioGRID10734137 
SYT8DKFZp434K0322synaptotagmin VIIIAffinity Capture-Western
Reconstituted Complex		BioGRID10734137 
SYT9FLJ45896synaptotagmin IX-HPRD,BioGRID10734137 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NAKAMURA_CANCER_MICROENVIRONMENT_DN 4629All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP 285181All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 408247All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_DN 209122All SZGR genes in this pathway
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP 181101All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN 11671All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL 330217All SZGR genes in this pathway
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL 330215All SZGR genes in this pathway
SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN 4734All SZGR genes in this pathway
YANG_BREAST_CANCER_ESR1_LASER_DN 5038All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP 16792All SZGR genes in this pathway
LIU_COMMON_CANCER_GENES 7947All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP 176115All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN 165104All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
GEORGES_TARGETS_OF_MIR192_AND_MIR215 893528All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_DN 169102All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_DN 185111All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_METASTASIS_DN 12165All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 151100All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 5135All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_DN 245154All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
HEDENFALK_BREAST_CANCER_BRACX_DN 2014All SZGR genes in this pathway
HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR 5538All SZGR genes in this pathway
HU_GENOTOXIC_DAMAGE_4HR 3528All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP 425253All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP 285167All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_DN 277166All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_12HR_DN 3325All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_24HR_UP 126All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_32HR_DN 3928All SZGR genes in this pathway
DORN_ADENOVIRUS_INFECTION_48HR_DN 4029All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 14386All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_M_G1 14895All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_UP 12778All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN 10367All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
IKEDA_MIR1_TARGETS_UP 5339All SZGR genes in this pathway
JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN 9260All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_UP 279155All SZGR genes in this pathway
RAO_BOUND_BY_SALL4 227149All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-3751391461A,m8hsa-miR-375UUUGUUCGUUCGGCUCGCGUGA
miR-381365371m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-3823933991Ahsa-miR-382brainGAAGUUGUUCGUGGUGGAUUCG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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