Gene Page: TRAF3IP2

Summary
GeneID  10758
Symbol  TRAF3IP2
Synonyms  ACT1|C6orf2|C6orf4|C6orf5|C6orf6|CIKS|DKFZp586G0522|MGC3581
Description  TRAF3 interacting protein 2
See related  HGNC:1343|MIM:607043|Ensembl:ENSG00000056972|HPRD:06129|
Locus tag  -
Gene type  protein-coding
Map location  6q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
APH1A0.910.88
PPP4C0.910.91
TARBP20.900.93
SPNS10.900.86
TSEN340.900.90
LMAN20.900.90
HN10.900.91
RPN20.900.91
MAGED10.890.91
DULLARD0.890.91
Top 10 negatively co-expressed genes
AF347015.27-0.74-0.85
AF347015.33-0.73-0.86
MT-CO2-0.73-0.84
MT-CYB-0.73-0.86
AF347015.8-0.72-0.86
AF347015.31-0.72-0.82
AF347015.15-0.71-0.85
AF347015.2-0.70-0.86
HLA-F-0.69-0.73
AF347015.26-0.68-0.85
Gene Ontology
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007242intracellular signaling cascadeNAS10962033 
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIEP12761501 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD40Bp50 | CDW40 | MGC9013 | TNFRSF5 | p50CD40 molecule, TNF receptor superfamily member 5-HPRD,BioGRID12089335 
CHUKIKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16conserved helix-loop-helix ubiquitous kinase-HPRD,BioGRID10962033 
IKBKBFLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta-HPRD,BioGRID10962033 
IKBKGAMCBX1 | FIP-3 | FIP3 | Fip3p | IKK-gamma | IP | IP1 | IP2 | IPD2 | NEMOinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gammaAn unspecified isoform of CIKS interacts with IKK-gamma. This interaction was modeled on a demonstrated interaction between CIKS from an unspecified species and mouse IKK-gamma.BIND12133833 
NEMO interacts with CIKS. This interaction was modeled on a demonstrated interaction between mouse NEMO and human CIKS.BIND12133833 
-HPRD,BioGRID10962024 |10962033 
MAP3K7TAK1 | TGF1amitogen-activated protein kinase kinase kinase 7-HPRD12089335 
MDFII-MF | I-mfaMyoD family inhibitorTwo-hybridBioGRID16189514 
TRAF2MGC:45012 | TRAP | TRAP3TNF receptor-associated factor 2Two-hybridBioGRID16189514 
TRAF3CAP-1 | CD40bp | CRAF1 | LAP1TNF receptor-associated factor 3-HPRD,BioGRID12089335 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
SCHEIDEREIT_IKK_INTERACTING_PROTEINS 5845All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 261153All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_DN 11078All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN 11064All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN 4130All SZGR genes in this pathway
ROSS_AML_WITH_AML1_ETO_FUSION 7655All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_DN 10170All SZGR genes in this pathway
TSENG_IRS1_TARGETS_DN 13588All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP 397206All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway


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