Gene Page: CPLX1

Summary
GeneID  10815
Symbol  CPLX1
Synonyms  CPX-I|CPX1
Description  complexin 1
See related  HGNC:2309|MIM:605032|HPRD:09233|
Locus tag  -
Gene type  protein-coding
Map location  4p16.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
WDR350.890.92
COPB20.890.91
AQR0.890.93
C3orf630.880.91
FNDC3A0.880.90
RAD210.880.90
SSR10.880.91
C1orf90.880.92
ZZZ30.880.91
TRIP120.880.90
Top 10 negatively co-expressed genes
FXYD1-0.70-0.74
MT-CO2-0.70-0.78
AF347015.31-0.68-0.76
AF347015.21-0.68-0.76
AF347015.33-0.67-0.74
IFI27-0.67-0.73
AF347015.8-0.66-0.76
AF347015.27-0.66-0.73
MYL3-0.65-0.71
HIGD1B-0.65-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0019905syntaxin bindingIEASynap (GO term level: 5)-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007268synaptic transmissionTASneuron, Synap, Neurotransmitter (GO term level: 6)7553862 
GO:0006836neurotransmitter transportIEAneuron, Neurotransmitter (GO term level: 5)-
GO:0006887exocytosisTAS7553862 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SNAP25FLJ23079 | RIC-4 | RIC4 | SEC9 | SNAP | SNAP-25 | bA416N4.2 | dJ1068F16.2synaptosomal-associated protein, 25kDaCo-crystal Structure
Reconstituted Complex
BioGRID11832227 |12200427 
STX1AHPC-1 | STX1 | p35-1syntaxin 1A (brain)Affinity Capture-Western
Co-crystal Structure
Reconstituted Complex
BioGRID10449403 |11832227 
|12200427 
-HPRD7553862 
SYT1DKFZp781D2042 | P65 | SVP65 | SYTsynaptotagmin I-HPRD7553862 
VAMP2FLJ11460 | SYB2 | VAMP-2vesicle-associated membrane protein 2 (synaptobrevin 2)-HPRD,BioGRID11832227 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
HOOI_ST7_TARGETS_UP 9457All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_UP 430232All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_UP 10072All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_DN 5443All SZGR genes in this pathway
LEIN_NEURON_MARKERS 6945All SZGR genes in this pathway
MATZUK_SPERMATOZOA 11477All SZGR genes in this pathway
LEE_DOUBLE_POLAR_THYMOCYTE 2717All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1351041111A,m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
miR-1376256321A,m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-5059899951Ahsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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