Gene Page: SUPT16H

Summary
GeneID  11198
Symbol  SUPT16H
Synonyms  CDC68|FACT|FACTP140|FLJ10857|FLJ14010|FLJ34357|SPT16/CDC68
Description  suppressor of Ty 16 homolog (S. cerevisiae)
See related  HGNC:11465|MIM:605012|Ensembl:ENSG00000092201|HPRD:16088|
Locus tag  -
Gene type  protein-coding
Map location  14q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008159positive transcription elongation factor activityTAS10421373 
GO:0008235metalloexopeptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006337nucleosome disassemblyTAS10421373 
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0006508proteolysisIEA-
GO:0006366transcription from RNA polymerase II promoterTAS10421373 
GO:0006281DNA repairIEA-
GO:0006260DNA replicationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005654nucleoplasmEXP12676794 
GO:0005694chromosomeIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BAZ1BWBSCR10 | WBSCR9 | WSTFbromodomain adjacent to zinc finger domain, 1B-HPRD,BioGRID12837248 
H3F3AH3.3A | H3F3 | MGC87782 | MGC87783H3 histone, family 3AH3F3A (Histone 3) interacts with SUPT16H (FACT).BIND15616580 
HES1FLJ20408 | HES-1 | HHL | HRY | bHLHb39hairy and enhancer of split 1, (Drosophila)HES1 promoter interacts with FACT.BIND15546612 
NEK9DKFZp434D0935 | MGC138306 | MGC16714 | NERCC | NERCC1 | Nek8NIMA (never in mitosis gene a)- related kinase 9-HPRD14660563 
SFRS12DKFZp564B176 | MGC133045 | SRrp508 | SRrp86splicing factor, arginine/serine-rich 12-HPRD14559993 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_RNA_POL_II_TRANSCRIPTION 10554All SZGR genes in this pathway
REACTOME_TRANSCRIPTION 210127All SZGR genes in this pathway
REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ 4519All SZGR genes in this pathway
REACTOME_ELONGATION_ARREST_AND_RECOVERY 3214All SZGR genes in this pathway
REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 6132All SZGR genes in this pathway
REACTOME_HIV_INFECTION 207122All SZGR genes in this pathway
REACTOME_HIV_LIFE_CYCLE 12569All SZGR genes in this pathway
REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 10461All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_UP 238144All SZGR genes in this pathway
SENESE_HDAC2_TARGETS_UP 11466All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP 177113All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN 514319All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
FALVELLA_SMOKERS_WITH_LUNG_CANCER 8052All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
KAUFFMANN_DNA_REPAIR_GENES 230137All SZGR genes in this pathway
ZHANG_RESPONSE_TO_CANTHARIDIN_DN 6946All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 11865All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_DN 249165All SZGR genes in this pathway
CHUNG_BLISTER_CYTOTOXICITY_UP 13484All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_UP 13995All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP 2214All SZGR genes in this pathway
CHICAS_RB1_TARGETS_GROWING 243155All SZGR genes in this pathway
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN 157106All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
BILANGES_SERUM_SENSITIVE_GENES 9054All SZGR genes in this pathway
ABRAMSON_INTERACT_WITH_AIRE 4533All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1331421481Ahsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-15/16/195/424/497900906m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-4313463521Ahsa-miR-431UGUCUUGCAGGCCGUCAUGCA
miR-49510991105m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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