Gene Page: CLDN4

Summary
GeneID  1364
Symbol  CLDN4
Synonyms  CPE-R|CPER|CPETR|CPETR1|WBSCR8|hCPE-R
Description  claudin 4
See related  HGNC:2046|MIM:602909|Ensembl:ENSG00000189143|HPRD:04218|
Locus tag  -
Gene type  protein-coding
Map location  7q11.23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABCA80.840.81
PIP5K2A0.840.76
KIF13B0.830.74
ERMN0.830.67
NPC10.830.77
PLD10.820.81
C10orf900.820.71
ANLN0.820.74
ENPP20.820.68
FOLH10.820.67
Top 10 negatively co-expressed genes
C1orf86-0.44-0.57
AC009133.1-0.42-0.45
NOL12-0.42-0.48
SCNM1-0.42-0.52
NR2C2AP-0.42-0.47
FAM128A-0.41-0.49
MED19-0.41-0.47
RPL36-0.41-0.62
CCDC107-0.41-0.49
DALRD3-0.41-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004888transmembrane receptor activityTAS9334247 
GO:0005198structural molecule activityIEA-
GO:0042802identical protein bindingISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009405pathogenesisTAS9334247 
GO:0016338calcium-independent cell-cell adhesionISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005923tight junctionISSBrain (GO term level: 10)-
GO:0005886plasma membraneTAS9334247 |9892664 
GO:0005887integral to plasma membraneTAS9334247 
GO:0030054cell junctionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
TJP1DKFZp686M05161 | MGC133289 | ZO-1tight junction protein 1 (zona occludens 1)-HPRD,BioGRID10601346 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_ADHESION_MOLECULES_CAMS 13493All SZGR genes in this pathway
KEGG_TIGHT_JUNCTION 13486All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 11878All SZGR genes in this pathway
REACTOME_CELL_CELL_COMMUNICATION 12077All SZGR genes in this pathway
REACTOME_CELL_CELL_JUNCTION_ORGANIZATION 5631All SZGR genes in this pathway
REACTOME_TIGHT_JUNCTION_INTERACTIONS 2911All SZGR genes in this pathway
REACTOME_CELL_JUNCTION_ORGANIZATION 7843All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP 450256All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
NAGASHIMA_NRG1_SIGNALING_UP 176123All SZGR genes in this pathway
COLDREN_GEFITINIB_RESISTANCE_DN 230115All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP 271175All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN 6244All SZGR genes in this pathway
MUELLER_METHYLATED_IN_GLIOBLASTOMA 4022All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2 12792All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
AIYAR_COBRA1_TARGETS_DN 2918All SZGR genes in this pathway
MAINA_HYPOXIA_VHL_TARGETS_UP 65All SZGR genes in this pathway
MAINA_VHL_TARGETS_DN 1814All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN 6638All SZGR genes in this pathway
WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN 5529All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
WU_CELL_MIGRATION 184114All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_UP 197110All SZGR genes in this pathway
ZUCCHI_METASTASIS_DN 4429All SZGR genes in this pathway
SWEET_KRAS_TARGETS_UP 8451All SZGR genes in this pathway
HALMOS_CEBPA_TARGETS_DN 4626All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_DN 215132All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_UP 202115All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G2 3018All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
YEGNASUBRAMANIAN_PROSTATE_CANCER 12860All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_DN 5944All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
ELLWOOD_MYC_TARGETS_DN 4027All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K27ME3 269159All SZGR genes in this pathway
COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP 10968All SZGR genes in this pathway
YAMASHITA_LIVER_CANCER_STEM_CELL_UP 4738All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G24 2819All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_DN 222147All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
DELPUECH_FOXO3_TARGETS_UP 6849All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
KOHOUTEK_CCNT1_TARGETS 5026All SZGR genes in this pathway
MALIK_REPRESSED_BY_ESTROGEN 1210All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_DN 428246All SZGR genes in this pathway
ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF 222159All SZGR genes in this pathway


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