Gene Page: MAPK14

Summary
GeneID  1432
Symbol  MAPK14
Synonyms  CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA
Description  mitogen-activated protein kinase 14
See related  HGNC:6876|MIM:600289|Ensembl:ENSG00000112062|HPRD:02619|
Locus tag  RP1-179N16.5
Gene type  protein-coding
Map location  6p21.3-p21.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0305 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004707MAP kinase activityIEA-
GO:0004708MAP kinase kinase activityTAS10706854 
GO:0008339MP kinase activityIDA7997261 
GO:0005515protein bindingIPI9792677 |12761180 |16189514 
|16636664 |16751104 
|17255097 
GO:0005524ATP bindingIEA-
GO:0004674protein serine/threonine kinase activityEXP8846784 |9687510 
GO:0004674protein serine/threonine kinase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationIEA-
GO:0007265Ras protein signal transductionEXP11520933 
GO:0007243protein kinase cascadeIDA10838079 
GO:0006950response to stressIDA7997261 
GO:0007166cell surface receptor linked signal transductionTAS10706854 
GO:0006935chemotaxisTAS10706854 
GO:0006928cell motionTAS10912793 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP9687510 
GO:0005634nucleusISS-
GO:0005654nucleoplasmEXP8846784 
GO:0005737cytoplasmISS-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AKT1AKT | MGC99656 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHAv-akt murine thymoma viral oncogene homolog 1Affinity Capture-Western
Biochemical Activity		BioGRID11042204 
ATF2CRE-BP1 | CREB2 | HB16 | MGC111558 | TREB7activating transcription factor 2An unspecified isoform of p38 interacts with and phosphorylates ATF2.BIND9155018 
An unspecified isoform of p38 interacts with and phosphorylates ATF2.BIND9235954 
p38 phosphorylates ATF2. This interaction was modelled on a demonstrated interaction between human p38 and ATF2 from an unspecified species.BIND15692053 
-HPRD,BioGRID7535770 
CDC25ACDC25A2cell division cycle 25 homolog A (S. pombe)Reconstituted ComplexBioGRID12963847 
CDC25B-cell division cycle 25 homolog B (S. pombe)Biochemical Activity
Reconstituted Complex		BioGRID11333986 
p38-alpha interacts with and phosphorylates CDC25B.BIND15629715 
CDC25CCDC25cell division cycle 25 homolog C (S. pombe)-HPRD,BioGRID11333986 
CREB1CREB | MGC9284cAMP responsive element binding protein 1-HPRD,BioGRID11377386 
CSNK2A1CK2A1 | CKIIcasein kinase 2, alpha 1 polypeptideAffinity Capture-Western
Reconstituted Complex		BioGRID10747897 
CSNK2A2CK2A2 | CSNK2A1 | FLJ43934casein kinase 2, alpha prime polypeptide-HPRD10747897 
CSNK2BCK2B | CK2N | CSK2B | G5A | MGC138222 | MGC138224casein kinase 2, beta polypeptide-HPRD10747897 
DDIT3CEBPZ | CHOP | CHOP10 | GADD153 | MGC4154DNA-damage-inducible transcript 3-HPRD,BioGRID8650547 
DUSP1CL100 | HVH1 | MKP-1 | MKP1 | PTPN10dual specificity phosphatase 1-HPRD7535770 
Affinity Capture-Western
Two-hybrid		BioGRID11278799 |11359773 
DUSP10MKP-5 | MKP5dual specificity phosphatase 10Affinity Capture-Western
Biochemical Activity
Reconstituted Complex
Two-hybrid		BioGRID10391943 |11157753 
|11359773 
An unspecified isoform of MAPK14 interacts with DUSP10.BIND10391943 
-HPRD10391943 |10597297 
|11359773 
DUSP16KIAA1700 | MGC129701 | MGC129702 | MKP-7 | MKP7dual specificity phosphatase 16-HPRD,BioGRID11359773 |11489891 
|14586399 
DUSP2PAC-1 | PAC1dual specificity phosphatase 2-HPRD7535770 
DUSP22JKAP | JSP1 | MKPX | VHXdual specificity phosphatase 22-HPRD11346645 
DUSP4HVH2 | MKP-2 | MKP2 | TYPdual specificity phosphatase 4-HPRD,BioGRID11387337 
DUSP6MKP3 | PYST1dual specificity phosphatase 6Affinity Capture-WesternBioGRID11359773 
DYRK1BMIRKdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B-HPRD,BioGRID10910078 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Biochemical ActivityBioGRID7535770 
ELK1-ELK1, member of ETS oncogene familyElk-1 is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Elk-1 and p38 MAPK from an unspecified species.BIND9130707 
-HPRD8622669 
An unspecified isoform of p38 interacts with and phosphorylates Elk-1.BIND9155018 
ELK4SAP1ELK4, ETS-domain protein (SRF accessory protein 1)An unspecified isoform of p38 interacts with and phosphorylates Sap-1a.BIND9235954 
Sap-1a is phosphorylated by an unspecified isoform of p38 MAPK. This interaction was modeled on a demonstrated interaction between human Sap-1a and p38 MAPK from an unspecified species.BIND9130707 
ETV1DKFZp781L0674 | ER81 | MGC104699 | MGC120533 | MGC120534ets variant 1Biochemical ActivityBioGRID11551945 
FLNAABP-280 | ABPX | DKFZp434P031 | FLN | FLN1 | FMD | MNS | NHBP | OPD | OPD1 | OPD2filamin A, alpha (actin binding protein 280)-HPRD11390380 
FUBP1FBP | FUBPfar upstream element (FUSE) binding protein 1Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID12819782 
GMFBGMFglia maturation factor, beta-HPRD,BioGRID8798479 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2-HPRD8695800 
HTRA2OMI | PARK13 | PRSS25HtrA serine peptidase 2-HPRD,BioGRID10644717 
JUNAP-1 | AP1 | c-Junjun oncogeneAn unspecified isoform of p38 interacts with and phosphorylates c-Jun.BIND9155018 
KARSKARS2 | KIAA0070 | KRSlysyl-tRNA synthetaseTwo-hybridBioGRID12819782 
KRT18CYK18 | K18keratin 18-HPRD,BioGRID11788583 
MAP2K1MAPKK1 | MEK1 | MKK1 | PRKMK1mitogen-activated protein kinase kinase 1-HPRD12697810 
MAP2K3MAPKK3 | MEK3 | MKK3 | PRKMK3mitogen-activated protein kinase kinase 3-HPRD7839144|8622669 
Biochemical ActivityBioGRID11279118 
MKK3 phosphorylates an unspecified isoform of p38. This interaction was modeled on a demonstrated interaction between human MKK3 and p38 from an unspecified species.BIND8622669 
MAP2K4JNKK | JNKK1 | MAPKK4 | MEK4 | MKK4 | PRKMK4 | SEK1 | SERK1mitogen-activated protein kinase kinase 4-HPRD,BioGRID7716521 
MAP2K6MAPKK6 | MEK6 | MKK6 | PRKMK6 | SAPKK3mitogen-activated protein kinase kinase 6-HPRD,BioGRID8626699 
MAP2K7Jnkk2 | MAPKK7 | MKK7 | PRKMK7mitogen-activated protein kinase kinase 7Biochemical ActivityBioGRID9207092 
MAP3K7IP13'-Tab1 | MGC57664 | TAB1mitogen-activated protein kinase kinase kinase 7 interacting protein 1TAB1 interacts with an unspecified isoform of p38.BIND12829618 
-HPRD,BioGRID11847341 
MAPK1ERK | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapkmitogen-activated protein kinase 1-HPRD,BioGRID12697810 
MAPK14CSBP1 | CSBP2 | CSPB1 | EXIP | Mxi2 | PRKM14 | PRKM15 | RK | SAPK2A | p38 | p38ALPHAmitogen-activated protein kinase 14Biochemical Activity
Two-hybrid		BioGRID11847341 |12819782 
MAPK3ERK1 | HS44KDAP | HUMKER1A | MGC20180 | P44ERK1 | P44MAPK | PRKM3mitogen-activated protein kinase 3-HPRD,BioGRID12697810 
MAPKAPK2MK2mitogen-activated protein kinase-activated protein kinase 2-HPRD,BioGRID9768359 |11042204 
|11551945 
MAPKAPK33PK | MAPKAP3mitogen-activated protein kinase-activated protein kinase 3-HPRD,BioGRID11157753 
MARSFLJ35667 | METRS | MTRNSmethionyl-tRNA synthetase-HPRD9878398 
MEF2AADCAD1 | RSRFC4 | RSRFC9myocyte enhancer factor 2A-HPRD,BioGRID10330143 
MEF2C-myocyte enhancer factor 2C-HPRD9753748 |10330143 
MKNK1MNK1MAP kinase interacting serine/threonine kinase 1-HPRD9155018 
Affinity Capture-WesternBioGRID11157753 
An unspecified isoform of p38 interacts with and phosphorylates MNK1.BIND9155018 
MKNK2GPRK7 | MNK2MAP kinase interacting serine/threonine kinase 2-HPRD12897141 
NCF1CSH3PXD1Cneutrophil cytosolic factor 1C pseudogenep38-alpha interacts with and phosphorylates p47phox.BIND15629715 
PLCB2FLJ38135phospholipase C, beta 2Affinity Capture-WesternBioGRID12054652 
PMLMYL | PP8675 | RNF71 | TRIM19promyelocytic leukemia-HPRD15273249 
PTPN7BPTP-4 | HEPTP | LC-PTP | LPTP | PTPNIprotein tyrosine phosphatase, non-receptor type 7-HPRD10559944 
RPS6KA3CLS | HU-3 | ISPK-1 | MAPKAPK1B | MRX19 | RSK | RSK2 | S6K-alpha3 | p90-RSK2 | pp90RSK2ribosomal protein S6 kinase, 90kDa, polypeptide 3Affinity Capture-WesternBioGRID11157753 
RPS6KA4MSK2 | RSK-Bribosomal protein S6 kinase, 90kDa, polypeptide 4-HPRD,BioGRID9792677 
RPS6KA5MGC1911 | MSK1 | MSPK1 | RLPKribosomal protein S6 kinase, 90kDa, polypeptide 5Affinity Capture-WesternBioGRID11157753 
SCYE1AIMP1 | EMAP-2 | EMAP-II | EMAP2 | EMAPII | p43small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)-HPRD9878398 
SLC12A2BSC | BSC2 | MGC104233 | NKCC1solute carrier family 12 (sodium/potassium/chloride transporters), member 2Affinity Capture-WesternBioGRID14563843 
SLC44A1CD92 | CDW92 | CHTL1 | CTL1 | RP11-287A8.1solute carrier family 44, member 1-HPRD9707433 
SMAD7CRCS3 | FLJ16482 | MADH7 | MADH8SMAD family member 7-HPRD,BioGRID12589052 
SPAG9FLJ13450 | FLJ14006 | FLJ26141 | FLJ34602 | HLC4 | JLP | KIAA0516 | MGC117291 | MGC14967 | MGC74461 | PHET | PIG6sperm associated antigen 9-HPRD,BioGRID12391307 
STK39DCHT | DKFZp686K05124 | PASK | SPAKserine threonine kinase 39 (STE20/SPS1 homolog, yeast)-HPRD10980603 
Affinity Capture-WesternBioGRID14563843 
ZFP36L1BRF1 | Berg36 | ERF-1 | ERF1 | RNF162B | TIS11B | cMG1zinc finger protein 36, C3H type-like 1Affinity Capture-Western
Two-hybrid		BioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
KEGG_VEGF_SIGNALING_PATHWAY 7653All SZGR genes in this pathway
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY 10288All SZGR genes in this pathway
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY 6247All SZGR genes in this pathway
KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY 7151All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 10889All SZGR genes in this pathway
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 7958All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 11878All SZGR genes in this pathway
KEGG_NEUROTROPHIN_SIGNALING_PATHWAY 126103All SZGR genes in this pathway
KEGG_GNRH_SIGNALING_PATHWAY 10177All SZGR genes in this pathway
KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION 8659All SZGR genes in this pathway
KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS 5343All SZGR genes in this pathway
KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION 6844All SZGR genes in this pathway
KEGG_LEISHMANIA_INFECTION 7256All SZGR genes in this pathway
BIOCARTA_BCR_PATHWAY 3728All SZGR genes in this pathway
BIOCARTA_BIOPEPTIDES_PATHWAY 4535All SZGR genes in this pathway
BIOCARTA_HDAC_PATHWAY 3225All SZGR genes in this pathway
BIOCARTA_FMLP_PATHWAY 3929All SZGR genes in this pathway
BIOCARTA_GATA3_PATHWAY 1615All SZGR genes in this pathway
BIOCARTA_HCMV_PATHWAY 1716All SZGR genes in this pathway
BIOCARTA_IL12_PATHWAY 2317All SZGR genes in this pathway
BIOCARTA_KERATINOCYTE_PATHWAY 4638All SZGR genes in this pathway
BIOCARTA_PYK2_PATHWAY 3124All SZGR genes in this pathway
BIOCARTA_EGFR_SMRTE_PATHWAY 1111All SZGR genes in this pathway
BIOCARTA_MAPK_PATHWAY 8768All SZGR genes in this pathway
BIOCARTA_NFAT_PATHWAY 5645All SZGR genes in this pathway
BIOCARTA_NTHI_PATHWAY 2420All SZGR genes in this pathway
BIOCARTA_ARENRF2_PATHWAY 139All SZGR genes in this pathway
BIOCARTA_P38MAPK_PATHWAY 4031All SZGR genes in this pathway
BIOCARTA_CCR5_PATHWAY 2016All SZGR genes in this pathway
BIOCARTA_RB_PATHWAY 1311All SZGR genes in this pathway
BIOCARTA_EIF4_PATHWAY 2419All SZGR genes in this pathway
BIOCARTA_IL1R_PATHWAY 3329All SZGR genes in this pathway
BIOCARTA_TALL1_PATHWAY 1515All SZGR genes in this pathway
BIOCARTA_41BB_PATHWAY 1715All SZGR genes in this pathway
BIOCARTA_SARS_PATHWAY 105All SZGR genes in this pathway
BIOCARTA_STRESS_PATHWAY 2518All SZGR genes in this pathway
BIOCARTA_TOLL_PATHWAY 3731All SZGR genes in this pathway
BIOCARTA_CREB_PATHWAY 2725All SZGR genes in this pathway
SIG_CD40PATHWAYMAP 3428All SZGR genes in this pathway
ST_P38_MAPK_PATHWAY 3728All SZGR genes in this pathway
ST_ADRENERGIC 3629All SZGR genes in this pathway
PID_ENDOTHELIN_PATHWAY 6352All SZGR genes in this pathway
PID_BCR_5PATHWAY 6550All SZGR genes in this pathway
PID_P73PATHWAY 7959All SZGR genes in this pathway
PID_P38_MKK3_6PATHWAY 2621All SZGR genes in this pathway
PID_NFKAPPAB_ATYPICAL_PATHWAY 1715All SZGR genes in this pathway
PID_IL4_2PATHWAY 6543All SZGR genes in this pathway
PID_CD40_PATHWAY 3126All SZGR genes in this pathway
PID_IL12_2PATHWAY 6354All SZGR genes in this pathway
PID_P38_ALPHA_BETA_PATHWAY 3125All SZGR genes in this pathway
PID_CDC42_PATHWAY 7051All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 5041All SZGR genes in this pathway
PID_FAS_PATHWAY 3829All SZGR genes in this pathway
PID_TXA2PATHWAY 5743All SZGR genes in this pathway
PID_NFAT_3PATHWAY 5447All SZGR genes in this pathway
PID_REG_GR_PATHWAY 8260All SZGR genes in this pathway
PID_IL2_1PATHWAY 5543All SZGR genes in this pathway
PID_AR_TF_PATHWAY 5338All SZGR genes in this pathway
PID_ATF2_PATHWAY 5943All SZGR genes in this pathway
PID_IL6_7_PATHWAY 4740All SZGR genes in this pathway
PID_P38_MK2_PATHWAY 2119All SZGR genes in this pathway
PID_RETINOIC_ACID_PATHWAY 3023All SZGR genes in this pathway
PID_CXCR3_PATHWAY 4334All SZGR genes in this pathway
PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY 3829All SZGR genes in this pathway
PID_EPO_PATHWAY 3429All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY 6957All SZGR genes in this pathway
PID_P53_REGULATION_PATHWAY 5950All SZGR genes in this pathway
PID_S1P_S1P2_PATHWAY 2419All SZGR genes in this pathway
PID_MAPK_TRK_PATHWAY 3431All SZGR genes in this pathway
PID_LYMPH_ANGIOGENESIS_PATHWAY 2516All SZGR genes in this pathway
PID_RAC1_PATHWAY 5437All SZGR genes in this pathway
PID_RB_1PATHWAY 6546All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_TRIF_MEDIATED_TLR3_SIGNALING 7454All SZGR genes in this pathway
REACTOME_CELL_CELL_COMMUNICATION 12077All SZGR genes in this pathway
REACTOME_SIGNALLING_TO_RAS 2723All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 137105All SZGR genes in this pathway
REACTOME_SIGNALLING_TO_ERKS 3630All SZGR genes in this pathway
REACTOME_P38MAPK_EVENTS 1312All SZGR genes in this pathway
REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION 2420All SZGR genes in this pathway
REACTOME_ERK_MAPK_TARGETS 2117All SZGR genes in this pathway
REACTOME_ADP_SIGNALLING_THROUGH_P2RY1 2516All SZGR genes in this pathway
REACTOME_SIGNAL_AMPLIFICATION 3119All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA 284128All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA 330155All SZGR genes in this pathway
REACTOME_MYOGENESIS 2820All SZGR genes in this pathway
REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE 5037All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS 108All SZGR genes in this pathway
REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES 3024All SZGR genes in this pathway
REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION 1812All SZGR genes in this pathway
REACTOME_PLATELET_HOMEOSTASIS 7849All SZGR genes in this pathway
REACTOME_PLATELET_SENSITIZATION_BY_LDL 169All SZGR genes in this pathway
REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 8450All SZGR genes in this pathway
REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 7757All SZGR genes in this pathway
REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP 179All SZGR genes in this pathway
REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE 7253All SZGR genes in this pathway
REACTOME_DSCAM_INTERACTIONS 1110All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 8363All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_ACTIVATED_TLR4_SIGNALLING 9369All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_TOLL_RECEPTOR_CASCADES 11884All SZGR genes in this pathway
REACTOME_NOD1_2_SIGNALING_PATHWAY 3022All SZGR genes in this pathway
REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS 4633All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
LIU_SOX4_TARGETS_DN 309191All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN 384220All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP 6446All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN 6439All SZGR genes in this pathway
KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN 7550All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_DN 13797All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP 169127All SZGR genes in this pathway
GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION 2216All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
WANG_RESPONSE_TO_BEXAROTENE_DN 2919All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_UP 209139All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_ONLY_DN 4430All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
RANKIN_ANGIOGENIC_TARGETS_OF_VHL_HIF2A_UP 55All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 206136All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN 4130All SZGR genes in this pathway
UEDA_PERIFERAL_CLOCK 169111All SZGR genes in this pathway
TENEDINI_MEGAKARYOCYTE_MARKERS 6648All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 5135All SZGR genes in this pathway
PARK_HSC_AND_MULTIPOTENT_PROGENITORS 5033All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
HOEGERKORP_CD44_TARGETS_DIRECT_UP 2721All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_6HR_UP 3731All SZGR genes in this pathway
KAYO_AGING_MUSCLE_DN 12376All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
ZHU_CMV_8_HR_DN 5340All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D8 4029All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 271175All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
SASSON_RESPONSE_TO_GONADOTROPHINS_DN 8766All SZGR genes in this pathway
SASSON_RESPONSE_TO_FORSKOLIN_UP 9058All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP 242159All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.16056121A,m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5066046111A,m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-125/35116101616m8hsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-12832391A,m8hsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-142-5p158915961A,m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-18562681Ahsa-miR-185brainUGGAGAGAAAGGCAGUUC
miR-19205720641A,m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-2214511457m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-224213219m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-273339m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-505110511121A,m8hsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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