Gene Page: DAB1

Summary
GeneID  1600
Symbol  DAB1
Synonyms  -
Description  disabled homolog 1 (Drosophila)
See related  HGNC:2661|MIM:603448|Ensembl:ENSG00000173406|HPRD:04582|
Locus tag  RP6-239D12.2
Gene type  protein-coding
Map location  1p32-p31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02692 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 7.813 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZNF8620.900.91
POLS0.890.93
INTS30.890.92
DHX160.890.92
JARID20.880.90
KDM2A0.880.93
DIAPH10.880.93
ZMYM30.880.94
MEN10.880.92
MBTPS10.880.93
Top 10 negatively co-expressed genes
AF347015.31-0.75-0.84
MT-CO2-0.73-0.83
AF347015.27-0.71-0.79
AF347015.33-0.71-0.78
AF347015.8-0.70-0.81
MT-CYB-0.70-0.78
FXYD1-0.69-0.77
HIGD1B-0.69-0.82
AF347015.21-0.69-0.87
S100B-0.68-0.75
Gene Ontology
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentIEAneurite (GO term level: 5)-
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APLP1APLPamyloid beta (A4) precursor-like protein 1-HPRD,BioGRID10460257 
APLP2APPH | APPL2 | CDEBPamyloid beta (A4) precursor-like protein 2-HPRD,BioGRID10460257 
APPAAA | ABETA | ABPP | AD1 | APPI | CTFgamma | CVAP | PN2amyloid beta (A4) precursor protein-HPRD,BioGRID10460257 
-HPRD9837937 |10460257 
CRKCRKIIv-crk sarcoma virus CT10 oncogene homolog (avian)-HPRD15062102 
DAB2IPAF9Q34 | AIP1 | DIP1/2 | FLJ39072 | KIAA1743DAB2 interacting protein-HPRD11812785 
LDLRFH | FHClow density lipoprotein receptorReconstituted Complex
Two-hybrid		BioGRID9837937 |10827173 
-HPRD10380922 
LRP1A2MR | APOER | APR | CD91 | FLJ16451 | IGFBP3R | LRP | MGC88725 | TGFBR5low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)-HPRD,BioGRID10827173 
LRP2DBS | gp330low density lipoprotein-related protein 2-HPRD,BioGRID10827173 
LRP8APOER2 | HSZ75190 | MCI1low density lipoprotein receptor-related protein 8, apolipoprotein e receptor-HPRD10380922 
Two-hybridBioGRID10827173 
MYO6DFNA22 | DFNB37 | KIAA0389myosin VIReconstituted ComplexBioGRID11967127 
PAFAH1B1LIS1 | LIS2 | MDCR | MDS | PAFAHplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa-HPRD14578885 
PCDH18DKFZp434B0923 | KIAA1562 | PCDH68Lprotocadherin 18-HPRD11716507 
PLCG1PLC-II | PLC1 | PLC148 | PLCgamma1phospholipase C, gamma 1-HPRD15062102 
RELNPRO1598 | RLreelin-HPRD11137154 
SIAH1FLJ08065 | HUMSIAH | Siah-1 | Siah-1a | hSIAH1seven in absentia homolog 1 (Drosophila)-HPRD,BioGRID12646221 
VLDLRCHRMQ1 | FLJ35024 | VLDLRCHvery low density lipoprotein receptor-HPRD10380922 
Two-hybridBioGRID10827173 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_REELIN_PATHWAY 2929All SZGR genes in this pathway
PID_LIS1_PATHWAY 2822All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_DN 12073All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 7037All SZGR genes in this pathway
LEE_LIVER_CANCER_CIPROFIBRATE_UP 6042All SZGR genes in this pathway
SANSOM_APC_TARGETS_DN 366238All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_UP 8550All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
OUYANG_PROSTATE_CANCER_PROGRESSION_DN 2116All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP 430288All SZGR genes in this pathway
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN 157106All SZGR genes in this pathway


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