Gene Page: DVL1

Summary
GeneID  1855
Symbol  DVL1
Synonyms  DVL|MGC54245
Description  dishevelled, dsh homolog 1 (Drosophila)
See related  HGNC:3084|MIM:601365|Ensembl:ENSG00000107404|HPRD:03220|
Locus tag  -
Gene type  protein-coding
Map location  1p36
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIEA-
GO:0003674molecular_functionND-
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI14750955 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016055Wnt receptor signaling pathwayIEA-
GO:0007242intracellular signaling cascadeIEA-
GO:0009653anatomical structure morphogenesisTAS8817329 
GO:0007507heart developmentTAS8817329 
GO:0007275multicellular organismal developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005737cytoplasmNAS-
GO:0005737cytoplasmTAS9192851 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARRB1ARB1 | ARR1arrestin, beta 1-HPRD,BioGRID11742073 
ATN1B37 | D12S755E | DRPLA | NODatrophin 1Two-hybridBioGRID10332026 
AXIN1AXIN | MGC52315axin 1Affinity Capture-WesternBioGRID10428961 
-HPRD9482734 |10330403 
BRD7BP75 | CELTIX1 | NAG4bromodomain containing 7-HPRD12941796 
CSNK1DHCKIDcasein kinase 1, delta-HPRD,BioGRID11818547 
CSNK1EHCKIE | MGC10398casein kinase 1, epsilon-HPRD,BioGRID11487578 |11818547 
CSNK2A1CK2A1 | CKIIcasein kinase 2, alpha 1 polypeptide-HPRD,BioGRID10806215 
CTNNB1CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923catenin (cadherin-associated protein), beta 1, 88kDa-HPRD,BioGRID10806215 
CXXC4IDAX | MGC149872CXXC finger 4-HPRD11113207 
DAAM1FLJ41657 | KIAA0666dishevelled associated activator of morphogenesis 1-HPRD11779461 
DAB2DOC-2 | DOC2 | FLJ26626disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)Reconstituted ComplexBioGRID12805222 
DIXDC1CCD1 | KIAA1735DIX domain containing 1-HPRD15262978 
DVL1DVL | MGC54245dishevelled, dsh homolog 1 (Drosophila)-HPRD,BioGRID10330181 
DVL3KIAA0208dishevelled, dsh homolog 3 (Drosophila)-HPRD,BioGRID10330181 
EPS8-epidermal growth factor receptor pathway substrate 8-HPRD,BioGRID10581192 
FRAT1FLJ97193frequently rearranged in advanced T-cell lymphomas-HPRD,BioGRID10428961 
GSK3B-glycogen synthase kinase 3 beta-HPRD10428961 
HECW1KIAA0322 | NEDL1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1-HPRD,BioGRID14684739 
SMAD1BSP1 | JV4-1 | JV41 | MADH1 | MADR1SMAD family member 1Reconstituted ComplexBioGRID12650946 
SMAD2JV18 | JV18-1 | MADH2 | MADR2 | MGC22139 | MGC34440 | hMAD-2 | hSMAD2SMAD family member 2-HPRD,BioGRID12650946 
SMAD3DKFZp586N0721 | DKFZp686J10186 | HSPC193 | HsT17436 | JV15-2 | MADH3 | MGC60396SMAD family member 3Reconstituted Complex
Two-hybrid
BioGRID12650946 
SMAD4DPC4 | JIP | MADH4SMAD family member 4Reconstituted ComplexBioGRID12650946 
SMAD7CRCS3 | FLJ16482 | MADH7 | MADH8SMAD family member 7Reconstituted ComplexBioGRID12650946 
USP13ISOT3 | IsoT-3ubiquitin specific peptidase 13 (isopeptidase T-3)Two-hybridBioGRID16169070 
VANGL1LPP2 | MGC5338 | STB2 | STBM2vang-like 1 (van gogh, Drosophila)-HPRD15456783 
VANGL2KIAA1215 | LPP1 | LTAP | MGC119403 | MGC119404 | STB1 | STBM | STBM1vang-like 2 (van gogh, Drosophila)-HPRD12490194 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_WNT_SIGNALING_PATHWAY 151112All SZGR genes in this pathway
KEGG_NOTCH_SIGNALING_PATHWAY 4735All SZGR genes in this pathway
KEGG_MELANOGENESIS 10280All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_BASAL_CELL_CARCINOMA 5544All SZGR genes in this pathway
BIOCARTA_AGR_PATHWAY 3631All SZGR genes in this pathway
BIOCARTA_ALK_PATHWAY 3729All SZGR genes in this pathway
BIOCARTA_GSK3_PATHWAY 2726All SZGR genes in this pathway
BIOCARTA_PITX2_PATHWAY 1515All SZGR genes in this pathway
BIOCARTA_PS1_PATHWAY 1414All SZGR genes in this pathway
BIOCARTA_WNT_PATHWAY 2624All SZGR genes in this pathway
WNT_SIGNALING 8971All SZGR genes in this pathway
ST_WNT_BETA_CATENIN_PATHWAY 3428All SZGR genes in this pathway
PID_WNT_NONCANONICAL_PATHWAY 3226All SZGR genes in this pathway
PID_BETA_CATENIN_DEG_PATHWAY 1817All SZGR genes in this pathway
PID_PS1_PATHWAY 4639All SZGR genes in this pathway
PID_WNT_CANONICAL_PATHWAY 2018All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP 176115All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_7 2722All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH3_21_UP 4430All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
VERRECCHIA_RESPONSE_TO_TGFB1_C2 2518All SZGR genes in this pathway
VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 5843All SZGR genes in this pathway
MURAKAMI_UV_RESPONSE_24HR 2013All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN 13892All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway


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