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|
| GeneID |
2055
|
| Symbol |
CLN8
|
| Synonyms |
C8orf61|EPMR|FLJ39417
|
| Description |
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| See related |
HGNC:2079|MIM:607837|Ensembl:ENSG00000182372|HPRD:06383| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
8p23 |
|
| |
|
|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 3 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| CIT | 0.80 | 0.76 | | |
| C3orf57 | 0.79 | 0.66 | | |
| SGPP2 | 0.79 | 0.72 | | |
| INPP4B | 0.78 | 0.74 | | |
| EMB | 0.77 | 0.66 | | |
| WNT2 | 0.77 | 0.62 | | |
| KCNC2 | 0.77 | 0.65 | | |
| MCF2 | 0.77 | 0.61 | | |
| PHACTR2 | 0.76 | 0.63 | | |
| BTBD11 | 0.76 | 0.75 | | |
Top 10 negatively co-expressed genes | | WDR86 | -0.39 | -0.46 | | |
| PLEKHO1 | -0.39 | -0.46 | | |
| NR2C2AP | -0.37 | -0.44 | | |
| RPL18 | -0.36 | -0.61 | | |
| EMID1 | -0.36 | -0.45 | | |
| RPL12 | -0.36 | -0.53 | | |
| RPS19P3 | -0.36 | -0.61 | | |
| RPL14 | -0.36 | -0.47 | | |
| TRAF4 | -0.36 | -0.54 | | |
| RPLP1 | -0.36 | -0.53 | | |
|
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0051935 | glutamate uptake during transmission of nerve impulse | IEA | neuron, glutamate, Neurotransmitter, Glial (GO term level: 11) | - |
| GO:0021522 | spinal cord motor neuron differentiation | IEA | neuron, Brain (GO term level: 9) | - |
| GO:0007399 | nervous system development | IMP | neurite (GO term level: 5) | 10508524 |
| GO:0001306 | age-dependent response to oxidative stress | IEA | | - |
| GO:0007006 | mitochondrial membrane organization | IEA | | - |
| GO:0008203 | cholesterol metabolic process | IMP | | 16086686 |
| GO:0008306 | associative learning | IEA | | - |
| GO:0008610 | lipid biosynthetic process | NAS | | 12151215 |
| GO:0008361 | regulation of cell size | IEA | | - |
| GO:0007628 | adult walking behavior | IEA | | - |
| GO:0007040 | lysosome organization | IEA | | - |
| GO:0006644 | phospholipid metabolic process | IMP | | 16086686 |
| GO:0006869 | lipid transport | NAS | | 12151215 |
| GO:0043066 | negative regulation of apoptosis | IEA | | - |
| GO:0050885 | neuromuscular process controlling balance | IEA | | - |
| GO:0050881 | musculoskeletal movement | IEA | | - |
| GO:0051348 | negative regulation of transferase activity | IEA | | - |
| GO:0035176 | social behavior | IEA | | - |
| GO:0045861 | negative regulation of proteolysis | NAS | | 12151215 |
| GO:0050884 | neuromuscular process controlling posture | IEA | | - |
| GO:0044257 | cellular protein catabolic process | IEA | | - |
| GO:0046513 | ceramide biosynthetic process | NAS | | 12151215 |
| GO:0045494 | photoreceptor cell maintenance | IEA | | - |
| GO:0060041 | retina development in camera-type eye | IEA | | - |
| GO:0060052 | neurofilament cytoskeleton organization | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005789 | endoplasmic reticulum membrane | IEA | | - |
| GO:0005783 | endoplasmic reticulum | IDA | | 10861296 |
| GO:0016020 | membrane | IEA | | - |
| GO:0016021 | integral to membrane | NAS | | 10508524 |10861296 |
| GO:0033116 | ER-Golgi intermediate compartment membrane | IEA | | - |
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