Gene Page: ALDOA

Summary
GeneID  226
Symbol  ALDOA
Synonyms  ALDA|MGC10942|MGC17716|MGC17767
Description  aldolase A, fructose-bisphosphate
See related  HGNC:414|MIM:103850|Ensembl:ENSG00000149925|HPRD:00070|
Locus tag  -
Gene type  protein-coding
Map location  16p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CPEB10.510.56
AKTIP0.500.51
MRAP20.500.51
TPD520.500.57
OGDHL0.500.56
ABHD120.500.52
AL121758.10.490.55
AL049829.10.490.54
TOM10.490.51
TTC7B0.490.50
Top 10 negatively co-expressed genes
RPL18-0.35-0.41
RPS19P3-0.34-0.39
GLTSCR2-0.34-0.27
RPS3P3-0.34-0.34
RPS16P1-0.33-0.40
RPL28-0.33-0.40
EIF4EBP1-0.33-0.37
RPS8-0.33-0.33
IGFBP2-0.32-0.28
RPL10-0.32-0.27
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15231747 
GO:0004332fructose-bisphosphate aldolase activityTAS2825199 
GO:0016829lyase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006096glycolysisTAS2825199 
GO:0006000fructose metabolic processTAS2825199 
GO:0008152metabolic processIEA-
GO:0006941striated muscle contractionTAS8598869 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATP6V1E1ATP6E | ATP6E2 | ATP6V1E | P31 | Vma4ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1-HPRD,BioGRID11399750 
DYNLL1DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1dynein, light chain, LC8-type 1-HPRD14760703 
FANCAFA | FA-H | FA1 | FAA | FACA | FAH | FANCH | MGC75158Fanconi anemia, complementation group ATwo-hybridBioGRID14499622 
GPD2GDH2 | GPDM | mGPDHglycerol-3-phosphate dehydrogenase 2 (mitochondrial)-HPRD2065091 |6406231 
PLD2-phospholipase D2-HPRD,BioGRID11876650 
TUBB2ATUBB | TUBB2 | dJ40E16.7tubulin, beta 2A-HPRD8103323 
XRN1DKFZp434P0721 | DKFZp686B22225 | DKFZp686F19113 | FLJ41903 | SEP15'-3' exoribonuclease 1-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLYCOLYSIS_GLUCONEOGENESIS 6241All SZGR genes in this pathway
KEGG_PENTOSE_PHOSPHATE_PATHWAY 2714All SZGR genes in this pathway
KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 3423All SZGR genes in this pathway
BIOCARTA_MTA3_PATHWAY 1910All SZGR genes in this pathway
PID_HIF1_TFPATHWAY 6652All SZGR genes in this pathway
REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ 8956All SZGR genes in this pathway
REACTOME_GLYCOLYSIS 2918All SZGR genes in this pathway
REACTOME_GLUCONEOGENESIS 3421All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_GLUCOSE_METABOLISM 6942All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
WINTER_HYPOXIA_UP 9257All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_DN 7746All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN 2316All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_6 8454All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP 176111All SZGR genes in this pathway
BALLIF_DEVELOPMENTAL_DISABILITY_P16_P12_DELETION 138All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
PENG_LEUCINE_DEPRIVATION_DN 187122All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_UP 6238All SZGR genes in this pathway
SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP 4530All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
NADLER_OBESITY_DN 4834All SZGR genes in this pathway
CROMER_METASTASIS_DN 8158All SZGR genes in this pathway
KIM_HYPOXIA 2521All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_METHOTREXATE_DN 2719All SZGR genes in this pathway
MODY_HIPPOCAMPUS_POSTNATAL 6350All SZGR genes in this pathway
HARRIS_HYPOXIA 8164All SZGR genes in this pathway
LEONARD_HYPOXIA 4735All SZGR genes in this pathway
BURTON_ADIPOGENESIS_5 12678All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_DN 215132All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR 14984All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN 4631All SZGR genes in this pathway
SEMENZA_HIF1_TARGETS 3632All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE 7750All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM 6647All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST 13293All SZGR genes in this pathway
HILLION_HMGA1_TARGETS 9071All SZGR genes in this pathway
BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_DN 2416All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN 193112All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_UP 10575All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
MOOTHA_GLUCONEOGENESIS 3223All SZGR genes in this pathway
MOOTHA_GLYCOLYSIS 2113All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_UP 307182All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
QI_HYPOXIA 14096All SZGR genes in this pathway
WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 2821All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP 8950All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-12227341A,m8hsa-miR-122aUGGAGUGUGACAAUGGUGUUUGU
miR-34/4491721791A,m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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