Gene Page: ARHGAP26

Summary
GeneID  23092
Symbol  ARHGAP26
Synonyms  FLJ42530|GRAF|KIAA0621|OPHN1L|OPHN1L1
Description  Rho GTPase activating protein 26
See related  HGNC:17073|MIM:605370|Ensembl:ENSG00000145819|HPRD:05643|
Locus tag  -
Gene type  protein-coding
Map location  5q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00459 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01718 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005100Rho GTPase activator activityNAS10908648 
GO:0005096GTPase activator activityIEA-
GO:0005515protein bindingIPI11432776 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentNASneurite (GO term level: 5)9582072 
GO:0007165signal transductionIEA-
GO:0030036actin cytoskeleton organizationNAS11998687 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
GO:0005622intracellularIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CDC42CDC42Hs | G25Kcell division cycle 42 (GTP binding protein, 25kDa)Biochemical ActivityBioGRID11432776 
PKN1DBK | MGC46204 | PAK1 | PKN | PKN-ALPHA | PRK1 | PRKCL1protein kinase N1-HPRD11432776 
PKN3RP11-545E17.1protein kinase N3Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID11432776 
PTK2FADK | FAK | FAK1 | pp125FAKPTK2 protein tyrosine kinase 2-HPRD,BioGRID8649427 
RHOAARH12 | ARHA | RHO12 | RHOH12ras homolog gene family, member ABiochemical ActivityBioGRID11432776 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ST_INTEGRIN_SIGNALING_PATHWAY 8262All SZGR genes in this pathway
PID_FAK_PATHWAY 5945All SZGR genes in this pathway
REACTOME_SIGNALING_BY_RHO_GTPASES 11381All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
HOOI_ST7_TARGETS_UP 9457All SZGR genes in this pathway
LIU_VMYB_TARGETS_UP 12778All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_UP 184125All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
MAYBURD_RESPONSE_TO_L663536_UP 2918All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_27 158All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN 4831All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN 12179All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_UP 6644All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
BRUECKNER_TARGETS_OF_MIRLET7A3_UP 11169All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN 5734All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_D_DN 7834All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_DN 204114All SZGR genes in this pathway
ZEMBUTSU_SENSITIVITY_TO_MITOMYCIN 1911All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_UP 12778All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
SERVITJA_LIVER_HNF1A_TARGETS_DN 157105All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
DURAND_STROMA_NS_UP 162103All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101619161971Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-144619061971A,m8hsa-miR-144UACAGUAUAGAUGAUGUACUAG
hsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-14534333439m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-17-5p/20/93.mr/106/519.d624062471A,m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-21419251Ahsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-26162916351Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-34/449123912461A,m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-37762046210m8hsa-miR-377AUCACACAAAGGCAACUUUUGU
miR-409-5p7057111Ahsa-miR-409-5pAGGUUACCCGAGCAACUUUGCA
miR-505163816451A,m8hsa-miR-505GUCAACACUUGCUGGUUUCCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.