Gene Page: FYN

Summary
GeneID  2534
Symbol  FYN
Synonyms  MGC45350|SLK|SYN
Description  FYN oncogene related to SRC, FGR, YES
See related  HGNC:4037|MIM:137025|Ensembl:ENSG00000010810|HPRD:00655|
Locus tag  RP1-66H14.1
Gene type  protein-coding
Map location  6q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.398 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 1.777 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
NDRG40.860.89
TTC7B0.850.86
CLPTM10.850.83
PLBD20.840.81
AP001107.10.830.86
CLSTN30.830.83
DCTN10.820.81
PINK10.820.86
C2CD2L0.820.85
ADAMTSL20.820.84
Top 10 negatively co-expressed genes
RBMX2-0.48-0.55
FAM159B-0.48-0.66
BCL7C-0.46-0.57
C21orf57-0.44-0.53
RPL31-0.44-0.50
RPL35-0.44-0.51
RPS20-0.43-0.55
C9orf46-0.43-0.50
RPL24-0.43-0.50
RPL13AP22-0.43-0.61
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIEA-
GO:0005524ATP bindingIEA-
GO:0004713protein tyrosine kinase activityIEA-
GO:0004715non-membrane spanning protein tyrosine kinase activityNAS7822789 
GO:0016740transferase activityIEA-
GO:0042802identical protein bindingIPI14993658 
GO:0030145manganese ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006468protein amino acid phosphorylationIEA-
GO:0006468protein amino acid phosphorylationNAS7822789 
GO:0007243protein kinase cascadeTAS1361685 
GO:0007631feeding behaviorTAS8264796 
GO:0007612learningTAS1361685 
GO:0006816calcium ion transportNAS7822789 
GO:0007275multicellular organismal developmentIEA-
GO:0050852T cell receptor signaling pathwayIDA7722293 
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP10858437 
GO:0005768endosomeIDA15611048 
GO:0005886plasma membraneIDA15611048 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADAM15MDC15ADAM metallopeptidase domain 15-HPRD,BioGRID11741929 
ADD2ADDBadducin 2 (beta)-HPRD,BioGRID11526103 
BCAR1CAS | CAS1 | CASS1 | CRKAS | P130Casbreast cancer anti-estrogen resistance 1-HPRD,BioGRID9188452 
BCL3BCL4 | D19S37B-cell CLL/lymphoma 3-HPRD,BioGRID9576921 
BTKAGMX1 | AT | ATK | BPK | IMD1 | MGC126261 | MGC126262 | PSCTK1 | XLABruton agammaglobulinemia tyrosine kinaseReconstituted ComplexBioGRID8058772 
CBLC-CBL | CBL2 | RNF55Cas-Br-M (murine) ecotropic retroviral transforming sequence-HPRD,BioGRID9535867 
CBLCCBL-3 | CBL-SL | RNF57Cas-Br-M (murine) ecotropic retroviral transforming sequence cAffinity Capture-Western
Reconstituted Complex
BioGRID10571044 
CD19B4 | MGC12802CD19 molecule-HPRD7589101 
CD2SRBC | T11CD2 molecule-HPRD,BioGRID9677430 
CD226DNAM-1 | DNAM1 | PTA1 | TLiSA1CD226 molecule-HPRD,BioGRID10591186 
CD2APCMS | DKFZp586H0519CD2-associated protein-HPRD10339567 
CD36CHDS7 | FAT | GP3B | GP4 | GPIV | PASIV | SCARB3CD36 molecule (thrombospondin receptor)-HPRD,BioGRID7521304 
CD44CDW44 | CSPG8 | ECMR-III | HCELL | IN | LHR | MC56 | MDU2 | MDU3 | MGC10468 | MIC4 | MUTCH-I | Pgp1CD44 molecule (Indian blood group)-HPRD,BioGRID9573028 
CD48BCM1 | BLAST | BLAST1 | MEM-102 | SLAMF2 | hCD48 | mCD48CD48 molecule-HPRD8104794 
CD55CR | CROM | DAF | TCCD55 molecule, decay accelerating factor for complement (Cromer blood group)-HPRD1385527 
CDC2CDC28A | CDK1 | DKFZp686L20222 | MGC111195cell division cycle 2, G1 to S and G2 to M-HPRD,BioGRID8910336 
CDH1Arc-1 | CD324 | CDHE | ECAD | LCAM | UVOcadherin 1, type 1, E-cadherin (epithelial)Affinity Capture-Western
Reconstituted Complex
BioGRID12640114 
CHRNA7CHRNA7-2 | NACHRA7cholinergic receptor, nicotinic, alpha 7Affinity Capture-WesternBioGRID11278378 
CNTN1F3 | GP135contactin 1-HPRD,BioGRID7595520 
CSF1RC-FMS | CD115 | CSFR | FIM2 | FMScolony stimulating factor 1 receptor-HPRD,BioGRID7681396 
CSKMGC117393c-src tyrosine kinase-HPRD,BioGRID8262983 
CTLA4CD152 | CELIAC3 | CTLA-4 | GSE | IDDM12cytotoxic T-lymphocyte-associated protein 4-HPRD,BioGRID9712716 
CTNNB1CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923catenin (cadherin-associated protein), beta 1, 88kDaBiochemical ActivityBioGRID12640114 
CTNND1CAS | CTNND | KIAA0384 | P120CAS | P120CTN | p120catenin (cadherin-associated protein), delta 1Affinity Capture-Western
Biochemical Activity
BioGRID12640114 |12835311 
CTNND2GT24 | NPRAPcatenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)-HPRD12835311 
DAG1156DAG | A3a | AGRNR | DAGdystroglycan 1 (dystrophin-associated glycoprotein 1)Affinity Capture-Western
Reconstituted Complex
BioGRID11724572 
DCCCRC18 | CRCR1deleted in colorectal carcinomaDCC interacts with Fyn.BIND15494732 
DLG4FLJ97752 | FLJ98574 | PSD95 | SAP90discs, large homolog 4 (Drosophila)-HPRD,BioGRID12419528 
DOK3DOKL | FLJ22570 | FLJ39939docking protein 3-HPRD10733577 
DOK4FLJ10488docking protein 4IRS5/DOK4 interacts with Fyn. This interaction was modelled on a demonstrated interaction between human IRS5/DOK4 and hamster Fyn.BIND12730241 
-HPRD12730241 
EPHA4HEK8 | SEK | TYRO1EPH receptor A4-HPRD,BioGRID12084815 
EPHA8EEK | HEK3 | KIAA1459EPH receptor A8-HPRD,BioGRID10498895 
EPHB3ETK2 | HEK2 | TYRO6EPH receptor B3-HPRD,BioGRID9674711 
EVLRNB6Enah/Vasp-like-HPRD10945997 
FASALPS1A | APO-1 | APT1 | CD95 | FAS1 | FASTM | TNFRSF6Fas (TNF receptor superfamily, member 6)-HPRD,BioGRID8626376 
FASLGAPT1LG1 | CD178 | CD95L | FASL | TNFSF6Fas ligand (TNF superfamily, member 6)-HPRD,BioGRID7589480 
FNBP4DKFZp686M14102 | DKFZp779I1064 | FBP30 | FLJ41904 | KIAA1014formin binding protein 4-HPRD,BioGRID10744724 
FYBADAP | PRO0823 | SLAP-130FYN binding protein (FYB-120/130)-HPRD7504057 |9207119 
-HPRD,BioGRID7504057 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID7687536 
GAB3-GRB2-associated binding protein 3-HPRD,BioGRID11739737 
GNB2L1Gnb2-rs1 | H12.3 | HLC-7 | PIG21 | RACK1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1-HPRD,BioGRID11943848 |12524444 
GP6GPIV | GPVI | MGC138168glycoprotein VI (platelet)-HPRD,BioGRID11943772 
GRB10GRB-IR | Grb-10 | IRBP | KIAA0207 | MEG1 | RSSgrowth factor receptor-bound protein 10-HPRD,BioGRID10871840 
GRIN2ANMDAR2A | NR2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2AAffinity Capture-Western
Reconstituted Complex
BioGRID9892651 |10458595 
|12419528 |12932824 
-HPRD10458595 |12932824 
GRIN2BMGC142178 | MGC142180 | NMDAR2B | NR2B | hNR3glutamate receptor, ionotropic, N-methyl D-aspartate 2B-HPRD,BioGRID10458595 
HNRNPKCSBP | FLJ41122 | HNRPK | TUNPheterogeneous nuclear ribonucleoprotein KFyn interacts with hnRNPK. This interaction was modeled on a demonstrated interaction between Fyn from an unspecified source and human hnRNPK.BIND8810341 
IL7RCD127 | CDW127 | IL-7R-alpha | IL7RA | ILRAinterleukin 7 receptor-HPRD,BioGRID7515933 
ITKEMT | LYK | MGC126257 | MGC126258 | PSCTK2IL2-inducible T-cell kinase-HPRD,BioGRID8810341 
JAK2JTK10Janus kinase 2 (a protein tyrosine kinase)-HPRD,BioGRID10551884 
KHDRBS1FLJ34027 | Sam68 | p62KH domain containing, RNA binding, signal transduction associated 1-HPRD,BioGRID9045636 
MAGGMA | S-MAG | SIGLEC-4A | SIGLEC4Amyelin associated glycoprotein-HPRD,BioGRID7525550 
MAP2DKFZp686I2148 | MAP2A | MAP2B | MAP2Cmicrotubule-associated protein 2Affinity Capture-WesternBioGRID11546790 
MAPTDDPAC | FLJ31424 | FTDP-17 | MAPTL | MGC138549 | MSTD | MTBT1 | MTBT2 | PPND | TAUmicrotubule-associated protein tau-HPRD,BioGRID11826099 
MCAMCD146 | MUC18melanoma cell adhesion molecule-HPRD,BioGRID9756930 
MS4A1B1 | Bp35 | CD20 | LEU-16 | MGC3969 | MS4A2 | S7membrane-spanning 4-domains, subfamily A, member 1-HPRD,BioGRID7545683 
NCAM1CD56 | MSK39 | NCAMneural cell adhesion molecule 1-HPRD9079653 |11839780 
NEDD9CAS-L | CAS2 | CASL | CASS2 | HEF1 | dJ49G10.2 | dJ761I2.1neural precursor cell expressed, developmentally down-regulated 9-HPRD,BioGRID9360983 
NMT1NMTN-myristoyltransferase 1Biochemical ActivityBioGRID11594778 
NPHS1CNF | NPHNnephrosis 1, congenital, Finnish type (nephrin)-HPRD,BioGRID12668668 |12846735 
NTRK2GP145-TrkB | TRKBneurotrophic tyrosine kinase, receptor, type 2-HPRD,BioGRID9648856 
PAG1CBP | FLJ37858 | MGC138364 | PAGphosphoprotein associated with glycosphingolipid microdomains 1-HPRD,BioGRID10790433 
PDE4DDPDE3 | HSPDE4D | PDE4DN2 | STRK1phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)PDE4D4 interacts with Fyn SH3 domain.BIND10571082 
PDGFRBCD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1platelet-derived growth factor receptor, beta polypeptide-HPRD1696179 
PECAM1CD31 | PECAM-1platelet/endothelial cell adhesion molecule-HPRD,BioGRID10858437 
PIK3R1GRB1 | p85 | p85-ALPHAphosphoinositide-3-kinase, regulatory subunit 1 (alpha)-HPRD8394019 
Reconstituted ComplexBioGRID8294442 
PIK3R2P85B | p85 | p85-BETAphosphoinositide-3-kinase, regulatory subunit 2 (beta)-HPRD,BioGRID1334406 
PLAURCD87 | UPAR | URKRplasminogen activator, urokinase receptor-HPRD9417082 
PLCG1PLC-II | PLC1 | PLC148 | PLCgamma1phospholipase C, gamma 1-HPRD10586033 
PLCG2-phospholipase C, gamma 2 (phosphatidylinositol-specific)-HPRD,BioGRID8395016 
PLD2-phospholipase D2-HPRD12697812 
PRKCQMGC126514 | MGC141919 | PRKCT | nPKC-thetaprotein kinase C, theta-HPRD,BioGRID10383400 
PTK2FADK | FAK | FAK1 | pp125FAKPTK2 protein tyrosine kinase 2-HPRD,BioGRID11278857 
PTK2BCADTK | CAKB | FADK2 | FAK2 | FRNK | PKB | PTK | PYK2 | RAFTKPTK2B protein tyrosine kinase 2 beta-HPRD,BioGRID9091579 |9104812 
|10867021 
PTPN11BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2protein tyrosine phosphatase, non-receptor type 11-HPRD,BioGRID10212213 
PTPN5FLJ14427 | PTPSTEP | STEPprotein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)-HPRD,BioGRID11983687 
PTPRAHEPTP | HLPR | HPTPA | HPTPalpha | LRP | PTPA | PTPRL2 | R-PTP-alpha | RPTPAprotein tyrosine phosphatase, receptor type, A-HPRD,BioGRID9535845 
PTPRCB220 | CD45 | CD45R | GP180 | LCA | LY5 | T200protein tyrosine phosphatase, receptor type, C-HPRD9368621 |12589038 
PXNFLJ16691paxillin-HPRD,BioGRID10804218 
RAF1CRAF | NS5 | Raf-1 | c-Rafv-raf-1 murine leukemia viral oncogene homolog 1-HPRD,BioGRID7517401 
RICSGC-GAP | GRIT | KIAA0712 | MGC1892 | p200RhoGAP | p250GAPRho GTPase-activating protein-HPRD,BioGRID12788081 |12857875 
RPL10DKFZp686J1851 | DXS648 | DXS648E | FLJ23544 | FLJ27072 | NOV | QMribosomal protein L10Reconstituted ComplexBioGRID12138090 
SDC3N-syndecan | SDCN | SYND3syndecan 3-HPRD,BioGRID9553134 
SH2B2APSSH2B adaptor protein 2-HPRD10872802 
SH2D1ADSHP | EBVS | FLJ18687 | FLJ92177 | IMD5 | LYP | MTCP1 | SAP | XLP | XLPDSH2 domain protein 1A-HPRD,BioGRID12545174 
SH3BP23BP2 | CRBM | CRPM | FLJ42079 | RES4-23SH3-domain binding protein 2Two-hybridBioGRID9846481 
SIT1MGC125908 | MGC125909 | MGC125910 | RP11-331F9.5 | SITsignaling threshold regulating transmembrane adaptor 1-HPRD,BioGRID10209036 
SKAP1SCAP1 | SKAP55src kinase associated phosphoprotein 1-HPRD,BioGRID9195899 
SKAP2MGC10411 | MGC33304 | PRAP | RA70 | SAPS | SCAP2 | SKAP-HOM | SKAP55Rsrc kinase associated phosphoprotein 2-HPRD,BioGRID9837776 
SLAMF1CD150 | CDw150 | SLAMsignaling lymphocytic activation molecule family member 1Reconstituted ComplexBioGRID12545174 
SNCAMGC110988 | NACP | PARK1 | PARK4 | PD1synuclein, alpha (non A4 component of amyloid precursor)-HPRD,BioGRID11162638 
SOCS1CIS1 | CISH1 | JAB | SOCS-1 | SSI-1 | SSI1 | TIP3suppressor of cytokine signaling 1Socs1 interacts with Fyn. This interaction was modeled on a demonstrated interaction between mouse Socs1 and Fyn from an unspecified species.BIND10022833 
-HPRD,BioGRID10022833 
SOS1GF1 | GGF1 | GINGF | HGF | NS4son of sevenless homolog 1 (Drosophila)-HPRD,BioGRID9856337 
SPNCD43 | GPL115 | LSNsialophorin-HPRD9603925 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)Protein-peptideBioGRID9169421 
SYKDKFZp313N1010 | FLJ25043 | FLJ37489spleen tyrosine kinase-HPRD,BioGRID9535867 
THY1CD90 | FLJ33325Thy-1 cell surface antigen-HPRD,BioGRID1351058 
TNK2ACK | ACK1 | FLJ44758 | FLJ45547 | p21cdc42Hstyrosine kinase, non-receptor, 2-HPRD,BioGRID11087735 
TOM1L1OK/KNS-CL.3 | SRCASMtarget of myb1 (chicken)-like 1Reconstituted ComplexBioGRID11711534 
TRAT1HSPC062 | TCRIM | TRIMT cell receptor associated transmembrane adaptor 1Reconstituted ComplexBioGRID10790433 
TRPC6FLJ11098 | FLJ14863 | FSGS2 | TRP6transient receptor potential cation channel, subfamily C, member 6-HPRD,BioGRID14761972 
TRPV4OTRPC4 | TRP12 | VR-OAC | VRL-2 | VRL2 | VROACtransient receptor potential cation channel, subfamily V, member 4-HPRD,BioGRID12538589 
TUBA1BK-ALPHA-1tubulin, alpha 1b-HPRD11826099 
TUBA3CTUBA2 | bA408E5.3tubulin, alpha 3c-HPRD,BioGRID8566014 |11826099 
TUBA4AFLJ30169 | H2-ALPHA | TUBA1tubulin, alpha 4a-HPRD8566014 
TYK2JTK1tyrosine kinase 2-HPRD,BioGRID9196040 
TYRO3BYK | Brt | Dtk | FLJ16467 | RSE | Sky | TifTYRO3 protein tyrosine kinase-HPRD7537495 
UNC119HRG4unc-119 homolog (C. elegans)-HPRD,BioGRID14757743 
VAV1VAVvav 1 guanine nucleotide exchange factor-HPRD,BioGRID9822663 
WASIMD2 | THC | WASPWiskott-Aldrich syndrome (eczema-thrombocytopenia)Affinity Capture-Western
Reconstituted Complex
BioGRID8805332 |10532312 
-HPRD8805332 |10224664 
|10532312 
WASF1FLJ31482 | KIAA0269 | SCAR1 | WAVE | WAVE1WAS protein family, member 1-HPRD10532312 
WASF2SCAR2 | WAVE2 | dJ393P12.2WAS protein family, member 2-HPRD10532312 
YES1HsT441 | P61-YES | Yes | c-yesv-yes-1 Yamaguchi sarcoma viral oncogene homolog 1Affinity Capture-WesternBioGRID12640114 
YTHDC1KIAA1966 | YT521 | YT521-BYTH domain containing 1-HPRD,BioGRID15175272 
ZAP70FLJ17670 | FLJ17679 | SRK | STD | TZK | ZAP-70zeta-chain (TCR) associated protein kinase 70kDa-HPRD,BioGRID7760813 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AXON_GUIDANCE 129103All SZGR genes in this pathway
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_ADHERENS_JUNCTION 7553All SZGR genes in this pathway
KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 13792All SZGR genes in this pathway
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 10889All SZGR genes in this pathway
KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY 7958All SZGR genes in this pathway
KEGG_PRION_DISEASES 3528All SZGR genes in this pathway
KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 5936All SZGR genes in this pathway
KEGG_VIRAL_MYOCARDITIS 7358All SZGR genes in this pathway
BIOCARTA_BIOPEPTIDES_PATHWAY 4535All SZGR genes in this pathway
BIOCARTA_EPHA4_PATHWAY 108All SZGR genes in this pathway
BIOCARTA_ECM_PATHWAY 2417All SZGR genes in this pathway
BIOCARTA_IL7_PATHWAY 1714All SZGR genes in this pathway
BIOCARTA_INTEGRIN_PATHWAY 3829All SZGR genes in this pathway
BIOCARTA_TCRA_PATHWAY 1310All SZGR genes in this pathway
BIOCARTA_TCR_PATHWAY 4937All SZGR genes in this pathway
ST_INTEGRIN_SIGNALING_PATHWAY 8262All SZGR genes in this pathway
PID_FCER1_PATHWAY 6243All SZGR genes in this pathway
PID_ERBB4_PATHWAY 3832All SZGR genes in this pathway
PID_GLYPICAN_1PATHWAY 2720All SZGR genes in this pathway
PID_TCR_PATHWAY 6651All SZGR genes in this pathway
PID_PTP1B_PATHWAY 5240All SZGR genes in this pathway
PID_REELIN_PATHWAY 2929All SZGR genes in this pathway
PID_P38_ALPHA_BETA_PATHWAY 3125All SZGR genes in this pathway
PID_CD8_TCR_PATHWAY 5342All SZGR genes in this pathway
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY 5041All SZGR genes in this pathway
PID_TXA2PATHWAY 5743All SZGR genes in this pathway
PID_NETRIN_PATHWAY 3227All SZGR genes in this pathway
PID_IL2_1PATHWAY 5543All SZGR genes in this pathway
PID_CXCR4_PATHWAY 10278All SZGR genes in this pathway
PID_PI3KCI_PATHWAY 4940All SZGR genes in this pathway
PID_AJDISS_2PATHWAY 4838All SZGR genes in this pathway
PID_AMB2_NEUTROPHILS_PATHWAY 4132All SZGR genes in this pathway
PID_EPHA_FWDPATHWAY 3429All SZGR genes in this pathway
PID_ECADHERIN_KERATINOCYTE_PATHWAY 2119All SZGR genes in this pathway
PID_PDGFRB_PATHWAY 129103All SZGR genes in this pathway
PID_NEPHRIN_NEPH1_PATHWAY 3124All SZGR genes in this pathway
PID_VEGFR1_2_PATHWAY 6957All SZGR genes in this pathway
PID_SYNDECAN_3_PATHWAY 1715All SZGR genes in this pathway
PID_EPHRINB_REV_PATHWAY 3025All SZGR genes in this pathway
PID_ALPHA_SYNUCLEIN_PATHWAY 3325All SZGR genes in this pathway
PID_FAK_PATHWAY 5945All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT 7859All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_CELL_CELL_COMMUNICATION 12077All SZGR genes in this pathway
REACTOME_REGULATION_OF_KIT_SIGNALING 1710All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB2 10178All SZGR genes in this pathway
REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS 2924All SZGR genes in this pathway
REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 12690All SZGR genes in this pathway
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 9165All SZGR genes in this pathway
REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN 128All SZGR genes in this pathway
REACTOME_PECAM1_INTERACTIONS 107All SZGR genes in this pathway
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE 3125All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH 6449All SZGR genes in this pathway
REACTOME_CD28_CO_STIMULATION 3226All SZGR genes in this pathway
REACTOME_CRMPS_IN_SEMA3A_SIGNALING 1414All SZGR genes in this pathway
REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION 1514All SZGR genes in this pathway
REACTOME_CD28_DEPENDENT_VAV1_PATHWAY 1110All SZGR genes in this pathway
REACTOME_SEMAPHORIN_INTERACTIONS 6853All SZGR genes in this pathway
REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION 139All SZGR genes in this pathway
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY 6348All SZGR genes in this pathway
REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING 2218All SZGR genes in this pathway
REACTOME_CTLA4_INHIBITORY_SIGNALING 2115All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ILS 10786All SZGR genes in this pathway
REACTOME_NETRIN1_SIGNALING 4130All SZGR genes in this pathway
REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING 1311All SZGR genes in this pathway
REACTOME_REGULATION_OF_SIGNALING_BY_CBL 1816All SZGR genes in this pathway
REACTOME_NEPHRIN_INTERACTIONS 2015All SZGR genes in this pathway
REACTOME_IL_3_5_AND_GM_CSF_SIGNALING 4334All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_HIV_INFECTION 207122All SZGR genes in this pathway
REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 13281All SZGR genes in this pathway
REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS 2819All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 270204All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
LIU_VMYB_TARGETS_UP 12778All SZGR genes in this pathway
RODRIGUES_DCC_TARGETS_DN 12184All SZGR genes in this pathway
BILBAN_B_CLL_LPL_DN 4225All SZGR genes in this pathway
AKL_HTLV1_INFECTION_DN 6841All SZGR genes in this pathway
ELVIDGE_HYPOXIA_UP 171112All SZGR genes in this pathway
ELVIDGE_HYPOXIA_BY_DMOG_UP 13085All SZGR genes in this pathway
ELVIDGE_HIF1A_TARGETS_DN 9158All SZGR genes in this pathway
ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN 10472All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_UP 14984All SZGR genes in this pathway
PROVENZANI_METASTASIS_UP 194112All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE 4931All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_1 5133All SZGR genes in this pathway
XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP 3520All SZGR genes in this pathway
WANG_METHYLATED_IN_BREAST_CANCER 3525All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN 164111All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
WU_CELL_MIGRATION 184114All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
DING_LUNG_CANCER_MUTATED_FREQUENTLY 1210All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD1_UP 4529All SZGR genes in this pathway
NADLER_HYPERGLYCEMIA_AT_OBESITY 5835All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_DN 178121All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_DN 318220All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_DN 3225All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
YIH_RESPONSE_TO_ARSENITE_C3 3624All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G6 153112All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN 161105All SZGR genes in this pathway
SAFFORD_T_LYMPHOCYTE_ANERGY 8754All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D8 4029All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 271175All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_12HR_DN 10164All SZGR genes in this pathway
KRIGE_AMINO_ACID_DEPRIVATION 2920All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_UP 299167All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN 315197All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
PODAR_RESPONSE_TO_ADAPHOSTIN_UP 14798All SZGR genes in this pathway
LU_TUMOR_ANGIOGENESIS_UP 2522All SZGR genes in this pathway
FIRESTEIN_PROLIFERATION 175125All SZGR genes in this pathway
JIANG_TIP30_TARGETS_UP 4628All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE 346192All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_DN 235144All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
VALK_AML_CLUSTER_11 3624All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_DN 18197All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G123_DN 5130All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
NAKAMURA_ADIPOGENESIS_EARLY_UP 6644All SZGR genes in this pathway
WHITFIELD_CELL_CYCLE_G2_M 216124All SZGR genes in this pathway
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP 242159All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP 259159All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-271861921Ahsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-369-3p387393m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-96295301m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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