Gene Page: GCA

Summary
GeneID  25801
Symbol  GCA
Synonyms  GCL
Description  grancalcin, EF-hand calcium binding protein
See related  HGNC:15990|MIM:607030|Ensembl:ENSG00000115271|HPRD:06122|
Locus tag  -
Gene type  protein-coding
Map location  2q24.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02395 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZBTB380.910.95
VCPIP10.910.94
SEL1L0.900.93
KIAA12190.900.94
BMPR20.890.92
MYO9A0.890.92
LPGAT10.890.93
MEGF90.890.93
CPEB40.880.94
ATRN0.880.93
Top 10 negatively co-expressed genes
RAB34-0.61-0.71
S100A16-0.61-0.70
DBI-0.61-0.73
RHOC-0.59-0.70
SERPINB6-0.59-0.66
FXYD1-0.59-0.69
HIGD1B-0.59-0.72
HSD17B14-0.58-0.67
ACSF2-0.58-0.67
METRN-0.58-0.71
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingTAS1530588 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006944membrane fusionTAS1530588 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmTAS1530588 
GO:0005886plasma membraneTAS1530588 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
LCP1CP64 | DKFZp781A23186 | FLJ25423 | FLJ26114 | FLJ39956 | L-PLASTIN | LC64P | LPL | PLS2lymphocyte cytosolic protein 1 (L-plastin)-HPRD,BioGRID10903868 |11279160 
SRIFLJ26259 | SCNsorcinSorcin interacts with grancalcin to form a heterodimer.BIND12804766 
-HPRD,BioGRID12804766 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP 3925All SZGR genes in this pathway
WANG_CLIM2_TARGETS_DN 186114All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN 536332All SZGR genes in this pathway
SCIBETTA_KDM5B_TARGETS_DN 8155All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN 199124All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP 177113All SZGR genes in this pathway
COLDREN_GEFITINIB_RESISTANCE_DN 230115All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_3_UP 329196All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP 9760All SZGR genes in this pathway
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP 5232All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_DN 9751All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_DN 10359All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
CHUNG_BLISTER_CYTOTOXICITY_DN 4429All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_DN 252155All SZGR genes in this pathway
MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN 6746All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_UP 266142All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_DN 428246All SZGR genes in this pathway


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