Gene Page: GMPR

Summary
GeneID  2766
Symbol  GMPR
Synonyms  GMPR1
Description  guanosine monophosphate reductase
See related  HGNC:4376|MIM:139265|Ensembl:ENSG00000137198|HPRD:00754|
Locus tag  RP3-467D16.2
Gene type  protein-coding
Map location  6p23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LRWD10.930.94
MRPS20.930.92
GPR172A0.930.94
WDR540.920.93
PTOV10.920.93
POLD20.910.93
EMD0.910.92
WDR180.910.92
ZNF4080.910.92
TARBP20.910.92
Top 10 negatively co-expressed genes
AF347015.27-0.72-0.82
AF347015.33-0.71-0.81
MT-CO2-0.71-0.79
AF347015.8-0.70-0.80
AF347015.31-0.70-0.78
MT-CYB-0.68-0.79
AF347015.15-0.67-0.78
AF347015.2-0.66-0.80
AF347015.26-0.65-0.79
C5orf53-0.63-0.68
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003920GMP reductase activityTAS9813009 
GO:0016491oxidoreductase activityIEA-
GO:0030955potassium ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009117nucleotide metabolic processIEA-
GO:0009409response to coldTAS9813009 
GO:0055114oxidation reductionIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PURINE_METABOLISM 15996All SZGR genes in this pathway
REACTOME_METABOLISM_OF_NUCLEOTIDES 7245All SZGR genes in this pathway
REACTOME_PURINE_SALVAGE 1311All SZGR genes in this pathway
REACTOME_PURINE_METABOLISM 3324All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP 182110All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP 194122All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN 187115All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
ROVERSI_GLIOMA_LOH_REGIONS 4430All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
DER_IFN_ALPHA_RESPONSE_UP 7448All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_UP 205126All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_DN 169112All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_UP 203130All SZGR genes in this pathway
VERHAAK_AML_WITH_NPM1_MUTATED_DN 246180All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
BROWNE_INTERFERON_RESPONSIVE_GENES 6844All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_DN 2915All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
ZHU_CMV_8_HR_UP 4739All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP 295149All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING 246152All SZGR genes in this pathway
EHLERS_ANEUPLOIDY_DN 128All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
LOPEZ_MESOTHELIOMA_SURVIVAL_UP 119All SZGR genes in this pathway
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP 13485All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_UP 266142All SZGR genes in this pathway
LIM_MAMMARY_LUMINAL_MATURE_UP 11665All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.