Gene Page: GRHL1

Summary
GeneID  29841
Symbol  GRHL1
Synonyms  LBP-32|LBP32|MGR|TFCP2L2
Description  grainyhead-like 1 (Drosophila)
See related  HGNC:17923|MIM:609786|Ensembl:ENSG00000134317|HPRD:18176|
Locus tag  -
Gene type  protein-coding
Map location  2p25.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.81 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MAP2K70.790.83
LZTS20.790.84
NACAD0.750.77
PHLDB10.740.82
CC2D1B0.740.77
DNM20.730.80
PLEKHM10.730.74
UNC84B0.720.79
SYVN10.720.76
DPP90.710.75
Top 10 negatively co-expressed genes
CARD16-0.47-0.53
AF347015.21-0.47-0.55
SYCP3-0.46-0.52
AF347015.31-0.46-0.50
CLEC2B-0.45-0.51
C1orf54-0.45-0.50
LY96-0.44-0.51
C1orf61-0.44-0.41
CXCL14-0.44-0.47
GPR160-0.44-0.44
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0007275multicellular organismal developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIDA18029348 
GO:0005634nucleusIEA-
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRHL3MGC46624 | SOM | TFCP2L4grainyhead-like 3 (Drosophila)-HPRD,BioGRID12549979 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 10472All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 168115All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP 450256All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_UP 14175All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_UP 14984All SZGR genes in this pathway
COLDREN_GEFITINIB_RESISTANCE_DN 230115All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_UP 214144All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_UP 11668All SZGR genes in this pathway
LASTOWSKA_COAMPLIFIED_WITH_MYCN 4329All SZGR genes in this pathway
TAGHAVI_NEOPLASTIC_TRANSFORMATION 1210All SZGR genes in this pathway
GEORGES_TARGETS_OF_MIR192_AND_MIR215 893528All SZGR genes in this pathway
LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT 10873All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_DN 8251All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_DN 428246All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-125/351133213381Ahsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-192/21513461352m8hsa-miR-192CUGACCUAUGAAUUGACAGCC
hsa-miR-215AUGACCUAUGAAUUGACAGAC
miR-25/32/92/363/3676596661A,m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-299-5p153215381Ahsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
miR-30-5p527533m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-331124912551Ahsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-3816496551Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-915351541m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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