Gene Page: HP

Summary
GeneID  3240
Symbol  HP
Synonyms  BP|HP2-ALPHA-2|HPA1S|MGC111141
Description  haptoglobin
See related  HGNC:5141|MIM:140100|Ensembl:ENSG00000197711|HPRD:00772|
Locus tag  -
Gene type  protein-coding
Map location  16q22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 31 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityIEAglutamate (GO term level: 7)-
GO:0003824catalytic activityIEA-
GO:0030492hemoglobin bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisIEA-
GO:0006952defense responseTAS7036344 
GO:0006879cellular iron ion homeostasisNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005576extracellular regionNAS14718574 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD163M130 | MM130CD163 molecule-HPRD11854028 
CD22FLJ22814 | MGC130020 | SIGLEC-2 | SIGLEC2CD22 molecule-HPRD11967116 
HBBCD113t-Chemoglobin, beta-HPRD,BioGRID7378053 
ITGAMCD11B | CR3A | MAC-1 | MAC1A | MGC117044 | MO1A | SLEB6integrin, alpha M (complement component 3 receptor 3 subunit)-HPRD11967116 
ITGB2CD18 | LAD | LCAMB | LFA-1 | MAC-1 | MF17 | MFI7integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)-HPRD11967116 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN 14383All SZGR genes in this pathway
LOPEZ_MESOTELIOMA_SURVIVAL_TIME_DN 77All SZGR genes in this pathway
BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_UP 3019All SZGR genes in this pathway
LOPEZ_MESOTHELIOMA_SURVIVAL_WORST_VS_BEST_DN 76All SZGR genes in this pathway
BIDUS_METASTASIS_DN 16193All SZGR genes in this pathway
HAHTOLA_SEZARY_SYNDROM_UP 9858All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_UP 215137All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_3_4WK_DN 3927All SZGR genes in this pathway
WONG_ENDMETRIUM_CANCER_UP 2517All SZGR genes in this pathway
HUMMERICH_SKIN_CANCER_PROGRESSION_DN 10064All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2 12792All SZGR genes in this pathway
LI_LUNG_CANCER 4130All SZGR genes in this pathway
HOUSTIS_ROS 3629All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
NADLER_OBESITY_DN 4834All SZGR genes in this pathway
GERY_CEBP_TARGETS 12690All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
RUAN_RESPONSE_TO_TNF_UP 1210All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
RUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP 1711All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_DN 9671All SZGR genes in this pathway
BURTON_ADIPOGENESIS_6 189112All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_UP 15692All SZGR genes in this pathway
ZHENG_IL22_SIGNALING_UP 5636All SZGR genes in this pathway
CADWELL_ATG16L1_TARGETS_UP 9356All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_DN 252155All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_DN 4934All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_PCA1_UP 10166All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 6850All SZGR genes in this pathway
KAMIKUBO_MYELOID_CEBPA_NETWORK 2819All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
STEGER_ADIPOGENESIS_UP 2116All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
VERNOCHET_ADIPOGENESIS 1911All SZGR genes in this pathway
HUANG_GATA2_TARGETS_UP 14996All SZGR genes in this pathway


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