Gene Page: EIF3E

Summary
GeneID  3646
Symbol  EIF3E
Synonyms  EIF3-P48|EIF3S6|INT6|eIF3-p46
Description  eukaryotic translation initiation factor 3, subunit E
See related  HGNC:3277|MIM:602210|Ensembl:ENSG00000104408|HPRD:03734|
Locus tag  -
Gene type  protein-coding
Map location  8q22-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0018 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COL3A10.780.27
LUM0.780.69
C70.760.83
ITIH20.760.71
OGN0.750.83
OSR10.750.66
COL1A10.740.50
OLFML30.740.54
CYP1B10.740.81
COL6A30.730.80
Top 10 negatively co-expressed genes
AC007216.4-0.24-0.20
AF347015.21-0.240.05
SNHG12-0.24-0.47
CHMP4A-0.23-0.33
AC098691.2-0.22-0.04
AC010300.1-0.22-0.27
AF347015.18-0.22-0.03
AC005921.3-0.21-0.45
MT-CO2-0.210.06
AF347015.26-0.210.09
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003743translation initiation factor activityTAS9295280 
GO:0005515protein bindingIPI14667819 |17220478 |17324924 
|17353931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006446regulation of translational initiationTAS9295280 
GO:0006412translationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP12588972 
GO:0005852eukaryotic translation initiation factor 3 complexTAS9295280 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BAT2D6S51 | D6S51E | DKFZp686D09175 | G2HLA-B associated transcript 2-HPRD,BioGRID14667819 
CNTFHCNTFciliary neurotrophic factorAffinity Capture-MSBioGRID17353931 
COPS6CSN6 | MOV34-34KDCOP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)-HPRD,BioGRID12220626 
COPS7AMGC110877COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)-HPRD12220626 
COPS7BFLJ12612 | MGC111077COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)-HPRD12220626 
COPS8COP9 | CSN8 | MGC1297 | MGC43256 | SGN8COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)-HPRD12220626 
CSN3CSN10 | CSNK | KCAcasein kappaAffinity Capture-Western
Two-hybrid		BioGRID12220626 
DDX24-DEAD (Asp-Glu-Ala-Asp) box polypeptide 24Two-hybridBioGRID16169070 
EIF1BGC20eukaryotic translation initiation factor 1BAffinity Capture-MSBioGRID17353931 
EIF3AEIF3 | EIF3S10 | KIAA0139 | P167 | TIF32 | eIF3-p170 | eIF3-theta | p180 | p185eukaryotic translation initiation factor 3, subunit AAffinity Capture-MS
Affinity Capture-Western
Co-purification		BioGRID11590142 |14519125 
|17353931 
EIF3CEIF3S8 | FLJ78287 | MGC189744 | eIF3-p110eukaryotic translation initiation factor 3, subunit C-HPRD,BioGRID10504338 
EIF3EIPEIF3S11 | EIF3S6IP | HSPC021 | HSPC025 | MSTP005eukaryotic translation initiation factor 3, subunit E interacting protein-HPRD,BioGRID11590142 
GPAA1GAA1 | hGAA1glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)Two-hybridBioGRID16169070 
GPBP1L1RP11-767N6.1 | SP192GC-rich promoter binding protein 1-like 1Two-hybridBioGRID16189514 
HAP1HAP2 | HIP5 | HLP | hHLP1huntingtin-associated protein 1Two-hybridBioGRID16169070 
IFIT1G10P1 | GARG-16 | IFI-56 | IFI56 | IFNAI1 | ISG56 | RNM561interferon-induced protein with tetratricopeptide repeats 1-HPRD,BioGRID10644362 
MAGED1DLXIN-1 | NRAGEmelanoma antigen family D, 1Affinity Capture-MSBioGRID17353931 
NSFSKD2N-ethylmaleimide-sensitive factorTwo-hybridBioGRID16169070 
RGS2G0S8regulator of G-protein signaling 2, 24kDaAffinity Capture-MSBioGRID17353931 
RUNDC3ARAP2IP | RPIP8RUN domain containing 3ATwo-hybridBioGRID16189514 
SAP182HOR0202 | MGC27131 | SAP18pSin3A-associated protein, 18kDaAffinity Capture-MSBioGRID17353931 
TRIM27RFP | RNF76tripartite motif-containing 27-HPRD10504338 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_HIF2PATHWAY 3429All SZGR genes in this pathway
REACTOME_TRANSLATION 22275All SZGR genes in this pathway
REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 7424All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 8430All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 17651All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_3_DN 229142All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_UP 584356All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
DER_IFN_GAMMA_RESPONSE_DN 119All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_DN 14192All SZGR genes in this pathway
KIM_LRRC3B_TARGETS 3024All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP 285167All SZGR genes in this pathway
NUTT_GBM_VS_AO_GLIOMA_DN 4522All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
MILI_PSEUDOPODIA 4327All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_UP 7445All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP 518299All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_DN 18197All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 7645All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
BILANGES_SERUM_SENSITIVE_GENES 9054All SZGR genes in this pathway
BILANGES_RAPAMYCIN_SENSITIVE_VIA_TSC1_AND_TSC2 7337All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_DN 553343All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.