AKT1 | AKT | MGC99656 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 | - | HPRD,BioGRID | 10497255 |
ALK | CD246 | Ki-1 | TFG/ALK | anaplastic lymphoma receptor tyrosine kinase | - | HPRD | 9174053 |
AP3S1 | CLAPS3 | Sigma3A | adaptor-related protein complex 3, sigma 1 subunit | - | HPRD,BioGRID | 9792713 |
ATP2A1 | ATP2A | SERCA1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | - | HPRD | 9295312 |
BCL2 | Bcl-2 | B-cell CLL/lymphoma 2 | Affinity Capture-Western | BioGRID | 10679027 |
BCL2L1 | BCL-XL/S | BCL2L | BCLX | Bcl-X | DKFZp781P2092 | bcl-xL | bcl-xS | BCL2-like 1 | - | HPRD,BioGRID | 10679027 |
CDH1 | Arc-1 | CD324 | CDHE | ECAD | LCAM | UVO | cadherin 1, type 1, E-cadherin (epithelial) | - | HPRD | 11035789 |
CHUK | IKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16 | conserved helix-loop-helix ubiquitous kinase | - | HPRD,BioGRID | 12351658 |
FRAP1 | FLJ44809 | FRAP | FRAP2 | MTOR | RAFT1 | RAPT1 | FK506 binding protein 12-rapamycin associated protein 1 | Affinity Capture-Western | BioGRID | 11287630 |
GRB10 | GRB-IR | Grb-10 | IRBP | KIAA0207 | MEG1 | RSS | growth factor receptor-bound protein 10 | Reconstituted Complex | BioGRID | 8621530 |
GRB2 | ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084 | growth factor receptor-bound protein 2 | - | HPRD | 7488107 |
Affinity Capture-Western Reconstituted Complex | BioGRID | 8491186 |8536716 |12173038 |
IGF1R | CD221 | IGFIR | JTK13 | MGC142170 | MGC142172 | MGC18216 | insulin-like growth factor 1 receptor | IGFIR interacts with IRS-1. | BIND | 7541045 |
IRS-1 interacts with IGF-IR. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human IGF-IR. | BIND | 10026153 |
- | HPRD,BioGRID | 7559507 |
IKBKB | FLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | Affinity Capture-Western | BioGRID | 12351658 |
IKBKG | AMCBX1 | FIP-3 | FIP3 | Fip3p | IKK-gamma | IP | IP1 | IP2 | IPD2 | NEMO | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | - | HPRD | 12351658 |
IL4R | CD124 | IL4RA | interleukin 4 receptor | - | HPRD,BioGRID | 8599766 |
INSR | CD220 | HHF5 | insulin receptor | IRS-1 interacts with IR. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human IR. | BIND | 10026153 |
Insulin Receptor Substrate-1 Binds to the Insulin Receptor. This interaction is modeled on demonstrated interaction between human IR and rat IRS-1 | BIND | 8626379 |
- | HPRD,BioGRID | 11606564 |
JAK1 | JAK1A | JAK1B | JTK3 | Janus kinase 1 (a protein tyrosine kinase) | Affinity Capture-Western Biochemical Activity | BioGRID | 7499365 |9492017
|
JAK2 | JTK10 | Janus kinase 2 (a protein tyrosine kinase) | Affinity Capture-Western Biochemical Activity | BioGRID | 9492017 |11208867
|
JAK3 | JAK-3 | JAK3_HUMAN | JAKL | L-JAK | LJAK | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | - | HPRD,BioGRID | 7499365 |
KHDRBS1 | FLJ34027 | Sam68 | p62 | KH domain containing, RNA binding, signal transduction associated 1 | Affinity Capture-Western | BioGRID | 11604231 |
MAPK8 | JNK | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1 | mitogen-activated protein kinase 8 | - | HPRD,BioGRID | 10722755 |11606564 |12417588 |
MAPK9 | JNK-55 | JNK2 | JNK2A | JNK2ALPHA | JNK2B | JNK2BETA | PRKM9 | SAPK | p54a | p54aSAPK | mitogen-activated protein kinase 9 | - | HPRD | 12417588 |
NISCH | FLJ14425 | FLJ40413 | FLJ90519 | I-1 | IRAS | KIAA0975 | nischarin | Affinity Capture-Western | BioGRID | 11912194 |
PHIP | FLJ20705 | FLJ45918 | MGC90216 | WDR11 | ndrp | pleckstrin homology domain interacting protein | - | HPRD | 11018022 |
PIK3CA | MGC142161 | MGC142163 | PI3K | p110-alpha | phosphoinositide-3-kinase, catalytic, alpha polypeptide | Affinity Capture-Western | BioGRID | 16354680 |
PIK3R1 | GRB1 | p85 | p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | Affinity Capture-Western Far Western | BioGRID | 1381348 |12107746 |12173038 |12730242
|
- | HPRD | 1381348 |12173038
|
- | HPRD | 12220227 |
PIK3R2 | P85B | p85 | p85-BETA | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | IRS-1 interacts with p85-beta. This interaction was modeled based on a demonstrated interaction between IRS-1 from an unspecified species and p85-beta from an unknown species. | BIND | 11172806 |
- | HPRD | 11120660 |
PIK3R3 | DKFZp686P05226 | FLJ41892 | p55 | p55-GAMMA | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | - | HPRD,BioGRID | 7542745 |9415396 |10417350 |
PRKCD | MAY1 | MGC49908 | PKCD | nPKC-delta | protein kinase C, delta | - | HPRD,BioGRID | 12031982 |
PTK2 | FADK | FAK | FAK1 | pp125FAK | PTK2 protein tyrosine kinase 2 | - | HPRD,BioGRID | 9822703 |
PTPN1 | PTP1B | protein tyrosine phosphatase, non-receptor type 1 | - | HPRD,BioGRID | 10660596 |
PTPN11 | BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2 | protein tyrosine phosphatase, non-receptor type 11 | - | HPRD,BioGRID | 8505282 |9756938
|
PTPRC | B220 | CD45 | CD45R | GP180 | LCA | LY5 | T200 | protein tyrosine phosphatase, receptor type, C | - | HPRD,BioGRID | 8557683 |
PTPRF | FLJ43335 | FLJ45062 | FLJ45567 | LAR | protein tyrosine phosphatase, receptor type, F | - | HPRD | 10660596 |
SFN | YWHAS | stratifin | Affinity Capture-MS | BioGRID | 15778465 |
SHC1 | FLJ26504 | SHC | SHCA | SHC (Src homology 2 domain containing) transforming protein 1 | Direct interaction between IRS-1 and SHC. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human SHC | BIND | 9202037 |
- | HPRD,BioGRID | 7499194 |
SOCS1 | CIS1 | CISH1 | JAB | SOCS-1 | SSI-1 | SSI1 | TIP3 | suppressor of cytokine signaling 1 | - | HPRD,BioGRID | 11208867 |12228220
|
SOCS3 | ATOD4 | CIS3 | Cish3 | MGC71791 | SOCS-3 | SSI-3 | SSI3 | suppressor of cytokine signaling 3 | - | HPRD | 12228220 |
TUB | rd5 | tubby homolog (mouse) | - | HPRD | 10455176 |
TYK2 | JTK1 | tyrosine kinase 2 | - | HPRD,BioGRID | 8550573 |
UBTF | NOR-90 | UBF | upstream binding transcription factor, RNA polymerase I | - | HPRD,BioGRID | 12554758 |
YWHAB | GW128 | HS1 | KCIP-1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | - | HPRD,BioGRID | 9422753 |
YWHAE | 14-3-3E | FLJ45465 | KCIP-1 | MDCR | MDS | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | IRS-1 interacts with 14-3-3-epsilon isoform. This interaction was modeled on a demonstrated interaction between human IRS-1 and mouse 14-3-3-epsilon isoform. | BIND | 9111084 |
- | HPRD,BioGRID | 9111084 |9312143
|
YWHAH | YWHA1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | Affinity Capture-Western | BioGRID | 11969417 |
YWHAZ | KCIP-1 | MGC111427 | MGC126532 | MGC138156 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | - | HPRD,BioGRID | 9312143 |