Gene Page: MAL

Summary
GeneID  4118
Symbol  MAL
Synonyms  -
Description  mal, T-cell differentiation protein
See related  HGNC:6817|MIM:188860|Ensembl:ENSG00000172005|HPRD:01789|
Locus tag  -
Gene type  protein-coding
Map location  2cen-q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0004 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008289lipid bindingTAS10739088 
GO:0016505apoptotic protease activator activityNAS10366425 
GO:0015267channel activityTAS3494249 
GO:0019911structural constituent of myelin sheathIDA12153479 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007417central nervous system developmentTASBrain (GO term level: 6)10739088 
GO:0042552myelinationNASneuron, axon, Brain, oligodendrocyte (GO term level: 13)12153479 
GO:0042552myelinationTASneuron, axon, Brain, oligodendrocyte (GO term level: 13)10428054 
GO:0001766membrane raft polarizationTAS12153479 
GO:0006917induction of apoptosisNAS10366425 
GO:0030154cell differentiationTAS10739088 
GO:0045176apical protein localizationTAS10739088 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005768endosomeTAS9003426 
GO:0005783endoplasmic reticulumIDA8132541 
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS9003426 
GO:0016324apical plasma membraneTAS10739088 
GO:0045121membrane raftIDA12153479 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_MAL_PATHWAY 1917All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN 384220All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_DN 367220All SZGR genes in this pathway
JAEGER_METASTASIS_DN 258141All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
HOEBEKE_LYMPHOID_STEM_CELL_DN 8659All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN 226132All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 11785All SZGR genes in this pathway
WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN 3722All SZGR genes in this pathway
WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN 10166All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_DN 7954All SZGR genes in this pathway
MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS 3625All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 153102All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_E 8944All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
LE_EGR2_TARGETS_DN 10884All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
LU_IL4_SIGNALING 9456All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
HASLINGER_B_CLL_WITH_MUTATED_VH_GENES 1814All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_SPIKED 2213All SZGR genes in this pathway
HALMOS_CEBPA_TARGETS_DN 4626All SZGR genes in this pathway
AFFAR_YY1_TARGETS_UP 214133All SZGR genes in this pathway
RADMACHER_AML_PROGNOSIS 7852All SZGR genes in this pathway
RAMALHO_STEMNESS_DN 7455All SZGR genes in this pathway
MCDOWELL_ACUTE_LUNG_INJURY_UP 4529All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
LABBE_WNT3A_TARGETS_DN 9753All SZGR genes in this pathway
ALONSO_METASTASIS_NEURAL_UP 1813All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
CROMER_TUMORIGENESIS_DN 5129All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
LEE_DIFFERENTIATING_T_LYMPHOCYTE 200115All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE 15186All SZGR genes in this pathway
BOSCO_EPITHELIAL_DIFFERENTIATION_MODULE 6931All SZGR genes in this pathway


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