Gene Page: MYO9B

Summary
GeneID  4650
Symbol  MYO9B
Synonyms  CELIAC4|MYR5
Description  myosin IXB
See related  HGNC:7609|MIM:602129|Ensembl:ENSG00000099331|HPRD:03677|
Locus tag  -
Gene type  protein-coding
Map location  19p13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies1Link to SZGene
ExpressionExpressionP value: 1.36 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PWP10.950.95
TSR10.940.94
THUMPD30.930.93
CAPN70.930.94
C17orf710.930.94
PSPC10.930.94
PLRG10.930.93
SF3A30.920.93
SMARCA10.920.93
DIS30.920.92
Top 10 negatively co-expressed genes
MT-CO2-0.82-0.89
AF347015.31-0.82-0.88
AF347015.27-0.79-0.86
MT-CYB-0.79-0.87
AF347015.33-0.79-0.86
AF347015.8-0.78-0.88
IFI27-0.76-0.83
AF347015.21-0.75-0.86
FXYD1-0.75-0.83
AF347015.15-0.75-0.86
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000146microfilament motor activityIDA9490638 |11901422 |16616011 
GO:0000146microfilament motor activityTAS8907710 
GO:0000166nucleotide bindingIEA-
GO:0005100Rho GTPase activator activityIDA9490638 |15644318 
GO:0003779actin bindingIDA9490638 |16338935 |16616011 
GO:0003774motor activityIEA-
GO:0005096GTPase activator activityIEA-
GO:0005516calmodulin bindingIDA9490638 |16338935 
GO:0005524ATP bindingIDA16338935 
GO:0005524ATP bindingIEA-
GO:0008270zinc ion bindingIEA-
GO:0016887ATPase activityIDA16338935 
GO:0042803protein homodimerization activityIDA11901422 
GO:0019992diacylglycerol bindingIEA-
GO:0046872metal ion bindingIEA-
GO:0043531ADP bindingIDA16338935 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007242intracellular signaling cascadeIEA-
GO:0030048actin filament-based movementTAS8907710 
GO:0032011ARF protein signal transductionIDA15644318 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005737cytoplasmIDA8907710 
GO:0005938cell cortexIDA8907710 
GO:0048471perinuclear region of cytoplasmIDA8907710 
GO:0016459myosin complexIEA-
GO:0031941filamentous actinIDA8907710 |16338935 |16616011 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALM1CALML2 | CAMI | DD132 | PHKDcalmodulin 1 (phosphorylase kinase, delta)-HPRD,BioGRID9490638 
LRRC41MGC126571 | MGC126573 | MUF1 | PP7759 | RP4-636H5.2leucine rich repeat containing 41Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_RHOA_REG_PATHWAY 4630All SZGR genes in this pathway
REACTOME_SIGNALING_BY_RHO_GTPASES 11381All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_UP 276187All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN 335193All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN 180101All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN 8871All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP 13493All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 153102All SZGR genes in this pathway
AMIT_EGF_RESPONSE_480_HELA 164118All SZGR genes in this pathway
NIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER 9460All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH3_21_UP 4430All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP 8349All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP 461298All SZGR genes in this pathway
MCCABE_BOUND_BY_HOXC6 469239All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_UP 294199All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MARTENS_BOUND_BY_PML_RARA_FUSION 456287All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.13283341Ahsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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