Gene Page: PAX2

Summary
GeneID  5076
Symbol  PAX2
Synonyms  -
Description  paired box 2
See related  HGNC:8616|MIM:167409|Ensembl:ENSG00000075891|HPRD:01330|
Locus tag  -
Gene type  protein-coding
Map location  10q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
USP470.960.97
PHF30.960.97
AHCTF10.960.96
ZNF6380.950.97
RBM160.950.96
SMEK10.950.96
RSF10.950.96
TPR0.950.96
NIPBL0.950.97
ZCCHC60.950.97
Top 10 negatively co-expressed genes
AF347015.31-0.77-0.87
IFI27-0.75-0.87
MT-CO2-0.75-0.86
FXYD1-0.74-0.84
HIGD1B-0.74-0.86
AF347015.27-0.72-0.81
AF347015.33-0.71-0.80
MT-CYB-0.71-0.81
AF347015.8-0.71-0.83
ENHO-0.70-0.85
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0003677DNA bindingTAS9106533 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007409axonogenesisTASneuron, axon, neurite (GO term level: 12)9106533 
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA-
GO:0001657ureteric bud developmentIEA-
GO:0001709cell fate determinationIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0007601visual perceptionTAS9106533 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
GO:0042472inner ear morphogenesisIEA-
GO:0043010camera-type eye developmentIEA-
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA-
GO:0045449regulation of transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005815microtubule organizing centerIDA18000879 
GO:0005634nucleusIEA-
GO:0034451centriolar satelliteIDA18000879 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MAPK8JNK | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1mitogen-activated protein kinase 8-HPRD,BioGRID11700324 
MAPK8IP1IB1 | JIP-1 | JIP1 | PRKM8IPmitogen-activated protein kinase 8 interacting protein 1Affinity Capture-WesternBioGRID11700324 
PAXIP1CAGF28 | CAGF29 | FLJ41049 | PACIP1 | PAXIP1L | PTIP | TNRC2PAX interacting (with transcription-activation domain) protein 1-HPRD,BioGRID10908331 
SFRP2FRP-2 | SARP1 | SDF-5secreted frizzled-related protein 2-HPRD14561758 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN 205127All SZGR genes in this pathway
YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN 8748All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_DN 185111All SZGR genes in this pathway
SU_PANCREAS 5430All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3 9772All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_DN 5036All SZGR genes in this pathway
LI_WILMS_TUMOR 2712All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K27ME3 269159All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_DN 222147All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p11321138m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-139128812941Ahsa-miR-139brainUCUACAGUGCACGUGUCU
miR-153144214491A,m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-18515401546m8hsa-miR-185brainUGGAGAGAAAGGCAGUUC
miR-204/211199319991Ahsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
miR-21813701376m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-32911881194m8hsa-miR-329brainAACACACCUGGUUAACCUCUUU
miR-342131413201Ahsa-miR-342brainUCUCACACAGAAAUCGCACCCGUC
miR-36513951401m8hsa-miR-365UAAUGCCCCUAAAAAUCCUUAU
miR-375189819041Ahsa-miR-375UUUGUUCGUUCGGCUCGCGUGA
miR-448144314491Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-450113211381Ahsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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