Gene Page: PIP4K2A

Summary
GeneID  5305
Symbol  PIP4K2A
Synonyms  FLJ13267|PI5P4KA|PIP5K2A|PIP5KII-alpha|PIP5KIIA|PIPK
Description  phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
See related  HGNC:8997|MIM:603140|Ensembl:ENSG00000150867|HPRD:11931|
Locus tag  RP11-301N24.1
Gene type  protein-coding
Map location  10p12.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies3Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABCA80.970.86
UGT80.960.80
SLC12A20.950.82
ANLN0.950.82
ERMN0.950.76
GLDN0.940.79
CDH190.930.77
MYO1D0.930.77
PIP5K2A0.930.77
LAMP20.930.84
Top 10 negatively co-expressed genes
TBC1D10A-0.50-0.47
AC009133.1-0.47-0.51
AC006276.2-0.47-0.55
NR2C2AP-0.46-0.54
NOL12-0.46-0.52
SCNM1-0.45-0.56
BCL7C-0.45-0.59
C1orf86-0.45-0.57
DALRD3-0.45-0.50
RPL12-0.44-0.60
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
GO:00163091-phosphatidylinositol-5-phosphate 4-kinase activityIEA-
GO:00163081-phosphatidylinositol-4-phosphate 5-kinase activityNAS7639683 
GO:0016301kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016310phosphorylationNAS-
GO:0046488phosphatidylinositol metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_INOSITOL_PHOSPHATE_METABOLISM 5442All SZGR genes in this pathway
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 7656All SZGR genes in this pathway
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 216144All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM 198112All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE 3123All SZGR genes in this pathway
REACTOME_PI_METABOLISM 4834All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_UP 238144All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_6 8454All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN 483336All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
MORI_LARGE_PRE_BII_LYMPHOCYTE_DN 5839All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_DN 7652All SZGR genes in this pathway
MORI_IMMATURE_B_LYMPHOCYTE_UP 5335All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_UP 9062All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_UP 256159All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP 196137All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
BERNARD_PPAPDC1B_TARGETS_UP 4020All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_UP 518299All SZGR genes in this pathway
RAGHAVACHARI_PLATELET_SPECIFIC_GENES 7046All SZGR genes in this pathway
NOUSHMEHR_GBM_GERMLINE_MUTATED 85All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP 211131All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
LINSLEY_MIR16_TARGETS 206127All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP 11687All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-30-5p1161231A,m8hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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