Gene Page: PTK7

Summary
GeneID  5754
Symbol  PTK7
Synonyms  CCK4
Description  PTK7 protein tyrosine kinase 7
See related  HGNC:9618|MIM:601890|Ensembl:ENSG00000112655|HPRD:03534|
Locus tag  -
Gene type  protein-coding
Map location  6p21.1-p12.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RAB7A0.850.78
CTNNA20.850.83
EIF4G10.840.80
UXS10.830.78
GALNT110.810.73
HDLBP0.810.77
GNAO10.800.81
AC020663.10.790.76
PANK20.790.72
ABCF30.790.75
Top 10 negatively co-expressed genes
AF347015.21-0.68-0.55
MT-CO2-0.61-0.53
AF347015.31-0.59-0.52
C1orf54-0.59-0.51
AF347015.8-0.59-0.50
HIGD1B-0.58-0.50
AF347015.2-0.58-0.50
AF347015.33-0.57-0.49
AF347015.27-0.57-0.52
NOSTRIN-0.56-0.43
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004714transmembrane receptor protein tyrosine kinase activityTASneurite (GO term level: 8)8882711 
GO:0005021vascular endothelial growth factor receptor activityIEA-
GO:0004872receptor activityIEA-
GO:0005515protein bindingIEA-
GO:0005524ATP bindingIEA-
GO:0004713protein tyrosine kinase activityIEA-
GO:0016301kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001843neural tube closureIEA-
GO:0007155cell adhesionIEA-
GO:0006468protein amino acid phosphorylationIEA-
GO:0007165signal transductionTAS7478540 
GO:0045198establishment of epithelial cell apical/basal polarityIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIDA18029348 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0005887integral to plasma membraneTAS7478540 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_DN 536332All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_324_UP 15093All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP 176111All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_VIA_SMAD4_DN 6638All SZGR genes in this pathway
INGRAM_SHH_TARGETS_UP 12779All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_PROGNOSIS_UP 4730All SZGR genes in this pathway
LINDVALL_IMMORTALIZED_BY_TERT_DN 8056All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP 7451All SZGR genes in this pathway
WALLACE_PROSTATE_CANCER_RACE_DN 8842All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
CROMER_TUMORIGENESIS_UP 6336All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_UP 6748All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_30MIN_UP 5638All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_UP 5541All SZGR genes in this pathway
ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP 8451All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN 10677All SZGR genes in this pathway
GHANDHI_DIRECT_IRRADIATION_DN 3323All SZGR genes in this pathway


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