Gene Page: BCAT2

Summary
GeneID  587
Symbol  BCAT2
Synonyms  BCAM|BCT2
Description  branched chain aminotransferase 2, mitochondrial
See related  HGNC:977|MIM:113530|Ensembl:ENSG00000105552|HPRD:00217|
Locus tag  -
Gene type  protein-coding
Map location  19q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ANXA50.750.78
LIX10.740.74
NXT20.740.64
SLC40A10.720.62
TSPAN120.700.73
SPATA60.700.71
ENKUR0.690.71
LHFPL30.690.61
SGCE0.690.72
FIBIN0.670.64
Top 10 negatively co-expressed genes
NEUROD2-0.38-0.42
EMX1-0.38-0.48
IER5L-0.37-0.42
MPPED1-0.37-0.41
GRM2-0.36-0.41
SCUBE1-0.36-0.44
TIAM2-0.35-0.35
SLA-0.35-0.23
PRDM8-0.35-0.39
TMEM108-0.35-0.29
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004084branched-chain-amino-acid transaminase activityIEAglutamate (GO term level: 6)-
GO:0004084branched-chain-amino-acid transaminase activityTASglutamate (GO term level: 6)9165094 
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009081branched chain family amino acid metabolic processIEA-
GO:0009082branched chain family amino acid biosynthetic processTAS8702755 
GO:0008152metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0005739mitochondrionTAS9165094 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCAT2BCAM | BCT2branched chain aminotransferase 2, mitochondrial-HPRD,BioGRID11264579 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION 4426All SZGR genes in this pathway
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS 118All SZGR genes in this pathway
KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS 169All SZGR genes in this pathway
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 200136All SZGR genes in this pathway
REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM 179All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_PRENEOPLASTIC_DN 5533All SZGR genes in this pathway
CAIRO_PML_TARGETS_BOUND_BY_MYC_DN 1412All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_324_DN 14993All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN 196131All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
DAIRKEE_TERT_TARGETS_UP 380213All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_DN 203134All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_DN 4524All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
ALCALA_APOPTOSIS 8860All SZGR genes in this pathway
CHESLER_BRAIN_QTL_CIS 7551All SZGR genes in this pathway
PENG_GLUCOSE_DEPRIVATION_UP 4826All SZGR genes in this pathway
CHESLER_BRAIN_HIGHEST_GENETIC_VARIANCE 3721All SZGR genes in this pathway
NADLER_OBESITY_DN 4834All SZGR genes in this pathway
JAIN_NFKB_SIGNALING 7544All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
BURTON_ADIPOGENESIS_6 189112All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 7646All SZGR genes in this pathway
BAUS_TFF2_TARGETS_UP 3222All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK 14582All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-103/1073283341Ahsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-122148154m8hsa-miR-122aUGGAGUGUGACAAUGGUGUUUGU
miR-1462772831Ahsa-miR-146aUGAGAACUGAAUUCCAUGGGUU
hsa-miR-146bbrainUGAGAACUGAAUUCCAUAGGCU
miR-1823493551Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-25/32/92/363/36784911A,m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-93513571Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
miR-963493551Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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