Gene Page: RABGGTB

Summary
GeneID  5876
Symbol  RABGGTB
Synonyms  GGTB
Description  Rab geranylgeranyltransferase, beta subunit
See related  HGNC:9796|MIM:179080|Ensembl:ENSG00000137955|HPRD:01532|
Locus tag  RP4-682C21.3
Gene type  protein-coding
Map location  1p31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02692 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FAM177A10.830.80
TMEM680.810.80
SRP540.810.79
RAB11A0.810.83
PTGES30.810.81
RAB180.810.79
B3GALNT10.800.81
BIRC20.800.81
ASCC10.800.80
LRRC400.790.79
Top 10 negatively co-expressed genes
MT-CO2-0.57-0.65
AF347015.33-0.56-0.65
AF347015.8-0.55-0.64
AF347015.27-0.54-0.63
AF347015.31-0.54-0.63
MT-CYB-0.54-0.63
AC018755.7-0.53-0.61
FXYD1-0.53-0.61
AF347015.15-0.53-0.64
AF347015.2-0.52-0.62
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI12620389 
GO:0004659prenyltransferase activityIEA-
GO:0004663Rab-protein geranylgeranyltransferase activityIEA-
GO:0016740transferase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006464protein modification processNAS8380507 
GO:0007601visual perceptionTAS8380507 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARAFA-RAF | ARAF1 | PKS2 | RAFA1v-raf murine sarcoma 3611 viral oncogene homologTwo-hybridBioGRID12620389 
A-Raf interacts with RABGGT-beta.BIND12620389 
A-RAF interacts with RABGGT-beta.BIND12620389 
PTP4A2HH13 | HH7-2 | HU-PP-1 | OV-1 | PRL-2 | PRL2 | PTP4A | PTPCAAX2 | ptp-IV1a | ptp-IV1bprotein tyrosine phosphatase type IVA, member 2-HPRD,BioGRID11447212 
RAB3A-RAB3A, member RAS oncogene family-HPRD,BioGRID8706741 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_PRL_SIGNALING_EVENTS_PATHWAY 2317All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN 14591All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
BIDUS_METASTASIS_UP 214134All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP 633376All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
LI_LUNG_CANCER 4130All SZGR genes in this pathway
SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM 15993All SZGR genes in this pathway
SCHRAMM_INHBA_TARGETS_DN 2412All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_DN 4524All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 5135All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_DN 245154All SZGR genes in this pathway
PENG_GLUTAMINE_DEPRIVATION_DN 337230All SZGR genes in this pathway
XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_DN 1512All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
RAMALHO_STEMNESS_UP 206118All SZGR genes in this pathway
WELCSH_BRCA1_TARGETS_UP 198132All SZGR genes in this pathway
CHENG_RESPONSE_TO_NICKEL_ACETATE 4529All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN 271175All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_4NQO 3824All SZGR genes in this pathway
KYNG_DNA_DAMAGE_DN 195135All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
EHLERS_ANEUPLOIDY_UP 4129All SZGR genes in this pathway
CHEN_HOXA5_TARGETS_9HR_UP 223132All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-381981041Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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